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Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts Open

Zer Vue, Peter T. Ajayi, Kit Neikirk, Alexandria C. Murphy, Praveena Prasad , et al. · 2023

This study, utilizing SBF-SEM, reveals structural alterations in mitochondria and myofibrils in human heart failure (HF). Mitochondria in HF show changes in structure, while myofibrils exhibit increased cross-sectional area and branching. …