JoonNyung Heo
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View article: Automated ischemic stroke lesion detection on non-contrast brain CT: a large-scale clinical feasibility test AI stroke lesion detection on NCCT
Automated ischemic stroke lesion detection on non-contrast brain CT: a large-scale clinical feasibility test AI stroke lesion detection on NCCT Open
Background Non-contrast CT (NCCT) is widely used imaging modality for acute stroke imaging but often fails to detect subtle early ischemic changes. Such underestimation can lead clinicians to overlook tissue-level information. This study a…
View article: Thrombus composition and distribution patterns by thrombus volume in acute ischemic stroke
Thrombus composition and distribution patterns by thrombus volume in acute ischemic stroke Open
Background Thrombus burden considerably impacts ischemic stroke presentation and outcomes. However, the relationship between thrombus histology and volume has not been studied well. We investigated whether ischemic stroke thrombus composit…
View article: Automated Ischemic Stroke Lesion Detection On Non-Contrast Brain CT: A Large-Scale Clinical Feasibility Test
Automated Ischemic Stroke Lesion Detection On Non-Contrast Brain CT: A Large-Scale Clinical Feasibility Test Open
Background Non-contrast CT (NCCT) is widely used imaging modality for acute stroke imaging but often fails to detect subtle early ischemic changes. Such underestimation can lead clinicians to overlook tissue-level information. This study a…
View article: Blood pressure management based on infarct volume after successful endovascular thrombectomy
Blood pressure management based on infarct volume after successful endovascular thrombectomy Open
Introduction: While the efficacy of endovascular thrombectomy (EVT) in large core infarcts has been established, the influence of blood pressure (BP) management on functional outcomes based on infarct volume remains unclear. Patients and m…
View article: Association Between Estimated Pulse Wave Velocity and Endovascular Thrombectomy Outcome: A Secondary Analysis of the OPTIMAL‐BP Trial
Association Between Estimated Pulse Wave Velocity and Endovascular Thrombectomy Outcome: A Secondary Analysis of the OPTIMAL‐BP Trial Open
Background The link between arterial stiffness, measured by estimated pulse wave velocity (ePWV), and outcomes following endovascular thrombectomy (EVT) has not been tested. This study aimed to determine whether ePWV predicts post‐EVT outc…
View article: Application of Artificial Intelligence in Acute Ischemic Stroke: A Scoping Review
Application of Artificial Intelligence in Acute Ischemic Stroke: A Scoping Review Open
Artificial intelligence (AI) is revolutionizing stroke care by enhancing diagnosis, treatment, and outcome prediction. This review examines 505 original studies on AI applications in ischemic stroke, categorized into outcome prediction, st…
View article: Korea Hypertension Fact Sheet 2024: nationwide population-based analysis with a focus on young adults
Korea Hypertension Fact Sheet 2024: nationwide population-based analysis with a focus on young adults Open
While South Korea has achieved relatively high rates of hypertension management compared to many countries, further efforts are needed to reduce hypertension prevalence and improve awareness and treatment adherence, particularly among youn…
View article: Microembolic Signals on Transcranial Doppler Ultrasonography: A Narrative Review of a Decade of Evidence
Microembolic Signals on Transcranial Doppler Ultrasonography: A Narrative Review of a Decade of Evidence Open
Microembolic signals (MESs), detected via transcranial Doppler ultrasonography, are essential biomarkers for assessing cerebrovascular risk, embolic events, and treatment outcomes. In this review, studies published between 2014 and 2024 we…
View article: Long-Term Outcome of Rescue Stenting for Acute Intracranial Atherosclerotic Stenosis–Related Large Vessel Occlusion in the Anterior Circulation
Long-Term Outcome of Rescue Stenting for Acute Intracranial Atherosclerotic Stenosis–Related Large Vessel Occlusion in the Anterior Circulation Open
Patients with RS for ICAS-LVO showed a low stroke recurrence rate in the long-term. The long-term patency of RS appears to remain durable, particularly when it remained patent during the initial follow-up.
View article: Arterial Stiffness Predicts the Outcome of Endovascular Treatment in Patients with Acute Ischemic Stroke
Arterial Stiffness Predicts the Outcome of Endovascular Treatment in Patients with Acute Ischemic Stroke Open
Background: The association between arterial stiffness and outcome after endovascular treatment (EVT) is unknown. This study investigated whether arterial stiffness predicts post-EVT outcome in patients with acute ischemic stroke. Methods:…
View article: Early vascular aging determined by brachial-ankle pulse wave velocity and its impact on ischemic stroke outcome: a retrospective observational study
Early vascular aging determined by brachial-ankle pulse wave velocity and its impact on ischemic stroke outcome: a retrospective observational study Open
Vascular aging phenotype may be useful in predicting stroke prognosis. In the present study, the relationship between vascular aging phenotypes and outcomes after acute ischemic stroke was investigated. The study included consecutive patie…
View article: Long-term outcomes of patients with embolic stroke of undetermined source according to subtype
Long-term outcomes of patients with embolic stroke of undetermined source according to subtype Open
View article: Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy
Functional Outcomes Associated With Blood Pressure Decrease After Endovascular Thrombectomy Open
Importance The associations between blood pressure (BP) decreases induced by medication and functional outcomes in patients with successful endovascular thrombectomy remain uncertain. Objective To evaluate whether BP reductions induced by …
View article: Combined use of anticoagulant and antiplatelet on outcome after stroke in patients with nonvalvular atrial fibrillation and systemic atherosclerosis
Combined use of anticoagulant and antiplatelet on outcome after stroke in patients with nonvalvular atrial fibrillation and systemic atherosclerosis Open
This study aimed to investigate whether there was a difference in one-year outcome after stroke between patients treated with antiplatelet and anticoagulation (OAC + antiplatelet) and those with anticoagulation only (OAC), when comorbid at…
View article: Long-term outcomes of patients with embolic stroke of undetermined source according to subtype
Long-term outcomes of patients with embolic stroke of undetermined source according to subtype Open
Background and Aims: The prognosis of patients with embolic stroke of undetermined source (ESUS) may vary according to the underlying cause. Therefore, we aimed to divide ESUS into subtypes and assess the long-term outcomes. Methods: Conse…
View article: Intensive vs Conventional Blood Pressure Lowering After Endovascular Thrombectomy in Acute Ischemic Stroke
Intensive vs Conventional Blood Pressure Lowering After Endovascular Thrombectomy in Acute Ischemic Stroke Open
Importance Optimal blood pressure (BP) control after successful reperfusion with endovascular thrombectomy (EVT) for patients with acute ischemic stroke is unclear. Objective To determine whether intensive BP management during the first 24…
View article: Cancer Prediction With Machine Learning of Thrombi From Thrombectomy in Stroke: Multicenter Development and Validation
Cancer Prediction With Machine Learning of Thrombi From Thrombectomy in Stroke: Multicenter Development and Validation Open
BACKGROUND: We aimed to develop and validate machine learning models to diagnose patients with ischemic stroke with cancer through the analysis of histopathologic images of thrombi obtained during endovascular thrombectomy. METHODS: This w…
View article: Prognostic value of central blood pressure on the outcomes of embolic stroke of undetermined source
Prognostic value of central blood pressure on the outcomes of embolic stroke of undetermined source Open
View article: Acute Brain Infarction in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
Acute Brain Infarction in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Open
Objectives This study investigated the clinical and radiological features of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with acute brain infarction, using a cohort of Korean patients with AAV. Methods T…
View article: Development of Software Solutions for Stroke: A Personal Experience
Development of Software Solutions for Stroke: A Personal Experience Open
Variety of software solutions are being used for clinical use. This special contribution focuses on the personal experience of developing several software solutions concerning stroke. Stroke119 application was developed to inform the patie…
View article: Impact of Left Atrial or Left Atrial Appendage Thrombus on Stroke Outcome: A Matched Control Analysis
Impact of Left Atrial or Left Atrial Appendage Thrombus on Stroke Outcome: A Matched Control Analysis Open
Background and Purpose Left atrial or left atrial appendage (LA/LAA) thrombi are frequently observed during cardioembolic evaluation in patients with ischemic stroke. This study aimed to investigate stroke outcomes in patients with LA/LAA …
View article: Automated Composition Analysis of Thrombus from Endovascular Treatment in Acute Ischemic Stroke Using Computer Vision
Automated Composition Analysis of Thrombus from Endovascular Treatment in Acute Ischemic Stroke Using Computer Vision Open
View article: Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy
Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy Open
Background: CHADS2, CHA2DS2-VASc, ATRIA, and Essen stroke risk scores are used to estimate thromboembolism risk. We aimed to investigate the association between unfavorable outcomes and stroke risk scores in patients who received endovascu…
View article: Association between blood viscosity and early neurological deterioration in lacunar infarction
Association between blood viscosity and early neurological deterioration in lacunar infarction Open
Background Understanding the factors related to early neurologic deterioration (END) is crucial in the management of patients with lacunar infarction. Blood viscosity is a significant factor for microvascular perfusion. We investigated the…
View article: Early depression screening and short-term functional outcome in hospitalized patients for acute ischemic stroke
Early depression screening and short-term functional outcome in hospitalized patients for acute ischemic stroke Open
Background Patients with ischemic stroke are at high risk for post-stroke depression (PSD). There are limited data regarding the clinical impact of early PSD, assessed in hospitalized patients with acute ischemic stroke. Methods This hospi…
View article: Association between Low Ankle-Brachial Index and Poor Outcomes in Patients with Embolic Stroke of Undetermined Source
Association between Low Ankle-Brachial Index and Poor Outcomes in Patients with Embolic Stroke of Undetermined Source Open
We investigated the association of low ankle-brachial index (ABI < 0.9) with major adverse cardiovascular events (MACE) and all-cause mortality in patients with embolic stroke of undetermined source (ESUS) as well as whether the associatio…
View article: Impact of Sarcopenia on Functional Outcomes Among Patients With Mild Acute Ischemic Stroke and Transient Ischemic Attack: A Retrospective Study
Impact of Sarcopenia on Functional Outcomes Among Patients With Mild Acute Ischemic Stroke and Transient Ischemic Attack: A Retrospective Study Open
Introduction Sarcopenia, a age-related disease characterized by loss of muscle mass accompanied by loss of function, is associated with nutrition imbalance, physical inactivity, insulin resistance, inflammation, metabolic syndrome, and ath…
View article: Risks and Benefits of Early Rhythm Control in Patients With Acute Strokes and Atrial Fibrillation: A Multicenter, Prospective, Randomized Study (the RAFAS Trial)
Risks and Benefits of Early Rhythm Control in Patients With Acute Strokes and Atrial Fibrillation: A Multicenter, Prospective, Randomized Study (the RAFAS Trial) Open
Background The purpose of the RAFAS (Risk and Benefits of Urgent Rhythm Control of Atrial Fibrillation in Patients With Acute Stroke) trial was to explore the risks and benefits of early rhythm control in patients with newly documented atr…
View article: Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients
Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients Open
Background: The CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after e…
View article: Validation of Machine Learning Models to Predict Adverse Outcomes in Patients with COVID-19: A Prospective Pilot Study
Validation of Machine Learning Models to Predict Adverse Outcomes in Patients with COVID-19: A Prospective Pilot Study Open
Our machine learning models showed good performance for predicting the outcomes of COVID-19 patients and could thus be useful for patient triage and monitoring.