José Geovanni Romero-Quintana
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View article: Hydrogel-Based Scaffolds: Advancing Bone Regeneration Through Tissue Engineering
Hydrogel-Based Scaffolds: Advancing Bone Regeneration Through Tissue Engineering Open
Bone tissue engineering has emerged as a promising approach to addressing the limitations of traditional bone grafts for repairing bone defects. This regenerative medicine strategy leverages biomaterials, growth factors, and cells to creat…
View article: MLH1 Methylation Status and Microsatellite Instability in Patients with Colorectal Cancer
MLH1 Methylation Status and Microsatellite Instability in Patients with Colorectal Cancer Open
Background/Objectives: The purpose of the current study was to compare the methylation of five regions of the CpG island of MLH1 with the presence of microsatellite instability (MSI) in colorectal cancer (CRC) patients. Methods: The study …
View article: Papillon-Lefèvre Syndrome: 17-Year Dental Follow-Up. Case Report
Papillon-Lefèvre Syndrome: 17-Year Dental Follow-Up. Case Report Open
Introduction: The present report describes the case of a 12-year-old patient with 17-year follow-up who was previously diagnosed with Papillon-Lefèvre Syndrome (PLS), which is a rare autosomal recessive irregularity in the cathepsin C gene…
View article: Twin pregnancy with incomplete hydatidiform mole and coexistent normal live fetus: A case report and review of the literature
Twin pregnancy with incomplete hydatidiform mole and coexistent normal live fetus: A case report and review of the literature Open
Rationale: A pregnancy with incomplete mole is very rare case. Hydatidiform mole (HM) with live fetus is associated with a risk of a wide variety to maternal and fetal complications. The incidence of a normal live fetus and an incomplete m…
View article: The Role of ncRNAs in the Immune Dysregulation of Preeclampsia
The Role of ncRNAs in the Immune Dysregulation of Preeclampsia Open
The main complications causing practically 75% of all maternal deaths are severe bleeding, infections, and high blood pressure during pregnancy (preeclampsia (PE) and eclampsia). The usefulness of ncRNAs as clinical biomarkers has been exp…
View article: Propylene Glycol Potentiates the Inhibitory Action of CTZ Paste on Antibiotic-Resistant Enterococcus faecalis Isolated from the Root Canal: An In Vitro Study
Propylene Glycol Potentiates the Inhibitory Action of CTZ Paste on Antibiotic-Resistant Enterococcus faecalis Isolated from the Root Canal: An In Vitro Study Open
This study aimed to evaluate if the change of vehicle for CTZ (Chloramphenicol, Tetracycline, zinc oxide, and Eugenol) paste improves the inhibition of Enterococcus faecalis in vitro. The vehicles evaluated alone and mixed with CTZ were Eu…
View article: Propylene Glycol Potentiates the Inhibitory Action of Ctz Paste on Antibiotic-Resistant Enterococcus faecalis Isolated from the Root Canal: An In Vitro Study
Propylene Glycol Potentiates the Inhibitory Action of Ctz Paste on Antibiotic-Resistant Enterococcus faecalis Isolated from the Root Canal: An In Vitro Study Open
This study aimed to evaluate if the change of vehicle for CTZ (chloramphenicol, tetracycline, zinc oxide, and eugenol) paste improves the inhibition of Enterococcus faecalis in vitro. The vehicles evaluated alone and mixed with CTZ were eu…
View article: SOX9 knockout decreases stemness properties in colorectal cancer cells
SOX9 knockout decreases stemness properties in colorectal cancer cells Open
Collectively, our findings supply evidence that SOX9 promotes the maintenance of stemness properties in CRC-CSCs.
View article: Biofunctionalization of hydrogel-based scaffolds for vascular tissue regeneration
Biofunctionalization of hydrogel-based scaffolds for vascular tissue regeneration Open
Congenital and acquired tissular losses due to disease or trauma are a major world health problem. Regenerative therapy aims to fix damaged tissues by directing the natural capacity of a host organism to use biofunctionalized artificial ti…
View article: Metabolomic Analysis of Phytochemical Compounds from Agricultural Residues of Eggplant (Solanum melongena L.)
Metabolomic Analysis of Phytochemical Compounds from Agricultural Residues of Eggplant (Solanum melongena L.) Open
The eggplant is a fruit rich in natural products and produced worldwide. However, its cultivation generates a large amount of scarcely used agricultural residues with poor chemical characterization. This study aimed to identify and quantif…
View article: Cytokine-polymorphisms associated with Preeclampsia: A review
Cytokine-polymorphisms associated with Preeclampsia: A review Open
Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of pregnancies and is diagnosed principally when hypertension appears in the second-d half of pregnancy. WHO estimates the incidence of PE to be seven times higher…
View article: First Molecular Characterization of Colletotrichum sp. and Fusarium sp. Isolated from Mangrove in Mexico and the Antagonist Effect of Trichoderma harzianum as an Effective Biocontrol Agent
First Molecular Characterization of Colletotrichum sp. and Fusarium sp. Isolated from Mangrove in Mexico and the Antagonist Effect of Trichoderma harzianum as an Effective Biocontrol Agent Open
The aim of this study was to characterize potential fungal species affecting mangrove species in Mexico. The phytopathogens were identified based on morphological and molecular characteristics using internal transcribed spacer (ITS1/ITS4) …
View article: Serum lipid profile changes and their clinical diagnostic significance in COVID-19 Mexican Patients
Serum lipid profile changes and their clinical diagnostic significance in COVID-19 Mexican Patients Open
Background COVID-19 has been recognized as an emerging and rapidly evolving health condition. For this reason, efforts to determine changes in laboratory parameters of COVID-19 patients as biomarkers are urgent. Lipids are essential compon…
View article: Presence of red complex bacteria and Aggregatibacter actinomycetemcomitans in necrotic primary teeth with periapical abscess in children of Sinaloa, México.
Presence of red complex bacteria and Aggregatibacter actinomycetemcomitans in necrotic primary teeth with periapical abscess in children of Sinaloa, México. Open
Introduction: Pulp necrosis is a common reason of root canal treatment in primary teeth. The red complex and Aggregatibacter actinomycetemcomitans (A.a.) have been associated with pulpal pathologies. Objective: the present study was evalua…
View article: Underexpression of circulating miR-145-5p and miR-133a-3p are associated with breast cancer and immunohistochemical markers
Underexpression of circulating miR-145-5p and miR-133a-3p are associated with breast cancer and immunohistochemical markers Open
We observed an existing association between the molecular characteristics of BC and levels of circulating miR-133a-3p and miR-145-5p, proving the potential role of miRNAs as biomarkers for BC.
View article: Expression of miR-148b-3p is correlated with overexpression of biomarkers in prostate cancer
Expression of miR-148b-3p is correlated with overexpression of biomarkers in prostate cancer Open
Prostate cancer (PCa) is one of the leading causes of death among men. Genes such as PCA3, PSA, and Fra-1 are suggested to serve as potential tools for the detection of PCa, as they are deregulated during this pathology. A similar event oc…
View article: Expression of miR-148b-3p is correlated with overexpression of biomarkers in prostate cancer
Expression of miR-148b-3p is correlated with overexpression of biomarkers in prostate cancer Open
Prostate cancer (PCa) is one of the leading causes of death among men. Genes such as PCA3, PSA, and Fra-1 are suggested to serve as potential tools for the detection of PCa, as they are deregulated during this pathology. A similar event oc…
View article: SOX9 Stem-Cell Factor: Clinical and Functional Relevance in Cancer
SOX9 Stem-Cell Factor: Clinical and Functional Relevance in Cancer Open
Transcriptional and epigenetic embryonic programs can be reactivated in cancer cells. As result, a specific subset of undifferentiated cells with stem-cells properties emerges and drives tumorigenesis. Recent findings have shown that ectod…
View article: Increased Micronuclei Frequency in Oral and Lingual Epithelium of Treated Diabetes Mellitus Patients
Increased Micronuclei Frequency in Oral and Lingual Epithelium of Treated Diabetes Mellitus Patients Open
Diabetes mellitus (DM) is a metabolic disease characterized by persistent high levels of glucose in plasma. Chronic hyperglycemia is thought to increase oxidative stress and the formation of free radicals that in turn damage cells. Thus, w…