Joshua D. Lee
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View article: Factors contributing to the expansion of medication for opioid use disorder (MOUD) within the New Hampshire Department of Corrections (NHDOC)
Factors contributing to the expansion of medication for opioid use disorder (MOUD) within the New Hampshire Department of Corrections (NHDOC) Open
Policy-related, organizational, and individual factors contributed to the expansion of the MOUD program at the NHDOC. EXIT-CJS recruitment occurred synergistically with the expansion of the MOUD program. As NHDOC was engaged as a site in E…
View article: Comparative effectiveness of extended‐release naltrexone versus buprenorphine‐naloxone on treatment interruption: Comparing findings from a reanalysis of the X:BOT RCT and harmonized target trial emulation using population‐based observational data
Comparative effectiveness of extended‐release naltrexone versus buprenorphine‐naloxone on treatment interruption: Comparing findings from a reanalysis of the X:BOT RCT and harmonized target trial emulation using population‐based observational data Open
Background and aims It is unclear if findings from randomized controlled trials (RCT) of medications for opioid use disorder apply to real‐world settings. We estimated the effectiveness of buprenorphine‐naloxone (BUP‐NX) versus extended‐re…
View article: W3ID: A Quantum Computing-Secure Digital Identity System Redefining Standards for Web3 and Digital Twins
W3ID: A Quantum Computing-Secure Digital Identity System Redefining Standards for Web3 and Digital Twins Open
The rapid advancements in quantum computing present significant threats to existing encryption standards and internet security. Simultaneously, the advent of Web 3.0 marks a transformative era in internet history, emphasizing enhanced data…
View article: Injectable Buprenorphine During Transition Out of Prison: A Pilot Partially Randomized Preference Trial Protocol
Injectable Buprenorphine During Transition Out of Prison: A Pilot Partially Randomized Preference Trial Protocol Open
View article: “I Can Combine Those Things to be a Superhero” a Qualitative Study of the Motivations for High-Risk Polysubstance Use
“I Can Combine Those Things to be a Superhero” a Qualitative Study of the Motivations for High-Risk Polysubstance Use Open
The current study aimed to understand motivations of high-risk polysubstance use. Semi-structured interviews were conducted in New York City with 20 individuals with frequent recent polysubstance use. Two analysts coded the interviews (κ =…
View article: Localized Evaporative Cooling Explains Observed Ocular Surface-Temperature Patterns
Localized Evaporative Cooling Explains Observed Ocular Surface-Temperature Patterns Open
Significant differences in corneal temperature-decline rate and evaporation rate between LCR and LWR were quantified using infrared thermography. In agreement with literature, LCRs and LWRs correlate directly with fluorescein break-up area…
View article: Assessing the impact of jail-initiated medication for opioid use disorder: A multisite analysis of the SOMATICS collaborative
Assessing the impact of jail-initiated medication for opioid use disorder: A multisite analysis of the SOMATICS collaborative Open
The objective of this study was to estimate the associations of jail-initiated medication for opioid use disorder (MOUD) and patient navigation (PN) with opioid use disorder (OUD) at 6 months post-release. Three randomized trials (combined…
View article: Fentanyl Test Strips for Harm Reduction: A Scoping Review
Fentanyl Test Strips for Harm Reduction: A Scoping Review Open
Background High potency synthetic opioids like fentanyl have continued to replace or contaminate the supply of illicit drugs in North America, with fentanyl test strips (FTSs) often used as a harm reduction tool for overdose prevention. Th…
View article: Impact of jail-based methadone or buprenorphine treatment on non-fatal opioid overdose after incarceration
Impact of jail-based methadone or buprenorphine treatment on non-fatal opioid overdose after incarceration Open
View article: Target trial emulation for comparative effectiveness research with observational data: Promise and challenges for studying medications for opioid use disorder
Target trial emulation for comparative effectiveness research with observational data: Promise and challenges for studying medications for opioid use disorder Open
Medications for opioid use disorder (MOUD) increase retention in care and decrease mortality during active treatment; however, information about the comparative effectiveness of different forms of MOUD is sparse. Observational comparative …
View article: Research on the bidirectional relationships between sleep and parkinsons disease
Research on the bidirectional relationships between sleep and parkinsons disease Open
Parkinsons disease (PD) is the second most prevalent neurodegenerative disease in the world, and among its most common symptoms is sleep disruption. Due to the glymphatic systems role in removing alpha-synuclein and other substances relate…
View article: Jail-based medication for opioid use disorder and patterns of reincarceration and acute care use after release: A sequence analysis
Jail-based medication for opioid use disorder and patterns of reincarceration and acute care use after release: A sequence analysis Open
View article: Transitions of care between jail-based medications for opioid use disorder and ongoing treatment in the community: A retrospective cohort study
Transitions of care between jail-based medications for opioid use disorder and ongoing treatment in the community: A retrospective cohort study Open
Background and Aims Offering medications for opioid use disorder (MOUD) in carceral settings can significantly reduce overdose risk. However, it is unknown whether and to what extent individuals in U.S. jail settings continue MOUD once the…
View article: Department of Error
Department of Error Open
View article: Secondary Analysis of Agreement Between Negative Timeline Follow Back Report and Negative Urine Toxicology in a Large Trial of Individuals with Opioid Use Disorder
Secondary Analysis of Agreement Between Negative Timeline Follow Back Report and Negative Urine Toxicology in a Large Trial of Individuals with Opioid Use Disorder Open
Objectives Timeline follow-back (TLFB) is a self-report measure commonly used as a method of assessing historical drug use in both clinical and research settings. Our study considered rates of agreement between TLFB and an objective biolog…
View article: Integrating Text Messaging in a Low Threshold Telebuprenorphine Program for New York City Residents with Opioid Use Disorder during COVID-19: A Pilot Randomized Controlled Trial
Integrating Text Messaging in a Low Threshold Telebuprenorphine Program for New York City Residents with Opioid Use Disorder during COVID-19: A Pilot Randomized Controlled Trial Open
Background Pragmatic innovations are needed to optimize clinical outcomes among people who use opioids initiating buprenorphine. This pilot randomized controlled trial assessed the feasibility of integrating text messaging in a low thresho…
View article: Patient Perceptions of Integrating Meditation-based Interventions in Office-based Opioid Treatment with Buprenorphine: A Mixed-methods Survey
Patient Perceptions of Integrating Meditation-based Interventions in Office-based Opioid Treatment with Buprenorphine: A Mixed-methods Survey Open
Introduction Recent findings support the provision of meditation-based interventions (MBIs) in primary care. However, the acceptability of MBI among patients prescribed medications for opioid use disorder (eg, buprenorphine) in primary car…
View article: Trajectories of depression among patients in treatment for opioid use disorder: A growth mixture model secondary analysis of the XBOT trial
Trajectories of depression among patients in treatment for opioid use disorder: A growth mixture model secondary analysis of the XBOT trial Open
Background and Objectives To inform clinical practice, we identified subgroups of adults based on levels of depression symptomatology over time during opioid use disorder (OUD) treatment. Methods Participants were 474 adults in a 24‐week t…
View article: Provider and administrator attitudes and experiences with implementing telebuprenorphine during the COVID-19 pandemic: a mixed-methods survey
Provider and administrator attitudes and experiences with implementing telebuprenorphine during the COVID-19 pandemic: a mixed-methods survey Open
Findings from this study highlight considerable heterogeneity in the delivery of telebuprenorphine services.
View article: The impact of COVID-19 on the treatment of opioid use disorder in carceral facilities: a cross-sectional study
The impact of COVID-19 on the treatment of opioid use disorder in carceral facilities: a cross-sectional study Open
While the COVID-19 pandemic disrupted healthcare delivery everywhere, persons with carceral system involvement and opioid use disorder (OUD) were disproportionately impacted and vulnerable to severe COVID-associated illness. Carceral setti…
View article: Association between jail‐based methadone or buprenorphine treatment for opioid use disorder and overdose mortality after release from New York City jails 2011–17
Association between jail‐based methadone or buprenorphine treatment for opioid use disorder and overdose mortality after release from New York City jails 2011–17 Open
Background and aims Opioid overdose is a leading cause of death during the immediate time after release from jail or prison. Most jails in the United States do not provide methadone and buprenorphine treatment for opioid use disorder (MOUD…
View article: Injecting Opioid Use Disorder Treatment in Jails and Prisons: The Potential of Extended-release Buprenorphine in the Carceral Setting.
Injecting Opioid Use Disorder Treatment in Jails and Prisons: The Potential of Extended-release Buprenorphine in the Carceral Setting. Open
As the opioid overdose cases rise, policy-makers and researchers should target interventions to populations at highest risk. Incarceration serves as a risk factor for opioid overdose (Gan et al. Addiction 2021) and a large portion of recen…
View article: Polysubstance use before and during treatment with medication for opioid use disorder: Prevalence and association with treatment outcomes
Polysubstance use before and during treatment with medication for opioid use disorder: Prevalence and association with treatment outcomes Open
View article: Methamphetamine/amphetamine use over time among persons with opioid use disorders treated with buprenorphine/naloxone versus extended-release naltrexone
Methamphetamine/amphetamine use over time among persons with opioid use disorders treated with buprenorphine/naloxone versus extended-release naltrexone Open
View article: Perceptions and experiences toward extended-release buprenorphine among persons leaving jail with opioid use disorders before and during COVID-19: an in-depth qualitative study
Perceptions and experiences toward extended-release buprenorphine among persons leaving jail with opioid use disorders before and during COVID-19: an in-depth qualitative study Open
View article: Airborne Isolation Cardiac Arrest: A Simulation Program for Interdisciplinary Code Blue Team Training
Airborne Isolation Cardiac Arrest: A Simulation Program for Interdisciplinary Code Blue Team Training Open
Our simulation program allowed a small number of educators to feasibly train a large number of learners, let learners practice required skills, and improved learners' self-assessed knowledge, skills, and confidence regarding quality and sa…
View article: A Toolkit for Circular Construction of Retail and Commercial Spaces
A Toolkit for Circular Construction of Retail and Commercial Spaces Open
Retail interior fit-outs have an average lifespan of only 4.5 years¹ while commercial fit-outs average just 7.8 years.² This extremely rapid turnover is significantly shorter than other project typologies and contributes an outsized portio…
View article: A Mixed-Methods Evaluation of the Feasibility of a Medical Management-Based Text Messaging Intervention Combined With Buprenorphine in Primary Care
A Mixed-Methods Evaluation of the Feasibility of a Medical Management-Based Text Messaging Intervention Combined With Buprenorphine in Primary Care Open
Background: Mobile health (mHealth) tools offer an effective and personalized approach to enhance chronic disease management and may partially offset provider-level barriers to increasing buprenorphine prescribing in primary care. This stu…
View article: Commentary on Ajazi et al (2021) Re-analysis of the X:BOT Trial
Commentary on Ajazi et al (2021) Re-analysis of the X:BOT Trial Open
Lee, Joshua D. MD, MSc; Nunes, Edward V. MD; Novo, Patricia MPA, MPH; May, Jeanine PhD; Matthews, Abigail PhD; Van Veldhuisen, Paul PhD; Lindblad, Robert MD; Liu, David MD; Rotrosen, John MD Author Information
View article: Comparison of Treatment Retention of Adults With Opioid Addiction Managed With Extended-Release Buprenorphine vs Daily Sublingual Buprenorphine-Naloxone at Time of Release From Jail
Comparison of Treatment Retention of Adults With Opioid Addiction Managed With Extended-Release Buprenorphine vs Daily Sublingual Buprenorphine-Naloxone at Time of Release From Jail Open
ClinicalTrials.gov Identifier: NCT03604159.