José Marreiro de Sales-Neto
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View article: Cardiotonic Steroids as a Potential Novel Approach for Immunomodulation in Inflammatory Bowel Disease
Cardiotonic Steroids as a Potential Novel Approach for Immunomodulation in Inflammatory Bowel Disease Open
Inflammatory bowel disease (IBD) is a chronic condition that significantly impairs the quality of life of millions of individuals. The pathogenesis of IBD is closely linked to dysbiosis of microbiota and the activation of various inflammat…
View article: Patulin inhibits LPS-induced nitric oxide production by suppressing MAPKs signaling pathway
Patulin inhibits LPS-induced nitric oxide production by suppressing MAPKs signaling pathway Open
Patulin (PAT) is a natural product isolated from several species of fungi. Here, we evaluated the effect of PAT (62.5–4,000 ng/ml) in lipopolysaccharide (LPS)-activated murine peritoneal macrophages. Cell viability assay showed that PAT at…
View article: Neutrophils and COVID-19: The road so far
Neutrophils and COVID-19: The road so far Open
View article: Corrigendum: Much More than a Cardiotonic Steroid: Modulation of Inflammation by Ouabain
Corrigendum: Much More than a Cardiotonic Steroid: Modulation of Inflammation by Ouabain Open
[This corrects the article on p. 895 in vol. 8, PMID: 29176951.].
View article: Much More than a Cardiotonic Steroid: Modulation of Inflammation by Ouabain
Much More than a Cardiotonic Steroid: Modulation of Inflammation by Ouabain Open
Since the discovery of ouabain as a cardiotonic steroid hormone present in higher mammals, research about it has progressed rapidly and several of its physiological and pharmacological effects have been described. Ouabain can behave as a s…
View article: Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome
Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome Open
The intimate interplay between immune system, metabolism, and gut microbiota plays an important role in controlling metabolic homeostasis and possible obesity development. Obesity involves impairment of immune response affecting both innat…