Josiane Bourque
YOU?
Author Swipe
View article: A longitudinal mediation study of peer victimization and resting-state functional connectivity as predictors of development of adolescent psychopathology
A longitudinal mediation study of peer victimization and resting-state functional connectivity as predictors of development of adolescent psychopathology Open
Background Peer victimization (PV) is associated with alterations in neural responses in regions subserving emotional regulatory processes and with increased risk of psychopathology during adolescence. The present study examined the longit…
View article: ModelArray: An R package for statistical analysis of fixel-wise data
ModelArray: An R package for statistical analysis of fixel-wise data Open
Diffusion MRI is the dominant non-invasive imaging method used to characterize white matter organization in health and disease. Increasingly, fiber-specific properties within a voxel are analyzed using fixels. While tools for conducting st…
View article: Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization
Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization Open
Summary We present an empirically benchmarked framework for sex-specific normative modeling of brain morphometry that can inform about the biological and behavioral significance of deviations from typical age-related neuroanatomical change…
View article: ModelArray: a memory-efficient R package for statistical analysis of fixel data
ModelArray: a memory-efficient R package for statistical analysis of fixel data Open
Diffusion MRI is the dominant non-invasive imaging method used to characterize white matter organization in health and disease. Increasingly, fiber-specific properties within a voxel are analyzed using fixels. While tools for conducting st…
View article: Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-based fMRI Meta-analysis
Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-based fMRI Meta-analysis Open
Background Impaired emotion processing constitutes a key dimension of schizophrenia and a possible endophenotype of this illness. Empirical studies consistently report poorer emotion recognition performance in patients with schizophrenia a…
View article: Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages
Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages Open
Mechanisms underpinning neurotypical age-related variations in cortical thickness in the human brain remain insufficiently specified. Here we used cell-specific marker genes, followed by gene ontology and enrichment analyses, to quantify t…
View article: Neural alterations of emotion processing in atypical trajectories of psychotic-like experiences
Neural alterations of emotion processing in atypical trajectories of psychotic-like experiences Open
The aim of this study was to investigate the neural bases of facial emotion processing before the onset of clinical psychotic symptoms in youth belonging to well-defined developmental trajectories of psychotic-like experiences (PLEs). A un…
View article: Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages
Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages Open
Mechanisms underpinning age-related variations in cortical thickness in the human brain remain poorly understood. We investigated whether inter-regional age-related variations in cortical thinning (in a multicohort neuroimaging dataset fro…
View article: Greater male than female variability in regional brain structure across the lifespan
Greater male than female variability in regional brain structure across the lifespan Open
For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta‐Analysis) Consortium presents…
View article: Cannabis and Cognitive Functioning: From Acute to Residual Effects, From Randomized Controlled Trials to Prospective Designs
Cannabis and Cognitive Functioning: From Acute to Residual Effects, From Randomized Controlled Trials to Prospective Designs Open
In recent years, several jurisdictions have revised their regulation policy toward both medical and recreational use of cannabis. These changes have elicited concerns regarding how legalization impacts academic achievement and work perform…
View article: Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years Open
Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association betw…
View article: Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years Open
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may…
View article: Greater male than female variability in regional brain structure across the lifespan
Greater male than female variability in regional brain structure across the lifespan Open
For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta‐Analysis) Consortium presents…
View article: Adolescent Resting-State Brain Networks and Unique Variability of Conduct Problems Within the Externalizing Dimension
Adolescent Resting-State Brain Networks and Unique Variability of Conduct Problems Within the Externalizing Dimension Open
The externalizing psychopathological dimension is associated with alterations in adolescents’ functional brain connectivity. The current study aims to identify the functional correlates of the unique variability in conduct problems within …
View article: QSIPrep: An integrative platform for preprocessing and reconstructing diffusion MRI
QSIPrep: An integrative platform for preprocessing and reconstructing diffusion MRI Open
Diffusion-weighted magnetic resonance imaging (dMRI) has become the primary method for non-invasively studying the organization of white matter in the human brain. While many dMRI acquisition sequences have been developed, they all sample …
View article: Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years
Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years Open
Delineating age-related cortical trajectories in healthy individuals is critical given the association of cortical thickness with cognition and behaviour. Previous research has shown that deriving robust estimates of age-related brain morp…
View article: Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years
Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years Open
Age has a major effect on brain volume. However, the normative studies available are constrained by small sample sizes, restricted age coverage and significant methodological variability. These limitations introduce inconsistencies and may…
View article: Greater male than female variability in regional brain structure across the lifespan
Greater male than female variability in regional brain structure across the lifespan Open
For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents…
View article: Longitudinal Development of Brain Iron Is Linked to Cognition in Youth
Longitudinal Development of Brain Iron Is Linked to Cognition in Youth Open
Brain iron is vital to multiple aspects of brain function, including oxidative metabolism, myelination, and neurotransmitter synthesis. Atypical iron concentration in the basal ganglia is associated with neurodegenerative disorders in agin…
View article: Accelerated Cortical Thinning within Structural Brain Networks is Associated with Irritability in Youth
Accelerated Cortical Thinning within Structural Brain Networks is Associated with Irritability in Youth Open
Background Irritability is an important dimension of psychopathology that spans multiple clinical diagnostic categories, yet its relationship to patterns of brain development remains sparsely explored. Here, we examined how trans-diagnosti…
View article: Developmental neurocognitive pathway of psychosis proneness and the impact of cannabis use
Developmental neurocognitive pathway of psychosis proneness and the impact of cannabis use Open
Cette thèse fait la promotion d’une nouvelle approche ciblant le risque de psychose qui consiste à identifier les enfants et les jeunes adolescents de la communauté appartenant à différentes trajectoires développementales d’expériences psy…
View article: Association of Cannabis Use With Adolescent Psychotic Symptoms
Association of Cannabis Use With Adolescent Psychotic Symptoms Open
This cohort study investigates year-to-year associations between cannabis use and psychosis over 4 years in youth aged 13 to 16 years.