Joseph Campain
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View article: Characterization and Application of Novel Exercise Recovery Patterns That Reflect Cardiac Performance: A Substudy of the SEQUOIA-HCM Trial
Characterization and Application of Novel Exercise Recovery Patterns That Reflect Cardiac Performance: A Substudy of the SEQUOIA-HCM Trial Open
BACKGROUND: Post-exercise oxygen uptake recovery (VO 2 Rec) is slow in advanced heart failure. We sought to establish easily derived VO 2 Rec measures and evaluate their cardiospecificity and prognostic relevance in patients with dyspnea o…
View article: Impairment of Cardiovascular Functional Capacity in Mild-to-Moderate Kidney Dysfunction
Impairment of Cardiovascular Functional Capacity in Mild-to-Moderate Kidney Dysfunction Open
Key Points Mild-to-moderate CKD is associated with impairment in cardiovascular functional capacity as assessed by oxygen uptake at peak exercise (VO 2 Peak). Cardiac output is significantly reduced in patients with mild-to-moderate CKD an…
View article: Characterization and Prognostic Implications of Respirophasic Variation in Invasive Hemodynamic Measurements at Rest and With Exercise
Characterization and Prognostic Implications of Respirophasic Variation in Invasive Hemodynamic Measurements at Rest and With Exercise Open
Pulmonary capillary wedge pressure (PCWP) is a key measure of left heart congestion used to establish or rule out the diagnosis of heart failure (HF). Diagnostic algorithms for HF with preserved ejection fraction (HFpEF) include or are val…
View article: Systemic Arterial Oxygen Levels Differentiate Pre- and Post-capillary Predominant Hemodynamic Abnormalities During Exercise in Undifferentiated Dyspnea on Exertion
Systemic Arterial Oxygen Levels Differentiate Pre- and Post-capillary Predominant Hemodynamic Abnormalities During Exercise in Undifferentiated Dyspnea on Exertion Open
BackgroundWhether systemic oxygen levels (SaO2) during exercise can provide a window into invasively derived exercise hemodynamic profiles in patients with undifferentiated dyspnea on exertion is unknown.MethodsWe performed cardiopulmonary…