Joshua A. Bagley
YOU?
Author Swipe
View article: A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids
A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids Open
View article: Hypersensitivity controlled by mir-9a modulates female receptivity of<i>Drosophila melanogaster</i>
Hypersensitivity controlled by mir-9a modulates female receptivity of<i>Drosophila melanogaster</i> Open
Female Drosophila melanogaster undergo a complex behavioral transformation following mating, characterized by increased sensory sensitivity and altered reproductive behaviors. In this study, we investigated the role of miR-9a, a conserved …
View article: Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration
Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration Open
Inhibitory GABAergic interneurons migrate over long distances from their extracortical origin into the developing cortex. In humans, this process is uniquely slow and prolonged, and it is unclear whether guidance cues unique to humans gove…
View article: A human tissue screen identifies a regulator of ER secretion as a brain-size determinant
A human tissue screen identifies a regulator of ER secretion as a brain-size determinant Open
Functional screen for microcephaly genes Genetic screens are widely used to identify regulators in biological processes. Human screens are currently limited to two-dimensional cell cultures, which lack the ability to score tissue-dependent…
View article: Human blood vessel organoids as a model of diabetic vasculopathy
Human blood vessel organoids as a model of diabetic vasculopathy Open
View article: Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects
Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects Open
Significance It remains unclear how the structural properties of polyglutamine (polyQ) proteins, which underlie several neurodegenerative disorders, including Huntington’s disease and spinocerebellar ataxias (SCAs), translate into the toxi…
View article: Author Correction: Genetically engineered cerebral organoids model brain tumor formation
Author Correction: Genetically engineered cerebral organoids model brain tumor formation Open
View article: Genetically engineered cerebral organoids model brain tumor formation
Genetically engineered cerebral organoids model brain tumor formation Open
View article: Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons
Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons Open
View article: Detailed Cerebral Organoid Fusion Method
Detailed Cerebral Organoid Fusion Method Open
View article: Fused dorsal-ventral cerebral organoids model human cortical interneuron migration
Fused dorsal-ventral cerebral organoids model human cortical interneuron migration Open
Development of the forebrain involves the migration of GABAergic interneurons over long distances from ventral into dorsal regions. Although defects in interneuron migration are implicated in neuropsychiatric diseases such as Epilepsy, Aut…