Josef Goding
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View article: Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies
Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies Open
Bionic implants are increasingly used to restore neural function yet, achieving a chronically stable neural interface remains challenging. Biohybrid neurotechnologies aim to overcome this limitation by integrating living tissue or other bi…
View article: Neuromodulation of a peripheral nerve using fully polymeric cuff electrodes: Understanding predictability of selective stimulation
Neuromodulation of a peripheral nerve using fully polymeric cuff electrodes: Understanding predictability of selective stimulation Open
Peripheral nerve stimulation (PNS) offers therapeutic benefits across numerous clinical applications but suffers from limitations in high resolution spatial selectivity, especially in mixed nerves. This study presents a fully polymeric, tr…
View article: P07.15.A ELECTROACTIVE DRUG DELIVERY DEVICE FOR TARGETED INTRATUMORAL THERAPY
P07.15.A ELECTROACTIVE DRUG DELIVERY DEVICE FOR TARGETED INTRATUMORAL THERAPY Open
BACKGROUND Despite recent advances in cancer therapeutics, the prognosis for glioblastoma multiforme (GBM) remains exceptionally poor, stemming from the limited ability of systemically administered chemotherapeutics to cross the blood brai…
View article: Astrocyte-Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies
Astrocyte-Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies Open
Bionic implants are increasingly used to restore neural function yet achieving a chronically stable neural interface remains challenging. Biohybrid neurotechnologies aim to overcome this limitation by integrating living tissue components t…
View article: “Spin‐Rinse and Repeat”: Facile Processing to Improve Cytocompatibility of Poly(3,4‐Ethyelenedioxythiophene): Polystyrene Sulfonate Composites for Bioelectronics
“Spin‐Rinse and Repeat”: Facile Processing to Improve Cytocompatibility of Poly(3,4‐Ethyelenedioxythiophene): Polystyrene Sulfonate Composites for Bioelectronics Open
Conductive polymers, such as poly(3,4‐ethyelenedioxythiophene):polystyrene sulfonate (PEDOT:PSS), offer exciting prospects in organic bioelectronic applications. Translation of commercially available formulations of PEDOT:PSS is hampered b…
View article: Synthesis and Polymerization of Thiophene‐Bearing 2‐Oxazolines and 2‐Oxazines
Synthesis and Polymerization of Thiophene‐Bearing 2‐Oxazolines and 2‐Oxazines Open
Intrinsically conductive polymers have garnered a great deal of attention for use in medical and bioelectronic applications. Despite this, challenges associated with the mechanical stability, processability, and fabrication of conducting p…
View article: Multi-layered electrode constructs for neural tissue engineering
Multi-layered electrode constructs for neural tissue engineering Open
The study describes the development of a multi-layered electrode coating that was electrochemically characterised. A numerical model of the electric field was developed, and astrocytes were encapsulated within the biosynthetic layer.
View article: Guest Editorial: Implantable bioelectronics
Guest Editorial: Implantable bioelectronics Open
The realm of implantable bioelectronics represents a frontier in medical science, merging technology, biology, and medicine to innovate treatments that enhance, restore, or monitor physiological functions. This field has yielded devices li…
View article: Polymer Bioelectronics: A Solution for Both Stimulating and Recording Electrodes
Polymer Bioelectronics: A Solution for Both Stimulating and Recording Electrodes Open
The advent of closed‐loop bionics has created a demand for electrode materials that are ideal for both stimulating and recording applications. The growing complexity and diminishing size of implantable devices for neural interfaces have mo…
View article: Injectable conductive hydrogel electrodes for minimally invasive neural interfaces
Injectable conductive hydrogel electrodes for minimally invasive neural interfaces Open
An injectable PEDOT:PSS/acetic acid-based hydrogel was formulated with mechanical and electrochemical properties being independently tuneable. The material was characterised in vitro and ex vivo , with prospective applications in neural in…
View article: Controlled electroactive release from solid-state conductive elastomer electrodes
Controlled electroactive release from solid-state conductive elastomer electrodes Open
View article: Surface electromyography using dry polymeric electrodes
Surface electromyography using dry polymeric electrodes Open
Conventional wet Ag/AgCl electrodes are widely used in electrocardiography, electromyography (EMG), and electroencephalography (EEG) and are considered the gold standard for biopotential measurements. However, these electrodes require subs…
View article: Flexible Networks of Patterned Conducting Polymer Nanowires for Fully Polymeric Bioelectronics
Flexible Networks of Patterned Conducting Polymer Nanowires for Fully Polymeric Bioelectronics Open
Patterning of conducting polymers (CPs) into fully functioning devices remains a challenge for the creation of polymeric bioelectronics. Presently, the most successful method for patterning CPs is preprocess blending with structural compon…
View article: Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces
Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces Open
Brain–computer interfaces (BCIs) provide bidirectional communication between the brain and output devices that translate user intent into function. Among the different brain imaging techniques used to operate BCIs, electroencephalography (…
View article: The influence of physicochemical properties on the processibility of conducting polymers: A bioelectronics perspective
The influence of physicochemical properties on the processibility of conducting polymers: A bioelectronics perspective Open
Conducting polymers (CPs) possess unique electrical and electrochemical properties and hold great potential for different applications in the field of bioelectronics. However, the widespread implementation of CPs in this field has been cri…
View article: Self-Assembling Hydrogel Structures for Neural Tissue Repair
Self-Assembling Hydrogel Structures for Neural Tissue Repair Open
Hydrogel materials have been employed as biological scaffolds for tissue regeneration across a wide range of applications. Their versatility and biomimetic properties make them an optimal choice for treating the complex and delicate milieu…
View article: Stretchable, Fully Polymeric Electrode Arrays for Peripheral Nerve Stimulation
Stretchable, Fully Polymeric Electrode Arrays for Peripheral Nerve Stimulation Open
There is a critical need to transition research level flexible polymer bioelectronics toward the clinic by demonstrating both reliability in fabrication and stable device performance. Conductive elastomers (CEs) are composites of conductiv…
View article: Hydrogels for 3D Neural Tissue Models: Understanding Cell-Material Interactions at a Molecular Level
Hydrogels for 3D Neural Tissue Models: Understanding Cell-Material Interactions at a Molecular Level Open
The development of 3D neural tissue analogs is of great interest to a range of biomedical engineering applications including tissue engineering of neural interfaces, treatment of neurodegenerative diseases and in vitro assessment of…
View article: Stretchable bioelectronics: Mitigating the challenges of the percolation threshold in conductive elastomers
Stretchable bioelectronics: Mitigating the challenges of the percolation threshold in conductive elastomers Open
Conductive polymer (CP)–elastomer composites have been proposed as an alternative to the metals conventionally used for bioelectronic devices. Being softer and more stretchable than metals such as platinum and gold, they can mitigate the a…
View article: Actively controlled local drug delivery using conductive polymer-based devices
Actively controlled local drug delivery using conductive polymer-based devices Open
Localized and actively controlled delivery of drugs presents an opportunity for improving bioavailability, therapeutic efficacy, and long-term treatment of injury or disease. Conductive polymer (CP) based systems present a unique opportuni…
View article: Mechanically Robust Soft Bioelectronics: Towards Conductive Elastomers with a Low Percolation Threshold
Mechanically Robust Soft Bioelectronics: Towards Conductive Elastomers with a Low Percolation Threshold Open
View article: Conductive elastomer composites for fully polymeric, flexible bioelectronics
Conductive elastomer composites for fully polymeric, flexible bioelectronics Open
Soft, flexible and stretchable conductive elastomers made of polyurethane and PEDOT:PSS blends were fabricated into fully polymeric implantable bioelectrode arrays.
View article: Stimulation of peripheral nerves using conductive hydrogel electrodes
Stimulation of peripheral nerves using conductive hydrogel electrodes Open
Nerve block via electrical stimulation of nerves requires a device capable of transferring large amounts of charge across the neural interface on chronic time scales. Current metal electrode designs are limited in their ability to safely a…
View article: Conductive Hydrogel Electrodes for Delivery of Long-Term High Frequency Pulses
Conductive Hydrogel Electrodes for Delivery of Long-Term High Frequency Pulses Open
Nerve block waveforms require the passage of large amounts of electrical energy at the neural interface for extended periods of time. It is desirable that such waveforms be applied chronically, consistent with the treatment of protracted i…
View article: Visual Prosthesis: Interfacing Stimulating Electrodes with Retinal Neurons to Restore Vision
Visual Prosthesis: Interfacing Stimulating Electrodes with Retinal Neurons to Restore Vision Open
The bypassing of degenerated photoreceptors using retinal neurostimulators is helping the blind to recover functional vision. Researchers are investigating new ways to improve visual percepts elicited by these means as the vision produced …
View article: A living electrode construct for incorporation of cells into bionic devices
A living electrode construct for incorporation of cells into bionic devices Open