Joseph M. Gullett
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View article: Model-Based Person Fit Statistics Applied to the Wechsler Adult Intelligence Scale IV
Model-Based Person Fit Statistics Applied to the Wechsler Adult Intelligence Scale IV Open
An important task in clinical neuropsychology is to evaluate whether scores obtained on a test battery, such as the Wechsler Adult Intelligence Scale Fourth Edition (WAIS-IV), can be considered “credible” or “valid” for a particular patien…
View article: Your Brain Doesn’t Look a Day Past 70! Cross-Sectional Associations with Brain-Predicted Age in the Cognitively-Intact Oldest-Old
Your Brain Doesn’t Look a Day Past 70! Cross-Sectional Associations with Brain-Predicted Age in the Cognitively-Intact Oldest-Old Open
The cognitively-intact oldest-old (85+) may be the most-resilient members of their birth cohort; due to survivorship effects (e.g., depletion of susceptibles), risk factors associated with brain aging biomarkers in younger samples may not …
View article: Deep Learning with Imbalanced Data Identifies Early Mild Cognitive Impairment Amongst Typical Older Adults (Preprint)
Deep Learning with Imbalanced Data Identifies Early Mild Cognitive Impairment Amongst Typical Older Adults (Preprint) Open
BACKGROUND Mild cognitive impairment is a transitional stage between normal cognitive aging and dementia. Identifying individuals at the preMCI stage, prior to the onset of mild cognitive decline, can be pivotal for early interventions ai…
View article: Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial
Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial Open
Background Both alcohol consumption and HIV infection are associated with worse brain, cognitive, and clinical outcomes in older adults. However, the extent to which brain and cognitive dysfunction is reversible with reduction or cessation…
View article: 3 Associations Between Exercise Type, Fluid Intelligence, and Processing Speed in the Oldest-Old
3 Associations Between Exercise Type, Fluid Intelligence, and Processing Speed in the Oldest-Old Open
Objective: Exercise elicits a variety of physiological responses in the body. In the brain, exercise can modulate levels of neurotransmitters and other neurochemicals as well as sparking neurogenesis and structural changes. Downstream psyc…
View article: Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial (Preprint)
Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial (Preprint) Open
BACKGROUND Both alcohol consumption and HIV infection are associated with worse brain, cognitive, and clinical outcomes in older adults. However, the extent to which brain and cognitive dysfunction is reversible with reduction or cessatio…
View article: Presurgical microstructural coherence predicts cognitive change for bariatric surgery patients
Presurgical microstructural coherence predicts cognitive change for bariatric surgery patients Open
Objective This observational study examined the relationship between presurgical white matter microstructural coherence and cognitive change after weight loss. It was hypothesized that higher baseline fractional anisotropy (FA) would predi…
View article: Associations between physical exercise type, fluid intelligence, executive function, and processing speed in the oldest-old (85 +)
Associations between physical exercise type, fluid intelligence, executive function, and processing speed in the oldest-old (85 +) Open
View article: Computerized adaptive test strategies for the matrix reasoning subtest of the Wechsler Adult Intelligence Scale, 4th Edition (WAIS-IV)
Computerized adaptive test strategies for the matrix reasoning subtest of the Wechsler Adult Intelligence Scale, 4th Edition (WAIS-IV) Open
Objective: Most neuropsychological tests were developed without the benefit of modern psychometric theory. We used item response theory (IRT) methods to determine whether a widely used test – the 26-item Matrix Reasoning subtest of the WAI…
View article: Resting state connectivity in people living with HIV before and after stopping heavy drinking
Resting state connectivity in people living with HIV before and after stopping heavy drinking Open
Background Heavy alcohol use in people living with HIV (PLWH) has widespread negative effects on neural functioning. It remains unclear whether experimentally-induced reduction in alcohol use could reverse these effects. We sought to deter…
View article: Using alcohol biosensors and biomarkers to measure changes in drinking: Associations between transdermal alcohol concentration, phosphatidylethanol, and self-report in a contingency management study of persons with and without HIV.
Using alcohol biosensors and biomarkers to measure changes in drinking: Associations between transdermal alcohol concentration, phosphatidylethanol, and self-report in a contingency management study of persons with and without HIV. Open
Alcohol use can be measured in many ways, including objectively through transdermal alcohol biosensors (e.g., transdermal alcohol concentration; TAC) or blood biomarkers (e.g., phosphatidylethanol; PEth), or subjectively through self-repor…
View article: Resting-state network functional connectivity before and after bariatric surgery
Resting-state network functional connectivity before and after bariatric surgery Open
View article: Baseline Neuroimaging Predicts Decline to Dementia From Amnestic Mild Cognitive Impairment
Baseline Neuroimaging Predicts Decline to Dementia From Amnestic Mild Cognitive Impairment Open
Background and Objectives: Prediction of decline to dementia using objective biomarkers in high-risk patients with amnestic mild cognitive impairment (aMCI) has immense utility. Our objective was to use multimodal MRI to (1) determine whet…
View article: Associations of alcohol use, HIV infection, and age with brain white matter microstructure
Associations of alcohol use, HIV infection, and age with brain white matter microstructure Open
View article: Reduced Working Memory is Associated with Heavier Alcohol Consumption History, Role Impairment and Executive Function Difficulties
Reduced Working Memory is Associated with Heavier Alcohol Consumption History, Role Impairment and Executive Function Difficulties Open
View article: MicroRNA predicts cognitive performance in healthy older adults
MicroRNA predicts cognitive performance in healthy older adults Open
View article: The association of white matter free water with cognition in older adults
The association of white matter free water with cognition in older adults Open
View article: History of Alcohol Consumption and HIV Status Related to Functional Connectivity Differences in the Brain During Working Memory Performance
History of Alcohol Consumption and HIV Status Related to Functional Connectivity Differences in the Brain During Working Memory Performance Open
Background: Poorer working memory function has previously been associated with alcohol misuse, Human Immunodeficiency Virus (HIV) positive status, and risky behavior. Poorer working memory performance relates to alterations in specific bra…
View article: The joint effect of aging and HIV infection on microstructure of white matter bundles
The joint effect of aging and HIV infection on microstructure of white matter bundles Open
Recent evidence suggests the aging process is accelerated by HIV. Degradation of white matter (WM) has been independently associated with HIV and healthy aging. Thus, WM may be vulnerable to joint effects of HIV and aging. Diffusion‐weight…
View article: Cytokine-associated fatigue prior to, during, and post-chemotherapy for breast cancer
Cytokine-associated fatigue prior to, during, and post-chemotherapy for breast cancer Open
View article: Relationship of fatigue with cognitive performance in women with early‐stage breast cancer over 2 years
Relationship of fatigue with cognitive performance in women with early‐stage breast cancer over 2 years Open
Objective Fatigue and cognitive dysfunction are major concerns for women with early‐stage breast cancer during treatment and into survivorship. However, interrelationships of these phenomena and their temporal patterns over time are not we…
View article: Temporal lobe epilepsy affects spatial organization of entorhinal cortex connectivity
Temporal lobe epilepsy affects spatial organization of entorhinal cortex connectivity Open
View article: Neural response to working memory demand predicts neurocognitive deficits in HIV
Neural response to working memory demand predicts neurocognitive deficits in HIV Open
View article: Test-retest reliability of high angular resolution diffusion imaging acquisition within medial temporal lobe connections assessed via tract based spatial statistics, probabilistic tractography and a novel graph theory metric
Test-retest reliability of high angular resolution diffusion imaging acquisition within medial temporal lobe connections assessed via tract based spatial statistics, probabilistic tractography and a novel graph theory metric Open