Jordan E. Pierce
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View article: The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium
The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium Open
Cognitive reappraisal is a fundamental emotion regulation strategy for mental and physical well-being, but how its neural mechanisms relate to individual differences remains poorly understood. In a consortium effort analyzing 40 fMRI datas…
View article: Segregation of Three Resting-State Brain Networks Predicts Reappraisal Success Across The Lifespan
Segregation of Three Resting-State Brain Networks Predicts Reappraisal Success Across The Lifespan Open
Cognitive reappraisal is a form of emotion regulation that involves the reinterpretation of stimuli to change one’s emotional state, often to reduce negative affect. Emotion regulation fMRI tasks generally yield increased activation in pre…
View article: Chronic Stress May Amplify Gender/Sex Differences in Amygdala Reactivity to Ambiguous Emotional Stimuli
Chronic Stress May Amplify Gender/Sex Differences in Amygdala Reactivity to Ambiguous Emotional Stimuli Open
Heightened reactivity to ambiguous emotional stimuli, such as surprized faces, is a transdiagnostic psychopathology risk factor. Women show elevated amygdala activation to ambiguous emotional stimuli relative to men, which may underlie the…
View article: Intersection of biases: In-group positivity for racially diverse ambiguous facial expressions
Intersection of biases: In-group positivity for racially diverse ambiguous facial expressions Open
Emotional expressions offer important social cues about the expresser’s intentions and risks or rewards in the environment. The current study investigated how individual differences in interpretation of ambiguous facial expressions (valenc…
View article: Differential Engagement of Associative-Limbic and Sensorimotor Regions of the Cerebellum and Basal Ganglia in Explicit vs. Implicit Emotional Processing
Differential Engagement of Associative-Limbic and Sensorimotor Regions of the Cerebellum and Basal Ganglia in Explicit vs. Implicit Emotional Processing Open
Emotional prosody processing involves multiple brain regions, but the specific roles of the cerebellum and basal ganglia in explicit (conscious) and implicit (incidental) tasks are not well known or understood. This study investigated how …
View article: Resting-state functional network segregation of the default mode network predicts valence bias across the lifespan
Resting-state functional network segregation of the default mode network predicts valence bias across the lifespan Open
The brain is organized into intrinsically connected functional networks that can be reliably identified during resting-state functional magnetic resonance imaging (fMRI). Healthy aging is marked by decreased network segregation, which is l…
View article: Specialized late cingulo-opercular network activation elucidates the mechanisms underlying decisions about ambiguity
Specialized late cingulo-opercular network activation elucidates the mechanisms underlying decisions about ambiguity Open
Cortical task control networks, including the cingulo-opercular (CO) network play a key role in decision-making across a variety of functional domains. In particular, the CO network functions in a performance reporting capacity that suppor…
View article: Specialized late cingulo-opercular network activation elucidates the mechanisms underlying decisions about ambiguity
Specialized late cingulo-opercular network activation elucidates the mechanisms underlying decisions about ambiguity Open
Cortical task control networks, including the cingulo-opercular (CO) network play a key role in decision-making across a variety of functional domains. In particular, the CO network functions in a performance reporting capacity that suppor…
View article: Affective flexibility as a developmental building block of cognitive reappraisal: An fMRI study
Affective flexibility as a developmental building block of cognitive reappraisal: An fMRI study Open
Cognitive reappraisal is a form of emotion regulation that involves reinterpreting the meaning of a stimulus, often to downregulate one's negative affect. Reappraisal typically recruits distributed regions of prefrontal and parietal cortex…
View article: Explicit and Implicit Emotion Processing in the Cerebellum: A Meta-analysis and Systematic Review
Explicit and Implicit Emotion Processing in the Cerebellum: A Meta-analysis and Systematic Review Open
The cerebellum’s role in affective processing is increasingly recognized in the literature, but remains poorly understood, despite abundant clinical evidence for affective disruptions following cerebellar damage. To improve the characteriz…
View article: Age-related differences in the extent to which affective flexibility predicts reappraisal ability
Age-related differences in the extent to which affective flexibility predicts reappraisal ability Open
Affective flexibility is a crucial emotional skill that can be conceptualized as an ability to appraise complex emotional stimuli in more than one way. Here, we investigated affective flexibility as variability in interpretations of ambigu…
View article: Long COVID Neuropsychological Deficits after Severe, Moderate, or Mild Infection
Long COVID Neuropsychological Deficits after Severe, Moderate, or Mild Infection Open
There is growing awareness that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, even in its mild or moderate respiratory forms, can include long-term neuropsychological deficits. Standardized neuropsychological, psy…
View article: Reappraisal-related downregulation of amygdala BOLD activation occurs only during the late trial window
Reappraisal-related downregulation of amygdala BOLD activation occurs only during the late trial window Open
During cognitive reappraisal, an individual reinterprets the meaning of an emotional stimulus to regulate the intensity of their emotional response. Prefrontal cortex activity has been found to support reappraisal and is putatively thought…
View article: Motor Symptom Asymmetry Predicts Non-motor Outcome and Quality of Life Following STN DBS in Parkinson's Disease
Motor Symptom Asymmetry Predicts Non-motor Outcome and Quality of Life Following STN DBS in Parkinson's Disease Open
Risk factors for long-term non-motor disorders and quality of life following subthalamic nucleus deep-brain stimulation (STN DBS) have not yet been fully identified. In the present study, we investigated the impact of motor symptom asymmet…
View article: Long COVID Neuropsychological Deficits After Severe, Moderate or Mild Infection
Long COVID Neuropsychological Deficits After Severe, Moderate or Mild Infection Open
Background: There is growing awareness that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can include long-term neuropsychological deficits, even in its mild or moderate respiratory forms.Methods: Standardized neur…
View article: A novel computerized assessment of manual spatial exploration in unilateral spatial neglect
A novel computerized assessment of manual spatial exploration in unilateral spatial neglect Open
Unilateral spatial neglect is a neuropsychological syndrome commonly observed after stroke and defined by the inability to attend or respond to contralesional stimuli. Typically, symptoms are assessed using clinical tests that rely upon vi…
View article: The basal ganglia and the cerebellum in human emotion
The basal ganglia and the cerebellum in human emotion Open
The basal ganglia (BG) and the cerebellum historically have been relegated to a functional role in producing or modulating motor output. Recent research, however, has emphasized the importance of these subcortical structures in multiple fu…
View article: Regularized aggregation of statistical parametric maps
Regularized aggregation of statistical parametric maps Open
Combining statistical parametric maps (SPM) from individual subjects is the goal in some types of group‐level analyses of functional magnetic resonance imaging data. Brain maps are usually combined using a simple average across subjects, m…
View article: Evaluating the Specificity of Cognitive Control Deficits in Schizophrenia Using Antisaccades, Functional Magnetic Resonance Imaging, and Healthy Individuals With Poor Cognitive Control
Evaluating the Specificity of Cognitive Control Deficits in Schizophrenia Using Antisaccades, Functional Magnetic Resonance Imaging, and Healthy Individuals With Poor Cognitive Control Open
Cognitive control impairments in schizophrenia (SZ) can be evaluated using antisaccade tasks and functional magnetic resonance imaging (fMRI). Studies, however, often compare people with SZ to high performing healthy people, making it uncl…
View article: Structural brain abnormalities in 12 persons with aniridia
Structural brain abnormalities in 12 persons with aniridia Open
Background:Aniridia is a disorder predominately caused by heterozygous loss-of-function mutations of thePAX6gene, which is a transcriptional regulator necessary for normal eye and brain development. The ocular abnormalities of aniridia hav…
View article: Structural brain abnormalities in 12 persons with aniridia
Structural brain abnormalities in 12 persons with aniridia Open
Background:Aniridia is a disorder predominately caused by heterozygous loss-of-function mutations of thePAX6gene, which is a transcriptional regulator necessary for normal eye and brain development. The ocular abnormalities of aniridia hav…