Joshua Karpf
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View article: Astrocyte Extracellular Matrix Modulates Neuronal Dendritic Development
Astrocyte Extracellular Matrix Modulates Neuronal Dendritic Development Open
Major developmental events occurring in the hippocampus during the third trimester of human gestation and neonatally in altricial rodents include rapid and synchronized dendritic arborization and astrocyte proliferation and maturation. We …
View article: Characterization of normative fetal rhesus macaque brain development with magnetic resonance imaging
Characterization of normative fetal rhesus macaque brain development with magnetic resonance imaging Open
Advances in motion correction magnetic resonance imaging methods have made it possible to track anatomical changes throughout the highly dynamic phase of fetal neurodevelopment. Characterizing the trajectory of normative brain development …
View article: Gestational and early postnatal protein malnutrition disrupts neurodevelopment in rhesus macaques
Gestational and early postnatal protein malnutrition disrupts neurodevelopment in rhesus macaques Open
Adequate nutrition during gestation is critical for fetal development, and deficits in protein are associated with neurological and behavioral impairments in offspring placing a significant burden on global health. Fetal and neonatal longi…
View article: Brain Charts for the Rhesus Macaque Lifespan
Brain Charts for the Rhesus Macaque Lifespan Open
Recent efforts to chart human brain growth across the lifespan using large-scale MRI data have provided reference standards for human brain development. However, similar models for nonhuman primate (NHP) growth are lacking. The rhesus maca…
View article: Astrocyte extracellular matrix modulates neuronal dendritic development
Astrocyte extracellular matrix modulates neuronal dendritic development Open
Major developmental events occurring in the hippocampus during the third trimester of human gestation and neonatally in altricial rodents include rapid and synchronized dendritic arborization and astrocyte proliferation and maturation. We …
View article: Prenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques
Prenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques Open
Prenatal cannabis use is associated with adverse offspring neurodevelopmental outcomes, however the underlying mechanisms are relatively unknown. We sought to determine the impact of chronic delta-9-tetrahydrocannabinol (THC) exposure on f…
View article: Multi-modal imaging reveals differential brain volumetric, biochemical, and white matter fiber responsivity to repeated intermittent ethanol vapor exposure in male and female rats
Multi-modal imaging reveals differential brain volumetric, biochemical, and white matter fiber responsivity to repeated intermittent ethanol vapor exposure in male and female rats Open
View article: Information processing deficit in older adults with HIV infection: A comparison with Parkinson’s disease.
Information processing deficit in older adults with HIV infection: A comparison with Parkinson’s disease. Open
The notable effects of impaired IP speed, over and above neurotypical age-related declines, indicate that older HIV-infected individuals may have an enhanced vulnerability for developing nonmotor and motor symptoms despite antiretroviral t…