Joshua A. Hackney
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View article: Prevention of tuberculosis in macaques after intravenous BCG immunization
Prevention of tuberculosis in macaques after intravenous BCG immunization Open
Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide 1 . The only available vaccine, BCG (Bacillus Calmette–Guérin), is given intradermally and has variable efficacy against pulmonary tuberculosis, the ma…
View article: Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates
Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates Open
Invariant NKT (iNKT) cells in both humans and non-human primates are activated by the glycolipid antigen, α-galactosylceramide (α-GalCer). However, the extent to which the molecular mechanisms of antigen recognition and in vivo phenotypes …