Josef Getachew
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View article: The Role of α-Synuclein–DNAJB6b Coaggregation in Amyloid Suppression
The Role of α-Synuclein–DNAJB6b Coaggregation in Amyloid Suppression Open
Chaperones may retard the aggregation of other proteins and increase their solubility. An important goal is a thermodynamic understanding of such an action. Here, the chaperone DNAJB6b (JB6) is found to suppress amyloid formation of the pr…
View article: On the reversibility of amyloid fibril formation
On the reversibility of amyloid fibril formation Open
Amyloids are elongated supramolecular protein self-assemblies. Their formation is a non-covalent assembly process and as such is fully reversible. Amyloid formation is associated with several neurodegenerative diseases, and the reversibili…