Josh Rowe
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View article: Mass Balance and Metabolism of <scp> <sup>14</sup> C </scp> ‐Atogepant in Healthy Male Participants: Findings of a Phase 1 Clinical Trial
Mass Balance and Metabolism of <span> <sup>14</sup> C </span> ‐Atogepant in Healthy Male Participants: Findings of a Phase 1 Clinical Trial Open
Atogepant, a calcitonin gene‐related peptide (CGRP) receptor antagonist, is approved for the preventive treatment of migraine in adults. This open‐label, phase 1 study examined radiolabeled atogepant ( 14 C‐atogepant) metabolism, eliminati…
View article: Mechanistic Investigations Support Liver Safety of Ubrogepant
Mechanistic Investigations Support Liver Safety of Ubrogepant Open
Small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated therapeutic efficacy for the treatment of migraine. However, previously investigated CGRP receptor antagonists, telcagepant and MK-3207, were disc…
View article: Liver and muscle glycogen oxidation and performance with dose variation of glucose–fructose ingestion during prolonged (3 h) exercise
Liver and muscle glycogen oxidation and performance with dose variation of glucose–fructose ingestion during prolonged (3 h) exercise Open