Joshua Charkow
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View article: mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format
mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format Open
Advances in mass spectrometry (MS) instrumentation, including higher resolution, faster scan speeds, and improved sensitivity, have dramatically increased the data volume and complexity. The adoption of imaging and ion mobility further amp…
View article: OpenMS WebApps: Building User-Friendly Solutions for MS Analysis
OpenMS WebApps: Building User-Friendly Solutions for MS Analysis Open
Liquid chromatography-mass spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be …
View article: OpenMS WebApps: Building User-Friendly Solutions for MS Analysis
OpenMS WebApps: Building User-Friendly Solutions for MS Analysis Open
Liquid Chromatography Mass Spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be …
View article: pyOpenMS-viz: Streamlining Mass Spectrometry Data Visualization with pandas
pyOpenMS-viz: Streamlining Mass Spectrometry Data Visualization with pandas Open
Mass spectrometry data visualization is essential for a wide range of applications, such as validation of workflows and results, benchmarking new algorithms, and creating comprehensive quality control reports. Python offers a popular and p…
View article: MassDash: A Web-based Dashboard for Data-Independent Acquisition Mass Spectrometry Visualization
MassDash: A Web-based Dashboard for Data-Independent Acquisition Mass Spectrometry Visualization Open
With the increased usage, diversity of methods and instruments being applied to analyze Data-Independent Acquisition (DIA) data, visualization is becoming increasingly important to validate automated software results. Here we present MassD…
View article: OpenMS 3 expands the frontiers of open-source computational mass spectrometry
OpenMS 3 expands the frontiers of open-source computational mass spectrometry Open
Mass spectrometry has become an indispensable tool in the life sciences. The new major version 3 of the computational framework OpenMS provides significant advancements regarding open, scalable, and reproducible high-throughput workflows f…
View article: Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature
Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature Open
View article: Trapped Ion Mobility Spectrometry Reduces Spectral Complexity in Mass Spectrometry Based Workflow
Trapped Ion Mobility Spectrometry Reduces Spectral Complexity in Mass Spectrometry Based Workflow Open
In bottom-up mass spectrometry based proteomics, deep proteome coverage is limited by high cofragmentation rates. This occurs when more than one analyte is isolated by the quadrupole and the subsequent fragmentation event produces fragment…