José Manuel Aramendía
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View article: 60eP Impact of integrating next-generation sequencing (NGS) with immunohistochemistry (IHC) for risk stratification and treatment in endometrial cancer
60eP Impact of integrating next-generation sequencing (NGS) with immunohistochemistry (IHC) for risk stratification and treatment in endometrial cancer Open
View article: 103P Real-world tumor-based next-generation sequencing in ovarian cancer: Descriptive analysis
103P Real-world tumor-based next-generation sequencing in ovarian cancer: Descriptive analysis Open
View article: Prognostic value of systemic inflammation response indexes obtained from the complete blood count in patients treated for advanced ovarian carcinoma in front line
Prognostic value of systemic inflammation response indexes obtained from the complete blood count in patients treated for advanced ovarian carcinoma in front line Open
View article: Dietary carbohydrate quality index and incidence of obesity-related cancers in the “Seguimiento Universidad De Navarra” (SUN) prospective cohort
Dietary carbohydrate quality index and incidence of obesity-related cancers in the “Seguimiento Universidad De Navarra” (SUN) prospective cohort Open
Summary Purpose The quality, rather than the quantity, of carbohydrate intake may play a major role in the etiology of obesity-related cancers (ORCs). We assessed the association between a previously defined carbohydrate quality index (CQI…
View article: 1755P Carbohydrate quality index and incidence of obesity-related cancers: The Seguimiento Universidad de Navarra (SUN) project
1755P Carbohydrate quality index and incidence of obesity-related cancers: The Seguimiento Universidad de Navarra (SUN) project Open
View article: 232P Identification of ‘secondary’ germline cancer predisposition variants from somatic tumour testing: Should we evolve towards universal screening?
232P Identification of ‘secondary’ germline cancer predisposition variants from somatic tumour testing: Should we evolve towards universal screening? Open
View article: 2022-RA-1309-ESGO Analysis of the prognostic value of systemic inflammation markers obtained from the complete blood count in patients treated for advanced ovarian carcinoma at the CUN in the period 2000–2015
2022-RA-1309-ESGO Analysis of the prognostic value of systemic inflammation markers obtained from the complete blood count in patients treated for advanced ovarian carcinoma at the CUN in the period 2000–2015 Open
View article: A pharmacometrics model to define docetaxel target in early breast cancer
A pharmacometrics model to define docetaxel target in early breast cancer Open
Aims We aimed to study the relation between pharmacokinetics (PK) and pharmacodynamics (PD) of docetaxel in early breast cancer and recommend a target exposure. Methods A PK/PD study was performed in 27 early breast cancer patients treated…
View article: A Fibrosis Biomarker Early Predicts Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy
A Fibrosis Biomarker Early Predicts Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy Open
Anthracycline-based cancer chemotherapy (ACC) causes myocardial fibrosis, a lesion contributing to left ventricular dysfunction (LVD). We investigated whether the procollagen-derived type-I C-terminal-propeptide (PICP): (1) associates with…
View article: 589 Variables that modify the survival after recurrence in patients with early cervical cancer
589 Variables that modify the survival after recurrence in patients with early cervical cancer Open
Introduction/Background* The primary objective of this project was to identify the independent clinical-pathological variables associated with the death after relapse in patients with stage IB1 cervical cancer who underwent radical hystere…
View article: 612 Diagnostic accuracy of PET/CT in the detection of retroperitoneal lymph node in patients with high-risk endometrial cancer: Meta-analysis
612 Diagnostic accuracy of PET/CT in the detection of retroperitoneal lymph node in patients with high-risk endometrial cancer: Meta-analysis Open
Introduction/Background* The aim of this study was to assess the diagnostic accuracy of preoperative 18F-FDG PET or PET/CT in detecting retroperitoneal lymph node (pelvic lymph node and para-aortic lymph node) metastasis in pati…
View article: 779 Surgery in cervical cancer observational prospective (SUCCOP), an ESGO survey: is it a place for another european prospective study?
779 Surgery in cervical cancer observational prospective (SUCCOP), an ESGO survey: is it a place for another european prospective study? Open
Introduction/Background* The study attempts to understand the impact of the different retrospective studies conducted by the SUCCOR group on the daily surgical practice among ESGO members. We intend to propose a new observational prospecti…
View article: 445 Pattern of relapse in patients with stage IB1 cervical cancer after radical hysterectomy. MIS vs Open Approach. Systematic review and Meta- analysis
445 Pattern of relapse in patients with stage IB1 cervical cancer after radical hysterectomy. MIS vs Open Approach. Systematic review and Meta- analysis Open
Introduction/Background* After the LACC trial, SUCCOR study and other studies, we know that patients who have undergone Minimally Invasive Surgery for cervical cancer have worse outcomes, but today we really don't know if the surgical appr…
View article: The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes Open
Background Adoptive immunotherapy with tumour-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as PD-1, for tumour-specific T-cell enrichment, and the identification of predictive factors that help identif…
View article: Increased Serum Procollagen type I C-terminal Propeptide Levels are Associated with Left Ventricular Dysfunction in Patients Treated with Anthracycline-based Cancer Chemotherapy
Increased Serum Procollagen type I C-terminal Propeptide Levels are Associated with Left Ventricular Dysfunction in Patients Treated with Anthracycline-based Cancer Chemotherapy Open
Background Anthracycline-based cancer chemotherapy (ACC) has been related to myocardial interstitial fibrosis (MIF), a lesion contributing to left ventricular dysfunction (LVD). We investigated whether biomarker-assessed MIF was associated…
View article: Increased Serum Procollagen Type I C-terminal Propeptide Levels are Associated with Subclinical Left Ventricular Dysfunction in Patients with Breast Cancer Treated with Anthracycline-Based Cancer Chemotherapy
Increased Serum Procollagen Type I C-terminal Propeptide Levels are Associated with Subclinical Left Ventricular Dysfunction in Patients with Breast Cancer Treated with Anthracycline-Based Cancer Chemotherapy Open
Background Anthracycline-based cancer chemotherapy (ACC) has been related to myocardial interstitial fibrosis (MIF), a lesion contributing to left ventricular dysfunction (LVD). We investigated whether biomarker-assessed MIF was associated…
View article: OC-1057: Phase I/II trial of ultra-APBI on early breast cancer (4f-APBI): Initial feasibility results.
OC-1057: Phase I/II trial of ultra-APBI on early breast cancer (4f-APBI): Initial feasibility results. Open
View article: The mutational load and a T-cell inflamed tumor phenotype identify ovarian cancer patients rendering tumor-reactive T cells from PD-1+ tumor-infiltrating lymphocytes
The mutational load and a T-cell inflamed tumor phenotype identify ovarian cancer patients rendering tumor-reactive T cells from PD-1+ tumor-infiltrating lymphocytes Open
Background: Adoptive immunotherapy with tumor-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as programmed cell death protein 1 (PD-1), for tumor-specific T-cell enrichment, as well as predictive biomark…
View article: Mediterranean dietary pattern is associated with lower incidence of premenopausal breast cancer in the Seguimiento Universidad de Navarra (SUN) Project
Mediterranean dietary pattern is associated with lower incidence of premenopausal breast cancer in the Seguimiento Universidad de Navarra (SUN) Project Open
Objective: Due to the growing interest in the role of dietary patterns (DPs) on chronic diseases, we assessed the association between a posteriori identified DPs in the Seguimiento Universidad de Navarra (SUN) Project – a prospective cohor…
View article: The impact of secondary cytoreductive surgery on survival in first recurrence of platinum sensitive epithelial ovarian cancer
The impact of secondary cytoreductive surgery on survival in first recurrence of platinum sensitive epithelial ovarian cancer Open
Objective: Analyze the effect on survival of secondary cytoreduction surgery (SCS) in treatment of first recurrence platinumsensitive epithelial ovarian cancer (REOC). \nMethods: Retrospective analysis of patients with first REOC who had p…
View article: Total polyphenol intake and breast cancer risk in the Seguimiento Universidad de Navarra (SUN) cohort
Total polyphenol intake and breast cancer risk in the Seguimiento Universidad de Navarra (SUN) cohort Open
Polyphenols are a wide family of phytochemicals present in diverse foods. They might play a role in cancer development and progression. In vivo and in vitro studies have suggested beneficial properties and potential mechanisms. We aimed to…
View article: Perioperative high-dose-rate brachytherapy in locally advanced and recurrent gynecological cancer: Final results of a Phase II trial
Perioperative high-dose-rate brachytherapy in locally advanced and recurrent gynecological cancer: Final results of a Phase II trial Open
View article: Previous immunotherapy treatments may improve tumor responses with subsequent chemotherapy regimens
Previous immunotherapy treatments may improve tumor responses with subsequent chemotherapy regimens Open
Background: First line therapies usually induce the longest progression free survival (PFS) in advanced/metastatic cancer as compared to subsequent lines of treatment. However, immunotherapy (IT) due to its mechanisms of action could influ…
View article: P01.096 Hypofractionated radiotherapy and temozolomide in patients with glioblastoma and poor prognostic factors other than age - is it worth it?
P01.096 Hypofractionated radiotherapy and temozolomide in patients with glioblastoma and poor prognostic factors other than age - is it worth it? Open
The impact of hypofractionated radiation therapy (HFRT) in elderly glioblastoma patients has recently been investigated, aiming to reduce the overall treatment time in this poor-prognosis group. There is evidence supporting that HFRT is co…
View article: Quimioterapia intensiva en el tratamiento de pacientes con cáncer de mama metastásico
Quimioterapia intensiva en el tratamiento de pacientes con cáncer de mama metastásico Open
Propósito: Estudio fase 11 con quimioterapia intensiva y soporte con células progenitoras autólogas obtenidas de la sangre en pacientes con cáncer de mama metastásico.
Métodos: Tratamos 49 pacientes con una pauta de dos agentes citotóx…
View article: Results of two sequential phase II studies of interleukin-2 (IL2) in metastatic renal cell carcinoma and melanoma: high-dose continuous intravenous IL2 infusion and subcutaneous IL2 administration in combination with alpha interferon
Results of two sequential phase II studies of interleukin-2 (IL2) in metastatic renal cell carcinoma and melanoma: high-dose continuous intravenous IL2 infusion and subcutaneous IL2 administration in combination with alpha interferon Open
se presentan los resultados de dos estudios secuenciales, el primero con dosis altas de interleuquina-2 en infusión intravenosa continua y el segundo con IL2 subcutánea e interferón alfa (IFN alfa), en pacientes con melanoma y carcinoma re…
View article: Tumores germinales avanzados de testículo: experiencia clínica con cisplatino, bleomicina y vinblastina (PVB) o etoposido (BEP)
Tumores germinales avanzados de testículo: experiencia clínica con cisplatino, bleomicina y vinblastina (PVB) o etoposido (BEP) Open
Treinta enfermos con tumores testiculares avanzados fueron tratados con PVB o BEP. Ninguno recibió previamente tratamiento citostático. Se practicó citorreducción tumoral de enfermedad "bulky" antes de la quimioterapia en cuatro pacientes …