Explanipedia

Insights into the proportion of consultations for musculoskeletal disorders in Dutch general practice: A retrospective cohort study Open

Patrick Krastman, J. van der Lei, J. Runhaar · 2025

Background General practice (GP) care are facing increasing pressure due to a sustained rise in healthcare utilization, partly driven by population ageing and the growing prevalence of chronic conditions such as musculoskeletal disorders (…

Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium Open

Noortje S. Riedstra, Fleur Boel, Marit M. van Buuren, Harbeer Ahedi, Vahid Arbabi , et al. · 2025

Objective To assess the relationship between pincer morphology and incident radiographic hip osteoarthritis (RHOA) and study-specific subgroups. Methods Hips completely free of RHOA at baseline and with follow-up within 4–8 years were draw…

Erratum to ‘Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study’ [Osteoarthritis and Cartilage Open 5 (2023) 100414] Open

William Thompson, Subhashisa Swain, Sizheng Steven Zhao, Anne Kamps, Carol Coupland , et al. · 2025

Hip morphology‐based osteoarthritis risk prediction models: development and external validation using individual participant data from the World COACH Consortium Open

Myrthe A. van den Berg, Fleur Boel, Jinchi Tang, Harbeer Ahedi, Nigel Arden , et al. · 2025

OBJECTIVES: This study aims to develop hip morphology-based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different popu…

Hip morphology‐based osteoarthritis risk prediction models: development and external validation using individual participant data from the World <span>COACH</span> Consortium Open

Myrthe A. van den Berg, Fleur Boel, M.M.A. van Buuren, Noortje S. Riedstra, Jinchi Tang , et al. · 2025

Objectives This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different popul…

Corrigendum to ‘Networking in the osteoarthritis research community in the digital era’ [Osteoarthr Cartil Open 7 (2025) 100650] Open

Rachel K Nelligan, Anca Maglaviceanu, Jocelyn L. Bowden, Jackie L. Whittaker, Tobias Winkler , et al. · 2025

Networking in the osteoarthritis research community in the digital era Open

Rachel K Nelligan, Anca Maglaviceanu, Jocelyn L. Bowden, Jackie L. Whittaker, Tobias Winkler , et al. · 2025

Diagnostic accuracy of history taking, physical examination, and auxiliary examination for thumb osteoarthritis: a systematic review Open

Yisha He, Patrick Krastman, Sita Bierma‐Zeinstra, Gerald Kraan, Nina M.C. Mathijssen , et al. · 2025

Based on few studies, the diagnostic accuracy of history taking and physical examination for thumb OA varied across studies, while knowledge about auxiliary examination was limited. The adduction test, extension test, and metacarpal pressu…

Bidirectional causal relationship between obesity and osteoarthritis: Insights from a two-sample Mendelian randomization study Open

Anne Kamps, J. Runhaar, Katerina Trajanoska, William Thompson, Weiya Zhang , et al. · 2025

Elucidating the initial symptoms and experiences of knee osteoarthritis: An international patient survey Open

Lauren King, Armaghan Mahmoudian, Jean W. Liew, Qiuke Wang, Ian Stanaitis , et al. · 2025

Individuals with knee OA recalled varied knee symptoms within the first year and few sought healthcare. We were unable to ascertain, from the perspective of patients, specific clinical features that indicated they had OA and not another co…

OARSI initiative to develop classification criteria for early-stage symptomatic knee OA (EsSKOA): What conditions should be considered in the differential diagnosis of EsSKOA? Open

Gillian Hawker, Lauren King, Jean W. Liew, Qiuke Wang, Armaghan Mahmoudian , et al. · 2025

The differential diagnosis for EsSKOA in adults presenting with undiagnosed knee symptoms includes symptomatic established radiographic knee OA, patellofemoral pain syndrome, meniscal and collateral ligament injuries, and immune-mediated a…

A Catalog of “Knee Friendly” Aerobic Exercises Developed for Patients With Knee Osteoarthritis: An International Patient Survey Open

Mathilde Espe Pedersen, Tanja Schjødt Jørgensen, Thomas Bandholm, Mathias Ried‐Larsen, Cecilie Bartholdy , et al. · 2025

Objective Aerobic exercise is recommended for the management of knee osteoarthritis (OA), but knee pain is often a barrier for participation. Some types of aerobic exercise may be less painful to undertake than others, though little is kno…

EXPLORING SEX-BASED HIP MORPHOLOGY DIFFERENCES IN YOUNG ADULTS USING AN AUTOMATED 3D METHOD Open

M.A. Kamphuis, E.H. Oei, J. Runhaar, David F. Hanff, Jaap J. Tolk , et al. · 2025

PREVALENCE OF ACETABULAR DYSPLASIA IN 6-YEAR-OLDS IN A GENERAL POPULATION Open

Nadine Hendriks, Fleur Boel, Claudia Lindner, Fernando Rivadeneira, Carl Johan Tiderius , et al. · 2025

Acetabular dysplasia and the risk of developing hip osteoarthritis within 4-8 years; an individual participant data meta-analysis of 18,807 hips from the World COACH consortium. Open

Noortje S. Riedstra, Fleur Boel, M.M.A. van Buuren, Harbeer Ahedi, Vahid Arbabi , et al. · 2024

Do physical or imaging changes explain the effectiveness of progressive tendon loading exercises? A causal mediation analysis of athletes with patellar tendinopathy Open

Jie Deng, J. Runhaar, Stephan J. Breda, E.H. Oei, Denise Eygendaal , et al. · 2024

The beneficial effect of PTLE on patellar tendinopathy was not mediated by changes in physical properties, tendon thickness or degree of neovascularization. Healthcare professionals may consider exploring other potential factors when manag…

Acetabular dysplasia and the risk of developing hip osteoarthritis within 4-8 years: An individual participant data meta-analysis of 18,807 hips from the World COACH consortium Open

Noortje S. Riedstra, Fleur Boel, M.M.A. van Buuren, Harbeer Ahedi, Vahid Arbabi , et al. · 2024

AD was consistently associated with incident RHOA. Explorative analyses show that AD hips in women and age group 61-70 years seem to be more at risk of developing RHOA compared to non-AD hips.

Patient preferences for conservative treatment of shoulder pain: a discrete choice experiment Open

Annelotte H C Versloot, Jorien Veldwijk, Ramon P G Ottenheijm, Marloes Thoomes-de Graaf, Daniëlle van der Windt , et al. · 2024

Background Shoulder pain is common amongst adults, but little is known about patients’ preferences. Objective The aim of this study was to determine patients’ preferences for treatment options offered for shoulder pain in primary care. Met…

The association between cam morphology and hip pain in males and females within 10 years: A national prospective cohort study (CHECK) Open

Jinchi Tang, M.M.A. van Buuren, Fleur Boel, Noortje S. Riedstra, Myrthe A. van den Berg , et al. · 2024

Within this study, no consistent associations were found between cam morphology and hip pain at multiple follow-ups. There might be a weak relationship between cam morphology and hip pain in males, while no such relation was found in femal…

Reliability and agreement of manual and automated morphological radiographic hip measurements Open

Fleur Boel, Noortje S. Riedstra, Jin Tang, David F. Hanff, Harbeer Ahedi , et al. · 2024

The automated algorithm performed equally well compared to manual measurement by trained observers, attesting to its reliability and efficiency in rapidly computing morphological measurements. This validated method can aid clinical practic…

Femoroacetabular impingement syndrome in middle-aged individuals is strongly associated with the development of hip osteoarthritis within 10-year follow-up: a prospective cohort study (CHECK) Open

Rintje Agricola, M.M.A. van Buuren, Joanne L. Kemp, Harrie Weinans, J. Runhaar , et al. · 2024

Objective The objective is to determine the association and absolute risk of femoroacetabular impingement syndrome (FAIS) for the development of radiographic hip osteoarthritis (RHOA). Methods This is a nationwide, multicentre prospective …

Cohort profile: Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) - an international consortium of prospective cohort studies with individual participant data on hip osteoarthritis Open

M.M.A. van Buuren, Noortje S. Riedstra, Myrthe A. van den Berg, Fleur Boel, Harbeer Ahedi , et al. · 2024

PURPOSE: Hip osteoarthritis (OA) is a major cause of pain and disability worldwide. Lack of effective therapies may reflect poor knowledge on its aetiology and risk factors, and result in the management of end-stage hip OA with costly join…

Fluoroscopy: Taking a closer look at joint motion in osteoarthritis Open

N.B.J. Dur, Mariska Wesseling, Erin M. Macri, J. Runhaar · 2024

Knowledge of joint biomechanics is crucial for understanding the pathophysiology of osteoarthritis (OA). Biomechanical changes, especially in early OA, are subtle and therefore require highly accurate and precise ways of measuring joint lo…

Two-year clinical follow-up enhances the diagnosis of early-stage hip osteoarthritis: data from check cohort Open

J. Runhaar, Ömer Özbulut, M. Kloppenburg, Maarten Boers, J. W. J. Bijlsma , et al. · 2024

Objective To provide a set of diagnostic criteria for early-stage hip osteoarthritis (OA) in primary care, using signs and symptoms monitored over 2 years in individuals with hip pain and/or stiffness. Additionally, the study aimed to see …

Incidence of hand and wrist disorders in primary care: a retrospective cohort study Open

Patrick Krastman, Evelien de Schepper, Patrick Bindels, Sita Bierma‐Zeinstra, Gerald Kraan , et al. · 2024

Background The incidence of different types of hand and wrist disorders in primary care is unknown since there are no specific encodings for it. Aim To determine the overall incidence and the incidence of specific types of hand and wrist d…

PLOD2 gene expression in infrapatellar fat pad is correlated with fat mass in obese patients with end-stage knee osteoarthritis Open

J. Van den Langenbergh, Y.M. Bastiaansen-Jenniskens, Gerjo J.V.M. van Osch, J. Runhaar, S. Bierma-Zeinstra , et al. · 2024

Automated radiographic hip morphology measurements: An open-access method Open

Fleur Boel, Suzanne de Vos‐Jakobs, Noortje S. Riedstra, Claudia Lindner, J. Runhaar , et al. · 2024

Cohort profile: Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) – an international consortium of prospective cohort studies with individual participant data on hip osteoarthritis Open

M.M.A. van Buuren, Noortje S. Riedstra, Myrthe A. van den Berg, Fleur Boel, Harbeer Ahedi , et al. · 2024

Purpose Hip osteoarthritis (OA) is a major cause of pain and disability worldwide. Lack of effective therapies may reflect poor knowledge on its aetiology and risk factors, and result in the management of end-stage hip OA with costly joint…

Exercise for knee osteoarthritis pain: Association or causation? Open

Marius Henriksen, J. Runhaar, Aleksandra Turkiewicz, Martin Englund · 2024

Exercise is universally recommended as a primary strategy for the management of knee osteoarthritis (OA) pain. The recommendations are based on results from more than 100 randomized controlled trials (RCTs) that compare exercise to no-atte…

Timing is everything: Towards classification criteria for early-stage symptomatic knee osteoarthritis Open

Armaghan Mahmoudian, Lauren King, Jean W. Liew, Qiuke Wang, C. Thomas Appleton , et al. · 2024

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