Jörg Rau
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View article: Up-to-date MALDI-TOF MS based identification of the complete <i>Corynebacterium diphtheriae</i> species complex for improved diagnostics
Up-to-date MALDI-TOF MS based identification of the complete <i>Corynebacterium diphtheriae</i> species complex for improved diagnostics Open
The Corynebacterium ( C. ) diphtheriae species complex ( Cd SC) comprises the closely related pathogenic species C. diphtheriae , C. belfantii, C. rouxii, C. ulcerans, C. silvaticum, C. ramonii and C. pseudotuberculosis according to the ta…
View article: Establishment and Thorough External Validation of a FTIR Spectroscopy Classifier for <i>Salmonella</i> Serogroup Differentiation
Establishment and Thorough External Validation of a FTIR Spectroscopy Classifier for <i>Salmonella</i> Serogroup Differentiation Open
As one of the most relevant food-borne pathogens, the reliable detection, confirmation and fine-typing of Salmonella strains is very important. Salmonella serotype determination by rabbit antisera posts the worldwide-accepted standard but …
View article: Occurrence and Monitoring of the Zoonotic Pathogen Yersinia pseudotuberculosis in Various Zoo Animal Species
Occurrence and Monitoring of the Zoonotic Pathogen Yersinia pseudotuberculosis in Various Zoo Animal Species Open
Infections with the zoonotic pathogen Yersinia (Y.) pseudotuberculosis are commonly causing clinical diseases and acute deaths in various mammal and bird species in zoos. These findings prompted us to conduct a targeted study that included…
View article: A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria
A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria Open
Today, MALDI-ToF MS is an established technique to characterize and identify pathogenic bacteria. The technique is increasingly applied by clinical microbiological laboratories that use commercially available complete solutions, including …
View article: Reliable delineation of Bacillus cytotoxicus from other members of the Bacillus cereus group by MALDI-TOF MS – An extensive validation study
Reliable delineation of Bacillus cytotoxicus from other members of the Bacillus cereus group by MALDI-TOF MS – An extensive validation study Open
View article: Complete genome sequence of <i>Arcanobacterium wilhelmae</i> strain DSM 102162 isolated from the genital tract of a <i>Rhinoceros unicornis</i>
Complete genome sequence of <i>Arcanobacterium wilhelmae</i> strain DSM 102162 isolated from the genital tract of a <i>Rhinoceros unicornis</i> Open
Previous case reports indicate Arcanobacterium ’s opportunistic pathogenic potential. However, the true diversity of the genus remains understudied. Here, we present the complete genome of Arcanobacterium wilhelmae isolated from a diseased…
View article: <i>Klebsiella pneumoniae</i> arms itself: poultry food chain drives spread and evolution of <i>mcr-1.26-</i> IncX4 plasmids
<i>Klebsiella pneumoniae</i> arms itself: poultry food chain drives spread and evolution of <i>mcr-1.26-</i> IncX4 plasmids Open
View article: Validated differentiation of Listeria monocytogenes serogroups by FTIR spectroscopy using an Artificial Neural Network based classifier in an accredited official food control laboratory
Validated differentiation of Listeria monocytogenes serogroups by FTIR spectroscopy using an Artificial Neural Network based classifier in an accredited official food control laboratory Open
Listeria monocytogenes is a well-known human pathogen, and especially the young, the elderly, otherwise immunocompromised individuals or pregnant women might suffer severe health consequences from listeriosis. Up to date, Fourier-Transform…
View article: Corynebacterium ulcerans Infections in Eurasian Beavers (Castor fiber)
Corynebacterium ulcerans Infections in Eurasian Beavers (Castor fiber) Open
The Eurasian beaver (Castor fiber) has been reintroduced successfully in Germany since the 1990s. Since wildlife is an important source of zoonotic infectious diseases, monitoring of invasive and reintroduced species is crucial with respec…
View article: Checkliste „Food Defense“ – ein Hilfsmittel für die Schwachstellenanalyse in Lebensmittelbetrieben
Checkliste „Food Defense“ – ein Hilfsmittel für die Schwachstellenanalyse in Lebensmittelbetrieben Open
Zusammenfassung Konzepte über Food Defense (Lebensmittel-Produktschutz) sollen Lebensmittel vor mutwilligen Kontaminationen schützen. Aufgrund von Zertifizierungsanforderungen oder Exportregularien besteht auch ohne nationale oder europäis…
View article: Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys chartarum
Production of Satratoxin G and H Is Tightly Linked to Sporulation in Stachybotrys chartarum Open
Stachybotrys chartarum is a toxigenic fungus that is frequently isolated from damp building materials or improperly stored forage. Macrocyclic trichothecenes and in particular satratoxins are the most potent mycotoxins known to be produced…
View article: Corynebacterium pseudotuberculosis Infections in Alpacas (Vicugna pacos)
Corynebacterium pseudotuberculosis Infections in Alpacas (Vicugna pacos) Open
Alpacas are the major camelid species in Europe held for hobbies, animal-aided therapy, and commercial reasons. As a result, health-related issues associated with alpacas are of growing significance. This especially holds true for one of t…
View article: Fatal Infection in an Alpaca (Vicugna pacos) Caused by Pathogenic Rhodococcus equi
Fatal Infection in an Alpaca (Vicugna pacos) Caused by Pathogenic Rhodococcus equi Open
Rhodococcus (R.) equi is a pathogen primarily known for infections in equine foals, but is also present in numerous livestock species including New World camelids. Moreover, R. equi is considered an emerging zoonotic pathogen. In this repo…
View article: Aus der § 64 LFGB-Arbeitsgruppe MALDI-TOF: Leitlinien für die Validierung von Spezies-Identifizierungen mittels MALDI-TOF-MS
Aus der § 64 LFGB-Arbeitsgruppe MALDI-TOF: Leitlinien für die Validierung von Spezies-Identifizierungen mittels MALDI-TOF-MS Open
Matrix-assisted laser-desorption/ionization-time-of-flight-mass-spectrometry (MALDI-TOF-MS) is widely used to identify microorganisms. Recently, new applications such as identification of the animal species from meat, milk or fish are emer…
View article: First isolation of Arcanobacterium pinnipediorum from a grey seal pup (Halichoerus grypus) in the UK
First isolation of Arcanobacterium pinnipediorum from a grey seal pup (Halichoerus grypus) in the UK Open
View article: Widespread Disease in Hedgehogs (<i>Erinaceus europaeus</i>) Caused by Toxigenic <i>Corynebacterium ulcerans</i>
Widespread Disease in Hedgehogs (<i>Erinaceus europaeus</i>) Caused by Toxigenic <i>Corynebacterium ulcerans</i> Open
Toxin-producing Corynebacterium ulcerans, a causative agent of diphtheria in humans, was isolated from 53 hedgehogs in Belgium during the spring of 2020. Isolates showed low levels of acquired antimicrobial drug resistance. Strain diversit…
View article: Corynebacterium rouxii, a recently described member of the C. diphtheriae group isolated from three dogs with ulcerative skin lesions
Corynebacterium rouxii, a recently described member of the C. diphtheriae group isolated from three dogs with ulcerative skin lesions Open
Corynebacterium ( C. ) diphtheriae is one of the two etiological pathogens for human diphtheria with significant morbidity and mortality. Recently, members of its biovar Belfanti have been described as two novel species, C. belfantii and C…
View article: Genome-Based Analysis of Klebsiella spp. Isolates from Animals and Food Products in Germany, 2013–2017
Genome-Based Analysis of Klebsiella spp. Isolates from Animals and Food Products in Germany, 2013–2017 Open
The increase in infections with multidrug-resistant and virulent Klebsiella pneumoniae (K. pneumoniae) strains poses a serious threat to public health. However, environmental reservoirs and routes of transmission for Klebsiella spp. that c…
View article: Animal Species Identification of Meat Using MALDI-TOF Mass Spectrometry
Animal Species Identification of Meat Using MALDI-TOF Mass Spectrometry Open
We describe the animal species identification of meat using MALDI-TOF mass spectroscopy including the development and validation of a reliable method, qualified for use in the accredited official food-control laboratory. Previous publicati…
View article: Animal Species Identification of Meat Using MALDI-TOF Mass Spectrometry
Animal Species Identification of Meat Using MALDI-TOF Mass Spectrometry Open
We describe the animal species identification of meat using MALDI-TOF mass spectroscopy including the development and validation of a reliable method, qualified for use in the accredited official food-control laboratory. Previous publicati…
View article: Kurkuma – mit Schwermetallen verunreinigt?
Kurkuma – mit Schwermetallen verunreinigt? Open
Summary Spices are among the most frequently adulterated foods. According to a recent study, turmeric from Bangladesh, one of the main producing countries, was found to be contaminated with lead at levels of up to 1 g/kg, …
View article: Streptobacillus felis, a member of the oropharynx microbiota of the Felidae, isolated from a tropical rusty-spotted cat
Streptobacillus felis, a member of the oropharynx microbiota of the Felidae, isolated from a tropical rusty-spotted cat Open
View article: Toxigenic and zoonotic<i>Corynebacterium ulcerans</i>emerges from widespread hedgehog disease
Toxigenic and zoonotic<i>Corynebacterium ulcerans</i>emerges from widespread hedgehog disease Open
Toxin-producing Corynebacterium ulcerans , causing diphtheria in humans, were isolated from 53 diseased hedgehogs during spring 2020 in Belgium. Isolates showed low levels of acquired antimicrobial resistance. Pronounced strain diversity s…
View article: Actinomycetes associated with abscess formation in a goat, a llama and two alpacas
Actinomycetes associated with abscess formation in a goat, a llama and two alpacas Open
The genera Actinomyces and Schaalia, both members of the bacterial order Actinomycetales, include relevant infectious agents that cause abscesses in small ruminants and New World camelids. Due to the high diversity of the Actinomycetales, …
View article: Artificial neural network-assisted Fourier transform infrared spectroscopy for differentiation of<i>Salmonella</i>serogroups and its application on epidemiological tracing of<i>Salmonella</i>Bovismorbificans outbreak isolates from fresh sprouts
Artificial neural network-assisted Fourier transform infrared spectroscopy for differentiation of<i>Salmonella</i>serogroups and its application on epidemiological tracing of<i>Salmonella</i>Bovismorbificans outbreak isolates from fresh sprouts Open
Salmonellae represent one of the most common bacterial infection reagents in both humans and animals. For detection and epidemiological elucidation of Salmonella infections, determination of Salmonella serotypes and differentiation between…
View article: <i>Tox</i> -positive <i>Corynebacterium ulcerans</i> in hedgehogs, Germany
<i>Tox</i> -positive <i>Corynebacterium ulcerans</i> in hedgehogs, Germany Open
Toxigenic Corynebacterium ulcerans may cause both respiratory and cutaneous diphtheria in humans. As a zoonotic emerging pathogen it has been isolated from a wide variety of animals living in captivity, such as livestock, pet, zoo and rese…
View article: Typing and Species Identification of Clinical Klebsiella Isolates by Fourier Transform Infrared Spectroscopy and Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
Typing and Species Identification of Clinical Klebsiella Isolates by Fourier Transform Infrared Spectroscopy and Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Open
Klebsiella pneumoniae and related species are frequent causes of nosocomial infections and outbreaks. Therefore, quick and reliable strain typing is crucial for the detection of transmission routes in the hospital.
View article: A multiplex real-time PCR for the detection and differentiation of Campylobacter phages
A multiplex real-time PCR for the detection and differentiation of Campylobacter phages Open
Campylobacter jejuni and C. coli are important food-borne pathogens that are widespread in animal husbandry. To combat Campylobacter along the food chain, the application of lytic phages has been shown to be a promising tool. Campylobacter…
View article: Complete Genome Sequence of the Temperate Klebsiella pneumoniae Phage KPP5665-2
Complete Genome Sequence of the Temperate Klebsiella pneumoniae Phage KPP5665-2 Open
We describe here the genome sequence of the novel temperate Klebsiella pneumoniae phage KPP5665-2 isolated from a Klebsiella pneumoniae strain recovered from milk in Germany in 2016. The phage exhibited a narrow host range and a siphovirid…
View article: Approved and novel strategies in diagnostics of rat bite fever and other<i>Streptobacillus</i>infections in humans and animals
Approved and novel strategies in diagnostics of rat bite fever and other<i>Streptobacillus</i>infections in humans and animals Open
Rat bite fever (RBF), a worldwide occurring and most likely under-diagnosed zoonosis caused by Streptobacillus moniliformis, represents the most prominent disease of Streptobacillus infections. Recently, novel members have been described, …