Suzanne J. Baker
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View article: “I could be living a totally different life right now”: lived experience and caregiver perspectives on the prevention of eating disorders
“I could be living a totally different life right now”: lived experience and caregiver perspectives on the prevention of eating disorders Open
View article: STRprofiler: efficient comparisons of short tandem repeat profiles for biomedical model authentication
STRprofiler: efficient comparisons of short tandem repeat profiles for biomedical model authentication Open
Summary Short tandem repeat (STR) profiling is commonly performed for authentication of biomedical models of human origin, yet no tools exist to easily compare sets of STR profiles to each other or an existing database in a high-throughput…
View article: IMMU-03. DELETION OF RASA2 IN CAR T CELLS OVERCOMES DYSFUNCTIONAL IMMUNE SYNAPSE FORMATION AGAINST DIPGS, ENHANCING IN VITRO AND IN VIVO ANTITUMOR RESPONSE
IMMU-03. DELETION OF RASA2 IN CAR T CELLS OVERCOMES DYSFUNCTIONAL IMMUNE SYNAPSE FORMATION AGAINST DIPGS, ENHANCING IN VITRO AND IN VIVO ANTITUMOR RESPONSE Open
BACKGROUND Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal pediatric brain tumors and a leading cause of cancer-related death in children. There is currently no cure for DIPG, highlighting an urgent need for novel therapeutics.…
View article: MDB-13. GERMLINE<i>ELP1</i> DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA
MDB-13. GERMLINE<i>ELP1</i> DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA Open
BACKGROUND Germline loss-of-function (LOF) variants in Elongator complex protein 1 (ELP1) are the most prevalent predisposing genetic events observed in medulloblastoma (MB), accounting for 30% of the Sonic Hedgehog 3 subtype (SHH-3). Mole…
View article: From awareness to action: an urgent call to reduce mortality and improve outcomes in eating disorders
From awareness to action: an urgent call to reduce mortality and improve outcomes in eating disorders Open
Summary High mortality rates and poor outcomes from eating disorders, especially anorexia nervosa, are largely preventable and require urgent action. A national strategy to address this should include prevention; early detection; timely ac…
View article: Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations
Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations Open
View article: Correlation between Multiparametric MR Imaging and Molecular Genetics in Pontine Pediatric High-Grade Glioma
Correlation between Multiparametric MR Imaging and Molecular Genetics in Pontine Pediatric High-Grade Glioma Open
ADC histogram parameters are correlated with histone H3 mutation status in pontine pediatric high-grade glioma.
View article: DIPG-20. DELINEATING MEDIATORS OF ONCOGENESIS IN FOXR2-EXPRESSING DIFFUSE MIDLINE GLIOMAS
DIPG-20. DELINEATING MEDIATORS OF ONCOGENESIS IN FOXR2-EXPRESSING DIFFUSE MIDLINE GLIOMAS Open
BACKGROUND Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating event, they are insufficient to drive gliomagenesis. Histone mutations co-occur with somati…
View article: Oncohistones and disrupted development in pediatric-type diffuse high-grade glioma
Oncohistones and disrupted development in pediatric-type diffuse high-grade glioma Open
View article: Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Effective data sharing is key to accelerating research to improve diagnostic precision, treatment efficacy, and long-term survival in pediatric cancer and other childhood catastrophic diseases. We present St. Jude Cloud (https://www.stjude…
View article: Supplementary Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Supplementary Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Involves Supplementary Table Legends and Supplementary Figures and associated legends
View article: Supplementary Tables from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Supplementary Tables from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Excel file of Supplementary Tables
View article: Supplementary Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Supplementary Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Involves Supplementary Table Legends and Supplementary Figures and associated legends
View article: Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Effective data sharing is key to accelerating research to improve diagnostic precision, treatment efficacy, and long-term survival in pediatric cancer and other childhood catastrophic diseases. We present St. Jude Cloud (https://www.stjude…
View article: Supplementary Tables from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem
Supplementary Tables from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem Open
Excel file of Supplementary Tables
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 52K
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 52K
View article: Supplementary Figure S4 from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation
Supplementary Figure S4 from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation Open
Early perivascular medulloblastoma tumor cells are Pten null
View article: Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 86K
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Table 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 49K
View article: Data from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Data from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across…
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
View article: Supplementary Figure Legends from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation
Supplementary Figure Legends from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation Open
Supplementary Figure legends
View article: Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits Open
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits