Joshua Brown-Clay
2023
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus
2023 • Takouhie Mgrditchian, Joshua Brown-Clay, Céline Hoffmann, Tanja Müller, Liza Filali, Elena Ockfen, Xianqing Mao, Flora Moreau, Carla Pou Casellas,...
Exploring foci of
2023-05-15
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus
2023-05-15 • Takouhie Mgrditchian, Joshua Brown-Clay, Céline Hoffmann, Tanja Müller, Liza Filali, Elena Ockfen, Xianqing Mao, Flora Moreau, Carla Pou Casellas,...
The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin dynamics in the cytoplasm control the formation of invadopodia, which are membrane protrusions that facilitate cancer cell invasion by focusing the secretion of extracellular matrix-degrading enzymes, including matrix metalloproteinases (MMPs). In this study, we investigated the nuclear role of cysteine-rich protein 2 (CRP2), a two LIM domain-containing F-a…
Beta-Actin
Actin
Cytoskeleton
Exploring foci of
2023-03-31
Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
2023-03-31 • Antoun Al Absi, Hannah Wurzer, Coralie L. Guérin, Céline Hoffmann, Flora Moreau, Xianqing Mao, Joshua Brown-Clay, Rémi Petrolli, Carla Pou Casellas...
<p>Supplementary Figures S1-S6 and their legends</p>
Portrait Of An Artist (Pool With Two Figures)
Force 10 From Navarone (Film)
Fire From The Gods
List Of Philippine Mythological Figures
The Cat From Outer Space
From Elvis In Memphis
Something From Tiffany's
Argument From Ignorance
2020–2021 U.S. Troop Withdrawal From Afghanistan
Exploring foci of
2023-03-31
Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
2023-03-31 • Antoun Al Absi, Hannah Wurzer, Coralie L. Guérin, Céline Hoffmann, Flora Moreau, Xianqing Mao, Joshua Brown-Clay, Rémi Petrolli, Carla Pou Casellas...
<div>Abstract<p>Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskeleton in breast cancer cell resistance to cytotoxic natural killer (NK) cells. A significant fraction of breast cancer cells responded to NK-cell attack via a surprisingly rapid and massive accumulation of F-actin near the immunologic synapse, a process…
Notes From The Internet Apocalypse
The Girl From The Well
Fire From Heaven
Letters From Yelena
Fierce Invalids Home From Hot Climates
Freed From Desire
List Of Fatalities From Aviation Accidents
Gift From The Sea
Live From Daryl's House
Exploring foci of
2023-03-31
Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
2023-03-31 • Antoun Al Absi, Hannah Wurzer, Coralie L. Guérin, Céline Hoffmann, Flora Moreau, Xianqing Mao, Joshua Brown-Clay, Rémi Petrolli, Carla Pou Casellas...
<div>Abstract<p>Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskeleton in breast cancer cell resistance to cytotoxic natural killer (NK) cells. A significant fraction of breast cancer cells responded to NK-cell attack via a surprisingly rapid and massive accumulation of F-actin near the immunologic synapse, a process…
The Judge From Hell
Miracles From Heaven (Book)
Escape From Freedom
From Zero World Tour
Girl From Nowhere
The Man From St. Petersburg
Emigration From The Eastern Bloc
Do Not Expect Too Much From The End Of The World
Voices From Chernobyl
Exploring foci of
2023-03-31
Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
2023-03-31 • Antoun Al Absi, Hannah Wurzer, Coralie L. Guérin, Céline Hoffmann, Flora Moreau, Xianqing Mao, Joshua Brown-Clay, Rémi Petrolli, Carla Pou Casellas...
<p>Supplementary Figures S1-S6 and their legends</p>
Removal Of Cannabis From Schedule I Of The Controlled Substances Act
Health Effects Arising From The September 11 Attacks
Escape From Alcatraz (Film)
Death From Above 1979
Men Are From Mars, Women Are From Venus
Far From The Madding Crowd
The Boys From Brazil (Film)
Songs From The Big Chair
From Russia With Love (Film)