Josip Begovać
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View article: Clinical significance of Epstein-Barr virus DNA quantification in the cerebrospinal fluid
Clinical significance of Epstein-Barr virus DNA quantification in the cerebrospinal fluid Open
Objective: Clinical significance of Epstein-Barr (EBV) virus DNA in the cerebrospinal fluid (CSF) is not fully understood. Our aim was to evaluate clinical implications of detectable EBV DNA in the cerebrospinal fluid (CSF) of immunocompet…
View article: Significant Mortality Reduction from Severe Pneumocystis jirovecii Pneumonia in People Living with HIV and Treated in the Intensive Care Unit, Croatia, 2002–2023
Significant Mortality Reduction from Severe Pneumocystis jirovecii Pneumonia in People Living with HIV and Treated in the Intensive Care Unit, Croatia, 2002–2023 Open
Pneumocystis jirovecii pneumonia (PCP) remains a frequent cause of intensive care unit (ICU) admission among people living with HIV (PLWH), despite widespread antiretroviral therapy (ART) use. We conducted a retrospective cohort study of 3…
View article: Mortality using raltegravir versus other integrase strand-transfer inhibitors in people with HIV in Europe and Australia: a prospective multicentre study
Mortality using raltegravir versus other integrase strand-transfer inhibitors in people with HIV in Europe and Australia: a prospective multicentre study Open
CHU St Pierre Brussels HIV Cohort, Austrian HIV Cohort Study, Australian HIV Observational Database, AIDS Therapy Evaluation in the Netherlands National Observational HIV cohort, EuroSIDA cohort, Frankfurt HIV Cohort Study, Georgian Nation…
View article: Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide Introduced at the First Clinical Visit: A Real-Life Single-Arm Single-center Retrospective Cohort Study
Coformulated Bictegravir, Emtricitabine, and Tenofovir Alafenamide Introduced at the First Clinical Visit: A Real-Life Single-Arm Single-center Retrospective Cohort Study Open
In our real-life clinical setting, same-day treatment with BIC/FTC/TAF was an efficacious and feasible option for achieving viral suppression in treatment-naïve PLWH.
View article: First real-life data on COVID-19 vaccine effectiveness against hospitalisation and severe disease from the eastern part of the WHO European Region
First real-life data on COVID-19 vaccine effectiveness against hospitalisation and severe disease from the eastern part of the WHO European Region Open
View article: Integrase Strand Transfer Inhibitor–Related Changes in Body Mass Index and Risk of Diabetes: A Prospective Study From the RESPOND Cohort Consortium
Integrase Strand Transfer Inhibitor–Related Changes in Body Mass Index and Risk of Diabetes: A Prospective Study From the RESPOND Cohort Consortium Open
Background With integrase strand transfer inhibitor (INSTI) use associated with increased body mass index (BMI) and BMI increases associated with higher diabetes mellitus (DM) risk, we explored the relationships between INSTI/non-INSTI reg…
View article: Mpox across countries from Central and Eastern Europe - 2022 outbreak
Mpox across countries from Central and Eastern Europe - 2022 outbreak Open
Mpox was diagnosed predominantly in young MSM, with high-risk behaviors and history of STIs. Effective contact tracing and vaccination are important strategic pillars to control mpox outbreaks.
View article: Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022
Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022 Open
Molecular epidemiology of HIV-1 infection is challenging due to the highly diverse HIV-genome. We investigated the genetic diversity and prevalence of transmitted drug resistance (TDR) followed by phylogenetic analysis in 270 HIV-1 infecte…
View article: Incidence, risk factors, and clinical findings of syphilis among men living with HIV in Croatia during the COVID-19 pandemic
Incidence, risk factors, and clinical findings of syphilis among men living with HIV in Croatia during the COVID-19 pandemic Open
We conducted a nationwide longitudinal observational study to estimate the incidence of syphilis in a cohort of male persons living with HIV (MLWH) in Croatia in the pre-COVID-19 and COVID-19 years. Data were reviewed and extracted from th…
View article: Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group Open
(1) Background: Viral hepatitis C (HCV) and viral hepatitis B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV and hepatitis A (HAV) and treated for HBV and HCV. We aimed to compare…
View article: Increasing incidence of syphilis among men living with HIV in Croatia during the COVID-19 years 2020 and 2021
Increasing incidence of syphilis among men living with HIV in Croatia during the COVID-19 years 2020 and 2021 Open
We conducted a nationwide longitudinal observational study to estimate the incidence of syphilis in a cohort of male persons living with HIV (PLWH) in Croatia in the pre-COVID-19 and COVID-19 years. Data were reviewed and extracted from th…
View article: PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future
PrEP Scale-Up and PEP in Central and Eastern Europe: Changes in Time and the Challenges We Face with No Expected HIV Vaccine in the near Future Open
With no expected vaccine for HIV in the near future, we aimed to define the current situation and challenges for pre- and post-exposure prophylaxis (PrEP and PEP) in Central and Eastern Europe (CEE). The Euroguidelines CEE Network Group me…
View article: Hepatitis A Outbreak in Men Who Have Sex with Men Using Pre-Exposure Prophylaxis and People Living with HIV in Croatia, January to October 2022
Hepatitis A Outbreak in Men Who Have Sex with Men Using Pre-Exposure Prophylaxis and People Living with HIV in Croatia, January to October 2022 Open
The hepatitis A virus (HAV) is a highly hepatotropic virus transmitted mainly via the fecal–oral route. The purpose of this study is to describe a prolonged HAV outbreak in HIV-infected men who have sex with men (MSM) and pre-exposure prop…
View article: High Prevalence of Lower Extremity Medial Arterial Calcification in HIV-infected Patients With and Without Chronic Renal Disease: A Vascular Ultrasound Cross-sectional Study
High Prevalence of Lower Extremity Medial Arterial Calcification in HIV-infected Patients With and Without Chronic Renal Disease: A Vascular Ultrasound Cross-sectional Study Open
Background: The association between HIV infection and increased risk of atherosclerotic peripheral artery disease (PAD) has been documented. Still, the relationship between HIV infection and lower extremity medial arterial calcification (M…
View article: Evaluation of a multiplex real-time PCR assay for the diagnosis of sexually-transmitted infections
Evaluation of a multiplex real-time PCR assay for the diagnosis of sexually-transmitted infections Open
Diagnostic methods with simultaneous multi-targeting are applied for the accurate identification of sexually transmitted infections (STIs). The aim of this study was to evaluate a molecular real-time PCR-based assay (Vivalytic STI assay) f…
View article: <scp>HIV</scp> treatment strategies across Central, Eastern and Southeastern Europe: New times, old problems
<span>HIV</span> treatment strategies across Central, Eastern and Southeastern Europe: New times, old problems Open
Introduction In the last decade, substantial differences in the epidemiology of, antiretroviral therapy (ART) for, cascade of care in and support to people with HIV in vulnerable populations have been observed between countries in Western …
View article: Chronic Kidney Disease and Nephrology Care in People Living with HIV in Central/Eastern Europe and Neighbouring Countries—Cross-Sectional Analysis from the ECEE Network
Chronic Kidney Disease and Nephrology Care in People Living with HIV in Central/Eastern Europe and Neighbouring Countries—Cross-Sectional Analysis from the ECEE Network Open
Chronic kidney disease (CKD) is a significant cause of morbidity and mortality among patients infected with human immunodeficiency virus (HIV). The Central and East Europe (CEE) region consists of countries with highly diversified HIV epid…
View article: A cross‐sectional assessment of frailty, falls and perceptions of ageing in people living with<scp>HIV</scp>using an<scp>mHealth</scp>platform
A cross‐sectional assessment of frailty, falls and perceptions of ageing in people living with<span>HIV</span>using an<span>mHealth</span>platform Open
Objective To evaluate frailty, falls and perceptions of ageing among clinically stable individuals with HIV, engaged with remote healthcare delivered via a novel smartphone application. Methods This was a multi‐centre European c ross‐secti…
View article: Preliminary report on the provision of HIV care to war refugees with HIV who are migrating from Ukraine: data from the ECEE Network Group
Preliminary report on the provision of HIV care to war refugees with HIV who are migrating from Ukraine: data from the ECEE Network Group Open
The ECEE Network Group investigated early provision of HIV care to war refugees migrating from Ukraine in Central and Eastern Europe (CEE) through an online survey. Fourteen countries admitting war refugees from Ukraine on March 31, 2022, …
View article: Observational cohort study of rilpivirine (RPV) utilization in Europe
Observational cohort study of rilpivirine (RPV) utilization in Europe Open
View article: Correction: Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020
Correction: Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020 Open
[This corrects the article DOI: 10.1371/journal.pone.0263437.].
View article: The Management of HIV Care Services in Central and Eastern Europe: Data from the Euroguidelines in Central and Eastern Europe Network Group
The Management of HIV Care Services in Central and Eastern Europe: Data from the Euroguidelines in Central and Eastern Europe Network Group Open
Introduction: The COVID-19 pandemic has been challenging time for medical care, especially in the field of infectious diseases (ID), but it has also provided an opportunity to introduce new solutions in HIV management. Here, we investigate…
View article: The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group
The Presence of Either Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients from a Multinational Observational Study: Data from Euroguidelines in Central and Eastern Europe Network Group Open
HIV-positive patients may present lungs with multiple infections, which may hinder differential diagnoses and the choice of treatment in the course of COVID-19, especially in countries with limited access to high-standard healthcare. Here,…
View article: Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020
Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020 Open
Background During the initial phase of the COVID-19 pandemic, there was great enthusiasm for the use of azithromycin with or without hydroxychloroquine. Objectives We analyzed azithromycin consumption in Croatia in 2020 and compared this t…
View article: The Presence of Both Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients From a Multinational Observational Study: Data From Euroguidelines in Central and Eastern Europe Network Group
The Presence of Both Typical or Atypical Radiological Changes Predicts Poor COVID-19 Outcomes in HIV-Positive Patients From a Multinational Observational Study: Data From Euroguidelines in Central and Eastern Europe Network Group Open
View article: The cost of care for people living with stable HIV in Croatia and the efficiency of EmERGE
The cost of care for people living with stable HIV in Croatia and the efficiency of EmERGE Open
EmERGE Pathway was a cost-saving intervention associated with changes in management, and a reduction in outpatient visits, tests, and costs. ARV costs dominated costs. Future efficiencies are possible if EmERGE is introduced to other PLHIV…
View article: Hypersensitivity reactions, hepatotoxicity, and other discontinuations in persons receiving integrase strand transfer inhibitors: results from the EuroSIDA study
Hypersensitivity reactions, hepatotoxicity, and other discontinuations in persons receiving integrase strand transfer inhibitors: results from the EuroSIDA study Open
Background: Hypersensitivity reaction (HSR) and hepatotoxicity are rare, but potentially serious side-effects of antiretroviral use.Objective: To investigate discontinuations due to HSR, hepatotoxicity or other reasons among users of dolut…
View article: Hypersensitivity reactions, hepatotoxicity, and other discontinuations in persons receiving integrase strand transfer inhibitors: results from the EuroSIDA study
Hypersensitivity reactions, hepatotoxicity, and other discontinuations in persons receiving integrase strand transfer inhibitors: results from the EuroSIDA study Open
Background: Hypersensitivity reaction (HSR) and hepatotoxicity are rare, but potentially serious side-effects of antiretroviral use.Objective: To investigate discontinuations due to HSR, hepatotoxicity or other reasons among …
View article: Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020
Azithromycin consumption during the COVID-19 pandemic in Croatia, 2020 Open
Background During the initial phase of the COVID-19 pandemic, there was great enthusiasm for the use of azithromycin with or without hydroxychloroquine. Objectives We analyzed azithromycin consumption in Croatia in 2020 and compared this t…
View article: National strategies for vaccination against COVID‐19 in people living with HIV in Central and Eastern European region
National strategies for vaccination against COVID‐19 in people living with HIV in Central and Eastern European region Open
Introduction People living with HIV (PLWH) are at higher risk of poorer COVID‐19 outcomes. Vaccination is a safe and effective method of prevention against many infectious diseases, including COVID‐19. Here we investigate the strategies fo…