José M. Miró
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View article: Evolution of kidney function after five years of follow-up in a large Spanish cohort of patients with HIV: Risk factors for progression
Evolution of kidney function after five years of follow-up in a large Spanish cohort of patients with HIV: Risk factors for progression Open
Background Antiretroviral therapy has improved life expectancy in HIV patients; however the increase in longevity has led to comorbidities, with chronic kidney disease (CKD) being especially concerning. CKD may evolve into end-stage kidney…
View article: Risk of Cancer in People With Human Immunodeficiency Virus Experiencing Varying Degrees of Immune Recovery With Sustained Virological Suppression on Antiretroviral Treatment for More Than 2 Years: An International, Multicenter, Observational Cohort
Risk of Cancer in People With Human Immunodeficiency Virus Experiencing Varying Degrees of Immune Recovery With Sustained Virological Suppression on Antiretroviral Treatment for More Than 2 Years: An International, Multicenter, Observational Cohort Open
Background The impact of long-term virological suppression (VS) and CD4 count recovery on non–AIDS-defining cancers (NADCs) is unclear. We determined whether poor immune recovery was associated with incident cancer risk in people with huma…
View article: HIV-Tat upregulates the expression of senescence biomarkers in CD4+ T-cells
HIV-Tat upregulates the expression of senescence biomarkers in CD4+ T-cells Open
Introduction Current antiretroviral therapy (ART) for HIV infection reduces plasma viral loads to undetectable levels and has increased the life expectancy of people with HIV (PWH). However, this increased lifespan is accompanied by signs …
View article: Key priorities for the implementation of the 2023 ESC Guidelines for the management of endocarditis in low-resource settings
Key priorities for the implementation of the 2023 ESC Guidelines for the management of endocarditis in low-resource settings Open
European Society of Cardiology (ESC) Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible for best practices to be followed, however, …
View article: Real-world evidence of dalbavancin effectiveness as consolidation therapy in infective endocarditis due to Enterococcus spp.
Real-world evidence of dalbavancin effectiveness as consolidation therapy in infective endocarditis due to Enterococcus spp. Open
View article: Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT)
Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT) Open
Background This study assessed the pharmacokinetic interactions between dolutegravir (DTG)-based antiretroviral therapy (ART) and immunosuppressants in solid organ transplantation (SOT) recipients with HIV and ART safety. Methods A phase I…
View article: Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial
Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial Open
View article: Activating Thermoplastic Polyurethane Surfaces with Poly(ethylene glycol)-Based Recombinant Human α-Defensin 5 Monolayers for Antibiofilm Activity
Activating Thermoplastic Polyurethane Surfaces with Poly(ethylene glycol)-Based Recombinant Human α-Defensin 5 Monolayers for Antibiofilm Activity Open
Addressing multidrug-resistant microbial infections linked to implantable biomedical devices is an urgent need. In recent years, there has been an active exploration of different surface coatings to prevent and combat drug-resistant microb…
View article: Impact of Antithrombotic Therapy on Intracranial Hemorrhage in Infective Endocarditis: A Multicenter Prospective Cohort Study
Impact of Antithrombotic Therapy on Intracranial Hemorrhage in Infective Endocarditis: A Multicenter Prospective Cohort Study Open
View article: In Vitro Activity of Ampicillin Plus Ceftriaxone Against Non-faecalis and Non-faecium Enterococcal Isolates With/Without VanC Phenotype: Clinical Implications for Infective Endocarditis
In Vitro Activity of Ampicillin Plus Ceftriaxone Against Non-faecalis and Non-faecium Enterococcal Isolates With/Without VanC Phenotype: Clinical Implications for Infective Endocarditis Open
(1) Background: Alternative antibiotics are needed to treat infective endocarditis (IE) caused by non-faecalis/non-faecium enterococci; we aimed to assess the in vitro activity of ampicillin plus ceftriaxone (AMP + CTR) against these enter…
View article: Efficacy and safety of antistaphylococcal penicillin or cephazolin-based combinations versus monotherapy for methicillin-susceptible Staphylococcus aureus infective endocarditis: A propensity score analysis of nationwide prospective cohort
Efficacy and safety of antistaphylococcal penicillin or cephazolin-based combinations versus monotherapy for methicillin-susceptible Staphylococcus aureus infective endocarditis: A propensity score analysis of nationwide prospective cohort Open
Antibiotic combinations for patients with native valve left-sided MSSA endocarditis did not improve patient's outcomes. Drug-related adverse events were more frequent in combination patients.
View article: Burden of liver steatosis and liver fibrosis in a large cohort of people living with <scp>HIV</scp>
Burden of liver steatosis and liver fibrosis in a large cohort of people living with <span>HIV</span> Open
Background Liver steatosis (LS) and liver fibrosis (LF) can increase the risk of cardiovascular disease in people with HIV, but their prevalence and associated factors are poorly understood. This study aimed to assess the prevalence of and…
View article: HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983–2015
HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983–2015 Open
Introduction HIV replication leads to a change in lymphocyte phenotypes that impairs immune protection against opportunistic infections. We examined current HIV replication as an independent risk factor for tuberculosis (TB). Methods We in…
View article: Clinical features and prognosis of prosthetic valve endocarditis due to Staphylococcus aureus
Clinical features and prognosis of prosthetic valve endocarditis due to Staphylococcus aureus Open
View article: #3080 Response to mRNA SARS-CoV-2 vaccination in kidney transplant recipients with HIV
#3080 Response to mRNA SARS-CoV-2 vaccination in kidney transplant recipients with HIV Open
Background and Aims No data exists on humoral or cellular responses to mRNA vaccines in kidney transplant recipients (KTR) with HIV. We compared these responses in HIV-positive and negative KTR, as well as in people living with HIV (PLWH) …
View article: Clinical features and prognosis of prosthetic valve endocarditis due to Staphylococcus aureus
Clinical features and prognosis of prosthetic valve endocarditis due to Staphylococcus aureus Open
Purpose. Staphylococcus aureus prosthetic valve endocarditis (SAPVE) is a serious infection with high mortality. The main objective of this study was to identify factors associated with in-hospital mortality. Methods. From January 2008 to …
View article: <scp>SARS‐CoV</scp>‐2 testing, positivity, and factors associated with COVID‐19 among people with <scp>HIV</scp> across Europe in the multinational <scp>EuroSIDA</scp> cohort
<span>SARS‐CoV</span>‐2 testing, positivity, and factors associated with COVID‐19 among people with <span>HIV</span> across Europe in the multinational <span>EuroSIDA</span> cohort Open
Background Although people with HIV might be at risk of severe outcomes from infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2; coronavirus 2019 [COVID‐19]), regional and temporal differences in SARS‐CoV‐2 testing …
View article: Epidemiology and Risk Factors of Mycotic Aneurysm in Patients With Infective Endocarditis and the Impact of its Rupture in Outcomes. Analysis of a National Prospective Cohort
Epidemiology and Risk Factors of Mycotic Aneurysm in Patients With Infective Endocarditis and the Impact of its Rupture in Outcomes. Analysis of a National Prospective Cohort Open
Background Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied. Objectives To determine the incidence and factors associated with MA presence and rupt…
View article: External Validation of the 2023 Duke–International Society for Cardiovascular Infectious Diseases Diagnostic Criteria for Infective Endocarditis
External Validation of the 2023 Duke–International Society for Cardiovascular Infectious Diseases Diagnostic Criteria for Infective Endocarditis Open
Background The 2023 Duke–International Society of Cardiovascular Infectious Diseases (ISCVID) criteria for infective endocarditis (IE) were introduced to improve classification of IE for research and clinical purposes. External validation …
View article: Reply to Villareal and El-Altrouni: Clarifications of the 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis
Reply to Villareal and El-Altrouni: Clarifications of the 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis Open
Journal Article Corrected proof Reply to Villareal and El-Altrouni: Clarifications of the 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis Get access Vance G Fowler, Jr, Vance G Fow…
View article: Gut Microbiota Recovery in Late Hiv-1 Presenters Initiating First-Line Dolutegravir-Based Antiretroviral Therapy: Results from a 2-Year, Open-Label, Randomized Clinical Trial
Gut Microbiota Recovery in Late Hiv-1 Presenters Initiating First-Line Dolutegravir-Based Antiretroviral Therapy: Results from a 2-Year, Open-Label, Randomized Clinical Trial Open
View article: Endocarditis por Neisseria. presentación de tres casos y revisión de la literatura (2000-2023)
Endocarditis por Neisseria. presentación de tres casos y revisión de la literatura (2000-2023) Open
View article: Gut Microbiota Recovery in Late Hiv-1 Presenters Initiating First-Line Dolutegravir-Based Antiretroviral Therapy: Results from a 2-Year, Open-Label, Randomized Clinical Trial
Gut Microbiota Recovery in Late Hiv-1 Presenters Initiating First-Line Dolutegravir-Based Antiretroviral Therapy: Results from a 2-Year, Open-Label, Randomized Clinical Trial Open
View article: Eficacia in vitro de nuevas pautas antibióticas orales en la endocarditis infecciosa (EI) por Enterococcus faecalis
Eficacia in vitro de nuevas pautas antibióticas orales en la endocarditis infecciosa (EI) por Enterococcus faecalis Open
View article: Estudio in vitro de la eficacia de las nuevas combinaciones orales en el tratamiento ambulatorio de la ei por S. aureus sensible a la meticilina
Estudio in vitro de la eficacia de las nuevas combinaciones orales en el tratamiento ambulatorio de la ei por S. aureus sensible a la meticilina Open
View article: Comparative Analysis of Primary and Monovalent Booster SARS-CoV-2 Vaccination Coverage in Adults with and without HIV in Catalonia, Spain
Comparative Analysis of Primary and Monovalent Booster SARS-CoV-2 Vaccination Coverage in Adults with and without HIV in Catalonia, Spain Open
People with HIV (PWH) may be more susceptible to SARS-CoV-2 infection and worse clinical outcomes. We investigated the disparity in SARS-CoV-2 vaccination coverage between PWH and those without HIV (PWoH) in Catalonia, Spain, assessing pri…
View article: Measures of Longitudinal Immune Dysfunction and Risk of AIDS and Non-AIDS Defining Malignancies in Antiretroviral-Treated People With Human Immunodeficiency Virus
Measures of Longitudinal Immune Dysfunction and Risk of AIDS and Non-AIDS Defining Malignancies in Antiretroviral-Treated People With Human Immunodeficiency Virus Open
Background Human immunodeficiency virus (HIV) infection leads to chronic immune activation/inflammation that can persist in virally suppressed persons on fully active antiretroviral therapy (ART) and increase risk of malignancies. The prog…
View article: Issue Information
Issue Information Open
View article: Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort
Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort Open
Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective.
View article: Mpox: Clinical Outcomes and Impact of Vaccination in People with and without HIV: A Population-Wide Study
Mpox: Clinical Outcomes and Impact of Vaccination in People with and without HIV: A Population-Wide Study Open
We investigated differences in mpox clinical outcomes in people with HIV (PWH) and without HIV (PWoH) and the impact of vaccination in Catalonia, Spain. We used surveillance data and the PISCIS HIV cohort. We included all confirmed mpox ca…