Joon Jeong
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View article: Multicenter, Randomized, Double-Blind, Parallel, Phase 2 Clinical Trial to Compare and Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension
Multicenter, Randomized, Double-Blind, Parallel, Phase 2 Clinical Trial to Compare and Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension Open
ClinicalTrials.gov identifier: NCT06212648.
View article: Spatial analysis of tumor immune microenvironment of TNBC with different neoadjuvant chemotherapy outcomes using multiplex Immunofluorescence
Spatial analysis of tumor immune microenvironment of TNBC with different neoadjuvant chemotherapy outcomes using multiplex Immunofluorescence Open
In conclusion, our findings suggest that tumoral CD8 + and CD20 + ICs are pivotal determinants of NAC response in TNBC. The enrichment of CD20 + IC under high-TIL conditions underscores the potential role of B-T cell interactions in shapin…
View article: Retraction Note: Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer
Retraction Note: Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer Open
View article: Adipocyte-derived factors induce adherent to suspension transition in breast and pancreatic cancer cells through lipid metabolic alteration
Adipocyte-derived factors induce adherent to suspension transition in breast and pancreatic cancer cells through lipid metabolic alteration Open
Adipocytes play a dynamic role in the tumor microenvironment (TME) by acting as facilitators, providing cytokines and metabolites that regulate cancer progression and metastasis. Despite metastasis being a major contributor to cancer-assoc…
View article: Prognosis of Breast Cancer in Women in Their 20s: Clinical and Radiological Insights
Prognosis of Breast Cancer in Women in Their 20s: Clinical and Radiological Insights Open
Background/Objectives: We analyzed clinical and radiological characteristics and prognostic factors specific to young patients with breast cancer (YBC) aged <30 years. Methods: This retrospective study included 132 women aged <30 years who…
View article: Why Hoop Tension Matters: A Biomechanical Perspective on Medial Meniscus Posterior Root Tears—A Narrative Review
Why Hoop Tension Matters: A Biomechanical Perspective on Medial Meniscus Posterior Root Tears—A Narrative Review Open
This narrative review aims to provide an in-depth understanding of the biomechanical consequences of medial meniscus posterior root tears (MMPRTs), with a particular focus on the role of hoop tension in meniscal function. By revisiting fun…
View article: Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort
Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort Open
View article: P-185 Cytoplasmic Strings as a Predictive Marker for Embryo Quality and Developmental Kinetics in IVF: Association with KIDScore
P-185 Cytoplasmic Strings as a Predictive Marker for Embryo Quality and Developmental Kinetics in IVF: Association with KIDScore Open
Study question Does the presence of cytoplasmic strings (CSs) associate with Kinetics of Embryo Development Score (KIDScore) and morphokinetic parameters in embryo development? Summary answer Embryos with CSs exhibited higher KIDScore and …
View article: Additional prognostic value of the BCT score in ER+HER2- breast cancer patients receiving a 21-gene assay-guided adjuvant treatments
Additional prognostic value of the BCT score in ER+HER2- breast cancer patients receiving a 21-gene assay-guided adjuvant treatments Open
Background The 21-gene recurrence score (RS)-guided decision-making for adjuvant treatment has been utilized as a standard of care for early ER+HER2- breast cancer. We investigated a prognostic value of the Breast Cancer Test (BCT) score, …
View article: Clinical relevance of clinical treatment score post-5 years (CTS5) in HR-positive, HER2-positive breast cancer
Clinical relevance of clinical treatment score post-5 years (CTS5) in HR-positive, HER2-positive breast cancer Open
There is currently no reliable predictive tool for late recurrence in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-positive breast cancer. This study aimed to explore the potential of the clinical treatme…
View article: Pathological complete response, histologic grade, and level of stromal tumor-infiltrating lymphocytes in ER + HER2- breast cancer
Pathological complete response, histologic grade, and level of stromal tumor-infiltrating lymphocytes in ER + HER2- breast cancer Open
View article: Influence of psychological factors on the benefit from interpectoral and pectoserratus plane block for recovery after partial mastectomy: a randomized controlled trial
Influence of psychological factors on the benefit from interpectoral and pectoserratus plane block for recovery after partial mastectomy: a randomized controlled trial Open
Background: The interpectoral and pectoserratus plane (PECs) blocks have been reported to provide favorable postoperative analgesia after mastectomy. However, studies have reported controversial data regarding its effect on the quality of …
View article: Nutrient availability dictates cancer metabolism-based therapeutic responses of non-oncology drugs
Nutrient availability dictates cancer metabolism-based therapeutic responses of non-oncology drugs Open
Metabolic deregulation is a major hallmark of cancer, therefore, interventions that modify tumor nutrient availability are considered attractive adjuvants for improving clinical outcomes for cancer patients. Much work remains, however, in …
View article: Patient-reported outcomes of automated breast ultrasound: considerations for screening modality selection, based on a prospective observational survey
Patient-reported outcomes of automated breast ultrasound: considerations for screening modality selection, based on a prospective observational survey Open
Based on patient-reported outcomes, ABUS could complement handheld ultrasound in breast screening. Selecting modalities by age, BMI, breast size, and density may enhance satisfaction and resource use. Personalized strategies may improve sc…
View article: Decision-Making Patterns for Clinically Node-Positive, Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: Insights From a Survey of Breast Cancer Experts
Decision-Making Patterns for Clinically Node-Positive, Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: Insights From a Survey of Breast Cancer Experts Open
The findings reveal both consensus and variability in clinical decision-making for HR+HER2- breast cancer with suspected LN involvement among multinational breast cancer specialists. This underscores the need for enhanced international col…
View article: Long-term oncologic outcome of intraoperative radiotherapy (IORT) with low-energy X-rays as a tumor-bed boost in Korean patients with breast cancer
Long-term oncologic outcome of intraoperative radiotherapy (IORT) with low-energy X-rays as a tumor-bed boost in Korean patients with breast cancer Open
We identified the oncologic safety of IORT with low-energy X-rays as a tumor-bed boost in Korean patients during an extended follow-up period.
View article: In Vivo Conductivity of Normal Fibroglandular Tissue Using MR Electrical Properties Tomography: A Comparison With Apparent Diffusion Coefficient
In Vivo Conductivity of Normal Fibroglandular Tissue Using MR Electrical Properties Tomography: A Comparison With Apparent Diffusion Coefficient Open
View article: Body Mass Index and Progesterone Receptor in Postmenopausal Er-Positive/Her2-Negative Breast Cancer: A Nation-Wide Study in Korean Breast Cancer Society and the Multi-Institutional Cohort
Body Mass Index and Progesterone Receptor in Postmenopausal Er-Positive/Her2-Negative Breast Cancer: A Nation-Wide Study in Korean Breast Cancer Society and the Multi-Institutional Cohort Open
View article: Stromal tumor-infiltrating lymphocytes and pathologic response to neoadjuvant chemotherapy with the addition of platinum and pembrolizumab in TNBC: a single-center real-world study
Stromal tumor-infiltrating lymphocytes and pathologic response to neoadjuvant chemotherapy with the addition of platinum and pembrolizumab in TNBC: a single-center real-world study Open
Background Immunochemotherapy with pembrolizumab has been integrated into clinical practice as part of the standard-of-care for non-metastatic triple-negative breast cancer (TNBC) with high risk. We conducted a real-world study in TNBC pat…
View article: Cell competition reprograms adherent-suspension plasticity in disseminated tumor cells
Cell competition reprograms adherent-suspension plasticity in disseminated tumor cells Open
Cell competition within the primary tumor drives tumor growth by promoting the uncontrolled proliferation of winner cells and eliminating loser cells by sensing cell fitness. However, the mechanism of how cell competition confers the loser…
View article: Correction: Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 HR + HER2- breast cancer: a retrospective analysis
Correction: Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 HR + HER2- breast cancer: a retrospective analysis Open
View article: Immune environment of high-TIL breast cancer: triple negative and hormone receptor positive HER2 negative
Immune environment of high-TIL breast cancer: triple negative and hormone receptor positive HER2 negative Open
View article: Clinical Relevance of TP53 Mutation and Its Characteristics in Breast Cancer with Long-Term Follow-Up Date
Clinical Relevance of TP53 Mutation and Its Characteristics in Breast Cancer with Long-Term Follow-Up Date Open
Background: The TP53 mutation is one of the most frequently identified mutations in human cancers and is typically associated with a poor prognosis. However, there are conflicting findings regarding its impact. We aimed to clarify the clin…
View article: Nipple-areolar complex sensory recovery based on incision placement after nipple-sparing mastectomy: a prospective nonrandomized controlled trial
Nipple-areolar complex sensory recovery based on incision placement after nipple-sparing mastectomy: a prospective nonrandomized controlled trial Open
Introduction: Nipple-sparing mastectomy (NSM) aims to improve patient satisfaction by preserving the nipple-areola complex (NAC) while ensuring oncologic safety. Different surgical incisions, such as inframammary fold (IMF) and periareolar…
View article: Age and Late Recurrence in Young Patients With ER–Positive, <i>ERBB2</i>-Negative Breast Cancer
Age and Late Recurrence in Young Patients With ER–Positive, <i>ERBB2</i>-Negative Breast Cancer Open
Importance Young patients with breast cancer with estrogen receptor (ER)–positive, ERBB2 -negative tumors have a poor prognosis. Understanding factors influencing late recurrence is crucial for improving management and outcomes. Objective …
View article: Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 HR + HER2- breast cancer: a retrospective analysis
Differentiating HER2-low and HER2-zero tumors with 21-gene multigene assay in 2,295 HR + HER2- breast cancer: a retrospective analysis Open
View article: Prediction of menstrual recovery patterns in premenopausal women with breast cancer taking tamoxifen after chemotherapy: an ASTRRA Substudy
Prediction of menstrual recovery patterns in premenopausal women with breast cancer taking tamoxifen after chemotherapy: an ASTRRA Substudy Open
View article: Locoregional recurrence after neoadjuvant versus adjuvant chemotherapy based on tumor subtypes in patients with early-stage breast cancer: A multi-institutional retrospective cohort study
Locoregional recurrence after neoadjuvant versus adjuvant chemotherapy based on tumor subtypes in patients with early-stage breast cancer: A multi-institutional retrospective cohort study Open
View article: Prediction Model for Individualized Precision Surgery in Breast Cancer Patients with Complete Response on MRI and Residual Calcifications on Mammography after Neoadjuvant Chemotherapy
Prediction Model for Individualized Precision Surgery in Breast Cancer Patients with Complete Response on MRI and Residual Calcifications on Mammography after Neoadjuvant Chemotherapy Open
Background To investigate factors predicting calcifications without residual carcinoma (ypCalc_0) or with residual carcinoma (ypCalc_ca) and to develop a prediction model for patients exhibiting residual suspicious calcifications on mammog…
View article: Measuring patient‐reported distress from breast magnetic resonance imaging: Development and validation of the <scp>MRI</scp>‐related distress scale (<scp>MRI</scp>‐<scp>DS</scp>)
Measuring patient‐reported distress from breast magnetic resonance imaging: Development and validation of the <span>MRI</span>‐related distress scale (<span>MRI</span>‐<span>DS</span>) Open
Objective Although breast magnetic resonance imaging (MRI) is a valuable screening tool, breast MRI testing burden was associated with cancer worry and quality of life. We aimed to develop and validate the MRI‐related distress scale (MRI‐D…