Fernando Mendes
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View article: Curcumins‐Loaded ZIF‐8 Nanoparticles‐Embedded Transdermal Polymeric Patches Increase Apoptosis and Reduce Necrosis in a Dose‐Dependent Manner in MCF‐7 Cells
Curcumins‐Loaded ZIF‐8 Nanoparticles‐Embedded Transdermal Polymeric Patches Increase Apoptosis and Reduce Necrosis in a Dose‐Dependent Manner in MCF‐7 Cells Open
Curcumin(Cur)‐loaded zeolitic imidazolate framework‐8 (ZIF‐8) nanoparticles (Cur@ZIF‐8 NPs) were produced to increase the anticancer activity of Cur. Cur@ZIF‐8 NPs were embedded in polycaprolactone (PCL) fibers as transdermal polymeric pat…
View article: HISTÓRIA DO DIREITO E INTELIGÊNCIA ARTIFICIAL
HISTÓRIA DO DIREITO E INTELIGÊNCIA ARTIFICIAL Open
Este artigo trata do papel da História do Direito na formação de professores de Direito no Brasil a partir da reflexão sobre como a articulação entre tradição e inovação pode favorecer uma educação jurídica mais crítica e democrática no pa…
View article: CIÊNCIA DIVERTIDA EM AÇÃO: EXPERIMENTOS INCLUSIVOS PARA EXPLORADORES DO ENSINO FUNDAMENTAL
CIÊNCIA DIVERTIDA EM AÇÃO: EXPERIMENTOS INCLUSIVOS PARA EXPLORADORES DO ENSINO FUNDAMENTAL Open
Playful activities in science teaching can transform learning into a more enjoyable and effective experience, stimulating student interest and participation. The use of games, activities, experiments, and other playful approaches can make …
View article: Effect of Glycerol on Thermal Properties of Galactomannan
Effect of Glycerol on Thermal Properties of Galactomannan Open
Polymeric materials are of great value as they are widely used in everyday society, making it important to synthesize and characterize these materials to enhance them. Galactomannan (Gal), for example, is a neutral natural polymer isolated…
View article: An Update Regarding the Role of Immune Checkpoint Inhibitors in LungCancer – A Systematic Review
An Update Regarding the Role of Immune Checkpoint Inhibitors in LungCancer – A Systematic Review Open
View article: The Role Of Microbiome in Colorectal Cancer – A Systematic Review
The Role Of Microbiome in Colorectal Cancer – A Systematic Review Open
View article: Exploring the Potential of a New Nickel(II):Phenanthroline Complex with L-isoleucine as an Antitumor Agent: Design, Crystal Structure, Spectroscopic Characterization, and Theoretical Insights
Exploring the Potential of a New Nickel(II):Phenanthroline Complex with L-isoleucine as an Antitumor Agent: Design, Crystal Structure, Spectroscopic Characterization, and Theoretical Insights Open
This study presents the synthesis, physicochemical characterization, and biological evaluation of a novel ternary nickel(II) complex with isoleucine and 1,10-phenanthroline ligands, [Ni(Phen)(Ile)2]∙6H2O, designed as a potential antitumor …
View article: Influence of the pH Synthesis of Fe3O4 Magnetic Nanoparticles on Their Applicability for Magnetic Hyperthermia: An In Vitro Analysis
Influence of the pH Synthesis of Fe3O4 Magnetic Nanoparticles on Their Applicability for Magnetic Hyperthermia: An In Vitro Analysis Open
Nanotechnology, specifically magnetic nanoparticles (MNPs), is revolutionizing cancer treatment. Magnetic hyperthermia is a treatment that, using MNPs, can selectively kill cancer cells without causing damage to the surrounding tissues. Ba…
View article: Dielectric Response of Crosslinked Adenanthera pavonina L. Galactomannan in pH-Controlled Medium
Dielectric Response of Crosslinked Adenanthera pavonina L. Galactomannan in pH-Controlled Medium Open
This research investigates the production of galactomannan from Adenanthera pavonina L. in its crude form and its subsequent crosslinking with glutaraldehyde under various pH conditions. The study involved the creation of films and sponges…
View article: The Role of Astrocytes in the Temporoammonic Pathway: Masticatory Behavior as a Neuroprotective Strategy Against Age-Related Cognitive Decline
The Role of Astrocytes in the Temporoammonic Pathway: Masticatory Behavior as a Neuroprotective Strategy Against Age-Related Cognitive Decline Open
Astrocytes undergo phenotypic changes with aging, contributing to neurodegenerative diseases and cognitive impairments in later life. The temporoammonic (TA) pathway terminates at the stratum lacunosum-moleculare (SLM) of the CA1 region, w…
View article: Prescribed Hospital Diet Influence on Dietary Intake of Hospitalised Patients: A Cross-Sectional Study
Prescribed Hospital Diet Influence on Dietary Intake of Hospitalised Patients: A Cross-Sectional Study Open
Background: The dietary intake of hospitalised patients is often compromised during hospitalisation, which can be a causal factor for hospital malnutrition. This is considered a public health problem worldwide and is associated with an inc…
View article: DOENÇA INFLAMATÓRIA INTESTINAL EM FELINO DOMÉSTICO DA RAÇA PERSA: RELATO DE CASO
DOENÇA INFLAMATÓRIA INTESTINAL EM FELINO DOMÉSTICO DA RAÇA PERSA: RELATO DE CASO Open
A doença inflamatória intestinal é uma das patologias mais frequentes na rotina médica felina, sendo um conjunto de distúrbios gastrintestinais idiopáticos e de caráter crônico. A etiopatogenia da doença é diversa, envolvendo complexas int…
View article: Percepção de professores de Biologia da Educação Profissional e Tecnológica sobre a Educação Inclusiva
Percepção de professores de Biologia da Educação Profissional e Tecnológica sobre a Educação Inclusiva Open
Resumo Este artigo tem por objetivo identificar a capacitação de professores de Biologia no ambiente escolar, da Rede Federal de Educação Profissional, Científica e Tecnológica, no que se refere à inclusão de pessoas com deficiência visual…
View article: The Effect of Nutritional Intervention in Nutritional Risk Screening on Hospitalised Lung Cancer Patients
The Effect of Nutritional Intervention in Nutritional Risk Screening on Hospitalised Lung Cancer Patients Open
Background: Lung cancer (LC) patients are prone to suffer from malnutrition. Malnutrition negatively affects patients’ response to therapy, increases the incidence of treatment-related side effects, and decreases survival. Early identifica…
View article: Immunotherapy in gastric cancer—A systematic review
Immunotherapy in gastric cancer—A systematic review Open
Safety analysis showed that immunotherapy was mostly well-tolerated, with manageable adverse events and relatively good safety profiles. Nonetheless, further research is required to understand the mechanisms of tumor resistance better and …
View article: Ressemantizar a presença de mulheres na Educação Profissional e Tecnológica
Ressemantizar a presença de mulheres na Educação Profissional e Tecnológica Open
Este artigo analisa a participação feminina, emoldurada pela desigualdade de gênero, na oferta da Educação Profissional e Tecnológica (EPT) latino-americana e na maior rede dessa oferta do Brasil, representada pelos Institutos Federais (IF…
View article: Ética profissional na educação profissional e tecnológica
Ética profissional na educação profissional e tecnológica Open
O presente artigo tem por objetivo analisar a ética profissional no exercício da docência no âmbito do Ensino Superior na Educação Profissional e Tecnológica (EPT). Foi realizada uma revisão bibliográfica com artigos publicados nas bases d…
View article: Dielectric Characterization of Solutions of Galactomannan Extracted from Adenanthera pavonina L.: Effects of Purification and Ethanol Concentration
Dielectric Characterization of Solutions of Galactomannan Extracted from Adenanthera pavonina L.: Effects of Purification and Ethanol Concentration Open
Galactomannans are polysaccharides obtained from legume seed extraction. They present a chemical structure consisting of D-mannose chains linked by glycosidic bonds and galactose branches. The main focus lies in their use as thickeners in …
View article: Expression of HER2, CD34, and EBV infection in gastric cancer, do they relate?
Expression of HER2, CD34, and EBV infection in gastric cancer, do they relate? Open
Introduction: Gastric cancer (GC), as a multifactorial disease, exhibits a complex pathogenesis, having intra and inter-tumor heterogeneity, challenging the efficacy of current treatments. GC is a major global health problem, and better di…
View article: EXOSTOSE ANULAR INTERFALÂNGICA (RING BONE) EM UM EQUINO DA RAÇA QUARTO DE MILHA- RELATO DE CASO
EXOSTOSE ANULAR INTERFALÂNGICA (RING BONE) EM UM EQUINO DA RAÇA QUARTO DE MILHA- RELATO DE CASO Open
Exostose anular conhecida, como Ring Bone, é uma doença degenerativa que acomete as articulações interfalangeanas dos equinos. Esta gera um crescimento ósseo, que causa dor e claudicação de grau elevado, juntamente com a perda da cartilage…
View article: ANÁLISE MICROBIOLÓGICA EM PONTOS DO FLUXOGRAMA DE PRODUÇÃO DE QUEIJO MINAS FRESCAL
ANÁLISE MICROBIOLÓGICA EM PONTOS DO FLUXOGRAMA DE PRODUÇÃO DE QUEIJO MINAS FRESCAL Open
Embora o Brasil ocupe uma posição beneficiada entre os países produtores de leite e na produção de queijo é de suma importância avaliar as condições higiênicas desses e o modo pelo qual são produzidos. Nesse contexto, o objetivo desse trab…
View article: Self-perception of dual career barriers and athletic identity in student-athletes with disabilities according to disability type and level of professionalization
Self-perception of dual career barriers and athletic identity in student-athletes with disabilities according to disability type and level of professionalization Open
View article: Review of: "Progression-free survival as a primary end-point: Counting the cost"
Review of: "Progression-free survival as a primary end-point: Counting the cost" Open
View article: Review of: "Targeting Cancer Cell Signaling Using Precision Oncology Towards a Holistic Approach to Cancer Therapeutics"
Review of: "Targeting Cancer Cell Signaling Using Precision Oncology Towards a Holistic Approach to Cancer Therapeutics" Open
View article: Cover Image
Cover Image Open
The cover image is based on the Research Article Physical, morphological and bioactive properties of Co–Cr–W–Ta alloys: Influence of insertion of tantalum and surface thermochemical treatment on bioactivity by Beatriz da Silva Batista et a…
View article: Potencialidades e usos da espécie vegetal Cissus Verticillata (l.) Nicolson & C.E. Jarvis na medicina herbal
Potencialidades e usos da espécie vegetal Cissus Verticillata (l.) Nicolson & C.E. Jarvis na medicina herbal Open
View article: Extraction, Purification and Electrical Characterization of Gross Galactomannan and Purified Galactomannan Obtained from <i>Adenanthera pavonina</i> L. Seeds
Extraction, Purification and Electrical Characterization of Gross Galactomannan and Purified Galactomannan Obtained from <i>Adenanthera pavonina</i> L. Seeds Open
Aiming of self‐sustainable production, the search for biodegradable and biocompatible materials has brought with it the need to know the physicochemical and dielectric characteristics of polysaccharide‐based composite structures, which can…
View article: Biomarkers of resistance mechanisms in innovative lung cancer treatments - A systematic Review
Biomarkers of resistance mechanisms in innovative lung cancer treatments - A systematic Review Open
Review question / Objective: This systematic review aims to provide an overview of the immunotherapy resistance mechanisms and identify potential biomarkers associated with immunotherapy response in NSCLC, as well as examine new treatment …
View article: Immunotherapy in Head and Neck Cancer When, How, and Why?
Immunotherapy in Head and Neck Cancer When, How, and Why? Open
Head and neck cancer (HNC) is one of the most common cancers worldwide. Alcohol and tobacco consumption, besides viral infections, are the main risk factors associated with this cancer. When diagnosed in advanced stages, HNC patients prese…
View article: Immunotherapy in Head and Neck Cancer When, How and Why?
Immunotherapy in Head and Neck Cancer When, How and Why? Open
Review question / Objective: In patients with advanced or recurrent/metastatic head and neck cancer, immunotherapy alone or in combination with radiotherapy and chemotherapy, compared with standard therapy, can promote increased overall su…