Jouri Alanazi
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View article: Nanotechnology Approaches for Mitigating Biologic Immunogenicity: A Literature Review
Nanotechnology Approaches for Mitigating Biologic Immunogenicity: A Literature Review Open
Biologic therapeutics, particularly monoclonal antibodies (mAbs), have revolutionized disease treatment paradigms; however, their clinical success is often hindered by immunogenicity. Host immune recognition of these biologics can induce a…
View article: Effect of C7-3-Peptide-Loaded Chitosan Nanoparticles Against Multi-Drug-Resistant Neisseria gonorrhoeae
Effect of C7-3-Peptide-Loaded Chitosan Nanoparticles Against Multi-Drug-Resistant Neisseria gonorrhoeae Open
All prepared NPs were optimized for the smallest particle size of 136.9 to 168.3 nm. The EE% of C7-3, C7-3m1, and C7-3m2 CNPs reached 90.2, 92.5, and 91.8%, respectively. An in vitro release study demonstrated a continuous sustained-releas…
View article: MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization Open
Choroidal neovascularization (CNV) is a major cause of visual impairment that results from excessive growth of blood vessels in the eye’s choroid. The limited clinical efficacy of the current therapy for this condition requires the emergen…
View article: Saudi Arabia stands as one of the leading countries for COVID-19 containment
Saudi Arabia stands as one of the leading countries for COVID-19 containment Open
Objective: Coronavirus disease 2019 (COVID-19) has emerged in China at the end of the year 2019 and a few weeks later it has out broken globally. There are obvious geographical variations in the mortality rates of COVID-19 according to the…
View article: Preparation, characterization, and antibacterial activity of diclofenac-loaded chitosan nanoparticles
Preparation, characterization, and antibacterial activity of diclofenac-loaded chitosan nanoparticles Open