Joseph E. Arrowsmith
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View article: Factors associated with symptom-to-surgery time in patients undergoing surgical repair for acute type A aortic dissection: an exploratory analysis from a prospective cohort study
Factors associated with symptom-to-surgery time in patients undergoing surgical repair for acute type A aortic dissection: an exploratory analysis from a prospective cohort study Open
Objectives The primary objective of this study was to investigate perioperative factors associated with symptom-to-surgery (STS) time in patients diagnosed with hyper-acute aortic dissection (AAD). The secondary objective was to develop a …
View article: Time critical diagnoses and transfers of patients with acute type A aortic dissection in the <scp>UK</scp> : national audit of current practice*
Time critical diagnoses and transfers of patients with acute type A aortic dissection in the <span>UK</span> : national audit of current practice* Open
Summary Background Type A aortic dissection repair is one of the most common emergency cardiac surgical procedures undertaken in the UK and has a high mortality. Early diagnosis and prompt surgery by an expert cardiac surgical team is cruc…
View article: Management of acute aortic dissection in critical care
Management of acute aortic dissection in critical care Open
Aortic dissections are associated with significant mortality and morbidity, with rapid treatment paramount. They are caused by a tear in the intimal lining of the aorta that extends into the media of the wall. Blood flow through this tear …
View article: Optimal protamine dosing after cardiopulmonary bypass: The PRODOSE adaptive randomised controlled trial
Optimal protamine dosing after cardiopulmonary bypass: The PRODOSE adaptive randomised controlled trial Open
Background The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical models of heparin clearance is postulate…