José Jerónimo
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View article: ESPWA: a deep learning-enabled tool for precision-based use of endocrine therapy in resource-limited settings
ESPWA: a deep learning-enabled tool for precision-based use of endocrine therapy in resource-limited settings Open
Background Cancer morbidity disproportionately affects patients in low- and middle-income countries (LMICs), where timely and accurate tumor profiling is often nonexistent. Immunohistochemistry-based assessment of estrogen receptor (ER) st…
View article: Generalizable deep neural networks for image quality classification of cervical images
Generalizable deep neural networks for image quality classification of cervical images Open
View article: Analysis of the construction of knowledge in connection with industry
Analysis of the construction of knowledge in connection with industry Open
The term dual training is understood as a type of professional education, where the teaching-learning process takes place in two different places, school and industry (Zamora-Torres et al., 2020). The knowledge management model is approach…
View article: Assessing generalizability of an AI-based visual test for cervical cancer screening
Assessing generalizability of an AI-based visual test for cervical cancer screening Open
A number of challenges hinder artificial intelligence (AI) models from effective clinical translation. Foremost among these challenges is the lack of generalizability, which is defined as the ability of a model to perform well on datasets …
View article: Assessing generalizability of an AI-based visual test for cervical cancer screening
Assessing generalizability of an AI-based visual test for cervical cancer screening Open
A number of challenges hinder artificial intelligence (AI) models from effective clinical translation. Foremost among these challenges is the lack of generalizability, which is defined as the ability of a model to perform well on datasets …
View article: Challenges associated with follow-up care after implementation of an HPV screen-and-treat program with ablative therapy for cervical cancer prevention
Challenges associated with follow-up care after implementation of an HPV screen-and-treat program with ablative therapy for cervical cancer prevention Open
This study highlights the barriers to follow-up after implementation of a primary-level HPV-based screen-and-treat approach. While some barriers that have previously been associated with loss to follow-up were not as prominently observed i…
View article: Implementation of new technologies designed to improve cervical cancer screening and completion of care in low-resource settings: a case study from the Proyecto Precancer
Implementation of new technologies designed to improve cervical cancer screening and completion of care in low-resource settings: a case study from the Proyecto Precancer Open
View article: Knowledge of cytology results affects the performance of colposcopy: a crossover study
Knowledge of cytology results affects the performance of colposcopy: a crossover study Open
Objective To determine whether knowledge of cytology affects the colposcopist’s diagnostic accuracy in the identification of cervical intraepithelial neoplasia grade 2 and worse (≥ CIN2). Method In this cross-over study, healthcare profess…
View article: Cost-effectiveness of cervical cancer screening in women living with HIV in South Africa: A mathematical modeling study
Cost-effectiveness of cervical cancer screening in women living with HIV in South Africa: A mathematical modeling study Open
Background: Women with HIV face an increased risk of human papillomavirus (HPV) acquisition and persistence, cervical intraepithelial neoplasia, and invasive cervical cancer. Our objective was to determine the cost-effectiveness of differe…
View article: Squamocolumnar junction visibility, age, and implications for cervical cancer screening programs
Squamocolumnar junction visibility, age, and implications for cervical cancer screening programs Open
View article: Generalizable deep neural networks for image quality classification of cervical images
Generalizable deep neural networks for image quality classification of cervical images Open
Successful translation of artificial intelligence (AI) models into clinical practice, across clinical domains, is frequently hindered by the lack of image quality control. Diagnostic models are often trained on images with no denotation of…
View article: Author Response: Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy
Author Response: Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy Open
View article: Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy
Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy Open
Background: The HPV-automated visual evaluation (PAVE) Study is an extensive, multinational initiative designed to advance cervical cancer prevention in resource-constrained regions. Cervical cancer disproportionally affects regions with l…
View article: Reproducible and clinically translatable deep neural networks for cervical screening
Reproducible and clinically translatable deep neural networks for cervical screening Open
View article: Reviewer #2 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Reviewer #2 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to reduce cer…
View article: Reviewer #3 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Reviewer #3 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to reduce cer…
View article: Reviewer #1 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Reviewer #1 (Public Review): Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to reduce cer…
View article: Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
Objective To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to …
View article: Author Response: Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Author Response: Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to reduce cer…
View article: “Easy women get it”: pre-existing stigma associated with HPV and cervical cancer in a low-resource setting prior to implementation of an HPV screen-and-treat program
“Easy women get it”: pre-existing stigma associated with HPV and cervical cancer in a low-resource setting prior to implementation of an HPV screen-and-treat program Open
View article: Agreement on Lesion Presence and Location at Colposcopy
Agreement on Lesion Presence and Location at Colposcopy Open
Objectives/purpose The reproducibility and sensitivity of image-based colposcopy is low, but agreement on lesion presence and location remains to be explored. Here, we investigate the interobserver agreement on lesions on colposcopic image…
View article: Recurrence After Biopsy-Confirmed Cervical High-Grade Intraepithelial Lesion Followed by Negative Conization: A Systematic Review and Meta-analysis
Recurrence After Biopsy-Confirmed Cervical High-Grade Intraepithelial Lesion Followed by Negative Conization: A Systematic Review and Meta-analysis Open
The aim of the study is to assess the recurrence rate (as cervical intraepithelial neoplasia 2+ [CIN2+]) in patients who had a confirmed high-grade squamous intraepithelial lesion (CIN2–3) in a cervical biopsy specimen followed by a negati…
View article: Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy
Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy Open
Background: The HPV-automated visual evaluation (PAVE) Study is an extensive, multinational initiative designed to advance cervical cancer prevention in resource-constrained regions. Cervical cancer disproportionally affects regions with l…
View article: Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy
Design of the HPV-Automated Visual Evaluation (PAVE) Study: Validating a Novel Cervical Screening Strategy Open
Objective To describe the HPV-Automated Visual Evaluation (PAVE) Study, an international, multi-centric study designed to evaluate a novel cervical screen-triage-treat strategy for resource-limited settings as part of a global strategy to …
View article: Latin America and the Caribbean Code Against Cancer 1st Edition: Medical interventions including hormone replacement therapy and cancer screening
Latin America and the Caribbean Code Against Cancer 1st Edition: Medical interventions including hormone replacement therapy and cancer screening Open
Prostate, breast, colorectal, cervical, and lung cancers are the leading cause of cancer in Latin America and the Caribbean (LAC) accounting for nearly 50% of cancer cases and cancer deaths in the region. Following the IARC Code Against Ca…
View article: A rapid HPV typing assay to support global cervical cancer screening and risk‐based management: A cross‐sectional study
A rapid HPV typing assay to support global cervical cancer screening and risk‐based management: A cross‐sectional study Open
The World Health Organization recommends human papillomavirus (HPV) testing for cervical screening. Extended genotyping can identify the highest‐risk HPV‐positive women. An inexpensive, rapid, mobile isothermal amplification assay (ScreenF…
View article: Assessing generalizability of an AI-based visual test for cervical cancer screening
Assessing generalizability of an AI-based visual test for cervical cancer screening Open
A number of challenges hinder artificial intelligence (AI) models from effective clinical translation. Foremost among these challenges are: (1) reproducibility or repeatability, which is defined as the ability of a model to make consistent…
View article: Artificial intelligence–based image analysis in clinical testing: lessons from cervical cancer screening
Artificial intelligence–based image analysis in clinical testing: lessons from cervical cancer screening Open
Novel screening and diagnostic tests based on artificial intelligence (AI) image recognition algorithms are proliferating. Some initial reports claim outstanding accuracy followed by disappointing lack of confirmation, including our own ea…
View article: Knowledge of cytology results affects the performance of colposcopy: a crossover study
Knowledge of cytology results affects the performance of colposcopy: a crossover study Open
Objective – To determine whether knowledge of cytology affects the colposcopist’s diagnostic accuracy in the identification of cervical intraepithelial neoplasia grade 2 and worse (≥ CIN2). Method – In this cross-over study, healthcare pro…
View article: Expanding Cervical Cancer Screening in Mozambique: Challenges Associated With Diagnosing and Treating Cervical Cancer
Expanding Cervical Cancer Screening in Mozambique: Challenges Associated With Diagnosing and Treating Cervical Cancer Open
PURPOSE Mozambique has one of the highest burdens of cervical cancer globally. Treatment options are few as most women present with advanced disease, and there are limited trained health professionals and health care resources. The objecti…