José Morais
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View article: Dyadic vs. triadic taxonomy of body representation: A scoping review of brain mapping studies
Dyadic vs. triadic taxonomy of body representation: A scoping review of brain mapping studies Open
Introduction: Body representation refers to how the brain processes information about the body, traditionally categorised by the dyadic taxonomy into body schema and body image. However, the triadic taxonomy proposes the inclusion of the b…
View article: Physiologically Based Biopharmaceutics Model of Apixaban for Biopharmaceutics Risk Assessment
Physiologically Based Biopharmaceutics Model of Apixaban for Biopharmaceutics Risk Assessment Open
Background/Objectives: This study applies a Physiologically Based Biopharmaceutics Modeling (PBBM) framework to predict the bioavailability (BA) and bioequivalence (BE) of apixaban, a borderline BCS Class III/IV drug. It investigates how f…
View article: Mild hypohydration in healthy older adults increases pain-related brain activity without affecting pain perception: a single-blind study
Mild hypohydration in healthy older adults increases pain-related brain activity without affecting pain perception: a single-blind study Open
This study reveals, for the first time, that mild hypohydration equivalent to ∼1% of body mass does not alter pain perception in healthy older adults when they are blinded to their hydration status, despite electroencephalography signals s…
View article: prática teológica humanizadora
prática teológica humanizadora Open
A Laudato Si nos faz perceber que “não podemos deixar de reconhecer que uma verdadeira abordagem ecológica sempre se torna uma abordagem social” que deve integrar a justiça nos debates sobre o meio ambiente, para ouvir tanto o clamor da te…
View article: Da Invenção da Escrita à Alfabetização e à Literacia
Da Invenção da Escrita à Alfabetização e à Literacia Open
Este texto contém uma análise de uma série de questões e de opções relacionadas com a importância da linguagem escrita, da sua aprendizagem e do seu impacto: por um lado, no desenvolvimento das capacidades cognitivas e, subsequentemente, d…
View article: A Two-Way Proposal for the Determination of Bioequivalence for Narrow Therapeutic Index Drugs in the European Union
A Two-Way Proposal for the Determination of Bioequivalence for Narrow Therapeutic Index Drugs in the European Union Open
In the European Union, bioequivalence (BE) for narrow therapeutic index (NTI) drugs is currently demonstrated when the 90% confidence interval for the ratio of the population geometric means of the test and reference products for AUC, and …
View article: Clinical Pharmacology of Vinpocetine: Properties Revisited and Introduction of a Population Pharmacokinetic Model for Its Metabolite, Apovincaminic Acid (AVA)
Clinical Pharmacology of Vinpocetine: Properties Revisited and Introduction of a Population Pharmacokinetic Model for Its Metabolite, Apovincaminic Acid (AVA) Open
This paper examines the use of vinpocetine in the context of clinical pharmacology. The main and active metabolite of vinpocetine is apovincaminic acid (AVA). Due to the scarce information in the literature on AVA pharmacokinetics, we prop…
View article: Predictive Strategies to Reduce the Risk of Rehospitalization with a Focus on Frail Older Adults: A Narrative Review
Predictive Strategies to Reduce the Risk of Rehospitalization with a Focus on Frail Older Adults: A Narrative Review Open
Frailty is a geriatric syndrome that has physical, cognitive, psychological, social, and environmental components and is characterized by a decrease in physiological reserves. Frailty is associated with several adverse health outcomes such…
View article: Development of a Frailty Ladder Using Rasch Analysis: If the Shoe Fits
Development of a Frailty Ladder Using Rasch Analysis: If the Shoe Fits Open
Background The current measurement approach to frailty is to create an index of frailty status, rather than measure it. The purpose of this study is to test the extent to which a set of items identified within the frailty concept fit a hie…
View article: Evaluation of a Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union
Evaluation of a Proposed Approach for the Determination of the Bioequivalence Acceptance Range for Narrow Therapeutic Index Drugs in the European Union Open
Bioequivalence (BE) of products containing narrow therapeutic index (NTI) drugs in the European Union is currently established by demonstrating that the 90% confidence interval for the ratio of the population geometric means of the test co…
View article: The Implementation of a Geriatrics Co-Management Model of Care Reduces Hospital Length of Stay
The Implementation of a Geriatrics Co-Management Model of Care Reduces Hospital Length of Stay Open
(1) Background: Older adults comprise a large proportion of hospitalized patients. Many are frail and require complex care. Geriatrics has developed models of care specific to this inpatient population. Our objective was to demonstrate the…
View article: Applied Psycholinguistics: A Science at the crossroads of cognition and language
Applied Psycholinguistics: A Science at the crossroads of cognition and language Open
Applied Psycholinguistics is a science that engages many others: experimental psychology, cognitive and neurocognitive sciences, linguistics, psychology of language and literacy, and educational and remediation sciences. The present paper’…
View article: The miracle of reading: from written signs to immortal imagery
The miracle of reading: from written signs to immortal imagery Open
In this article, perspectives originated from the Linguistic, Psychology and Educational fields are placed together in order to: 1. Understand the specificities of how reading skills are acquired and how skilled readers' brain processes writ…
View article: Comparison of Different Approaches to Operationalize Fried’s Phenotypic Frailty in the NuAge Cohort
Comparison of Different Approaches to Operationalize Fried’s Phenotypic Frailty in the NuAge Cohort Open
Many operationalization approaches were proposed to identify frailty in older adults. The common use of Fried’s original criteria or other cut-offs based on cohort distribution may not apply in every cohort leading to potential bias in the…
View article: Validation of a Frailty Ladder Using Rasch Analysis: If the Shoe Fits
Validation of a Frailty Ladder Using Rasch Analysis: If the Shoe Fits Open
The current measurement approach to frailty is to classify people on frailty status, rather than measure the degree to which they are frail. Here, we test the extent to which a set of items identified within the frailty concept fits a hier…
View article: Seeing thought in the future: literate forecasting and forecasting literacy
Seeing thought in the future: literate forecasting and forecasting literacy Open
View article: Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men
Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men Open
View article: Health-Related Quality of Life in Older Adults With Acute Cardiovascular Disease Undergoing Early Mobilization
Health-Related Quality of Life in Older Adults With Acute Cardiovascular Disease Undergoing Early Mobilization Open
View article: Revisiting the hypothesis of syndromic frailty: a cross-sectional study of the structural validity of the frailty phenotype
Revisiting the hypothesis of syndromic frailty: a cross-sectional study of the structural validity of the frailty phenotype Open
View article: Motoric cognitive risk syndrome and incident dementia in older adults from the Québec NuAge cohort
Motoric cognitive risk syndrome and incident dementia in older adults from the Québec NuAge cohort Open
Background The co-occurrence of slow walking speed and subjective cognitive complaint (SCC) in non-demented individuals defines motoric cognitive risk syndrome (MCR), which is a pre-dementia stage. There is no information on the associatio…
View article: Seeing thought: a cultural cognitive tool
Seeing thought: a cultural cognitive tool Open
The present paper, which is the first of two twin opinion papers, offers a theoretical approach of literacy and critical literacy in relation to language, thought, and reasoning. Literacy acquisition and practice proceed through two stages…
View article: Impact of literacy on the functional connectivity of vision and language related networks
Impact of literacy on the functional connectivity of vision and language related networks Open
View article: Frailty and adverse outcomes in older adults being discharged from the emergency department: A prospective cohort study
Frailty and adverse outcomes in older adults being discharged from the emergency department: A prospective cohort study Open
View article: Biomarqueurs du syndrome métabolique et signatures métaboliques comme outil de caractérisation d’un vieillissement en santé : une revue systématique
Biomarqueurs du syndrome métabolique et signatures métaboliques comme outil de caractérisation d’un vieillissement en santé : une revue systématique Open
BIEN VIEILLIR AU 21ème SIÈCLE SYMPOSIUM SCIENTIFIQUE 109 - SYNDROME MÉTABOLIQUE ET VIEILLISEMENT
BIEN VIEILLIR AU 21ème SIÈCLE SYMPOSIUM SCIENTIFIQUE 109 - SYNDROME MÉTABOLIQUE ET VIEILLISEMENT
BIEN VIEILLIR AU 21ème SIÈCLE SYMPOS…
BIEN VIEILLIR AU 21ème SIÈCLE SYMPOSIUM SCIENTIFIQUE 109 - SYNDROME MÉTABOLIQUE ET VIEILLISEMENT
BIEN VIEILLIR AU 21ème SIÈCLE SYMPOS…
View article: Particularités du traitement du diabète de type 2 chez la personne âgée
Particularités du traitement du diabète de type 2 chez la personne âgée Open
Particularités du traitement du diabète de type 2 chez la personne âgée. An article from journal Nutrition Science en évolution (Adapter notre pratique pour la prise en charge nutritionnelle du diabète), on Érudit.
View article: Learning to read and its implications on memory and cognition
Learning to read and its implications on memory and cognition Open
Can learning to read change the information process and expand the storage capacity of the human brain? The purpose of this article is to review and to discuss models of memory (working memory, short term and long term memory) in their rel…
View article: DIFFERENT INDICES OF MUSCLE MASS MAY LEAD TO DIFFERENT ASSOCIATIONS WITH THE HOMA-IR SCORE
DIFFERENT INDICES OF MUSCLE MASS MAY LEAD TO DIFFERENT ASSOCIATIONS WITH THE HOMA-IR SCORE Open
Muscle is considered the principal site of glucose uptake and its loss thought to contribute to the development of insulin resistance. The method used to present muscle mass index could account for the discrepancies in establishing the rel…
View article: SERUM BIOMARKERS PREDICTING INSULIN RESISTANCE IN COMMUNITY-DWELLING OLDER ADULTS OF THE NUAGE STUDY
SERUM BIOMARKERS PREDICTING INSULIN RESISTANCE IN COMMUNITY-DWELLING OLDER ADULTS OF THE NUAGE STUDY Open
We aimed to identify predictors of insulin resistance in community-dwelling participants of the Quebec Longitudinal Study on Nutrition and Successful Aging (NuAge). A total of 288 subjects (75.3 ± 4 years) with complete datasets were ident…
View article: A prospective evaluation of the depression–nutrient intake reverse causality hypothesis in a cohort of community-dwelling older Canadians
A prospective evaluation of the depression–nutrient intake reverse causality hypothesis in a cohort of community-dwelling older Canadians Open
Studies have investigated the potential protective effects that diet may have on late-life depression incidence. This disorder can, however, affect the person’s food intake, widely known as the reverse causality hypothesis of depression. T…
View article: The impact of early and late literacy on the functional connectivity of vision and
The impact of early and late literacy on the functional connectivity of vision and Open
Introduction: Learning to read leads to functional and structural changes in the cortical regions related to vision and language. The visual word-form area (VWFA) is though to play a key role in the interaction between these two systems (D…