Benjamin U. Ebeshi
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View article: Titrimetric and thin layer chromatographic fingerprint analysis of captopril solid dosage form – an Angiotensin- Converting Enzyme Inhibitor
Titrimetric and thin layer chromatographic fingerprint analysis of captopril solid dosage form – an Angiotensin- Converting Enzyme Inhibitor Open
Captopril is an angiotensin-converting enzyme inhibitor (ACEI), that prevents the conversion of Angiotensin I to Angiotensin II, thereby decreasing blood pressure by lowering peripheral vascular pressure without increasing cardiac output o…
View article: Spectroscopic In-Vitro Drug-Drug Interaction Studies of Amoxicillin and Paracetamol Solid Dosage Forms
Spectroscopic In-Vitro Drug-Drug Interaction Studies of Amoxicillin and Paracetamol Solid Dosage Forms Open
Potential drug-drug interactions (DDIs) are a public health concern in clinical therapy and drug development because of their contribution to actual adverse drug reactions (ADRs) or events. The study aimed to quantify the in-vitro drug-dru…
View article: Assessment of Secondary Metabolites and Thin-Layer Chromatographic Analysis of Carica papaya (Caricaceae) Leaves Ethanolic Extract
Assessment of Secondary Metabolites and Thin-Layer Chromatographic Analysis of Carica papaya (Caricaceae) Leaves Ethanolic Extract Open
Carica papaya, also referred to as pawpaw, is a tropical fruit-bearing tree in the Caricaceae family. Papaya is one of the world's most extensively grown crops. Its fruits, seeds, and leaves are widely utilized in cooking and traditional m…
View article: Evaluation of Stability and TLC Fingerprinting of the Artemether Component in Artemether-Lumefantrine Combination Suspension Formulations Available in Nigeria Pharmaceutical Market
Evaluation of Stability and TLC Fingerprinting of the Artemether Component in Artemether-Lumefantrine Combination Suspension Formulations Available in Nigeria Pharmaceutical Market Open
Aim: Artemether is the main component of the artemisinin-based combination therapy (ACT), used in the management of malaria infection caused by Plasmodium falciparum. Hence, its stability and conformation to pharmacopeia standards are nece…
View article: Genotyping of Uridine-Diphosphate Glucuronosyltransferases-1A1 (UGT1A1) Enzyme and Its Genetic Variant Allele Determination Using Polymerase Chain Reaction and Gel Electrophoresis
Genotyping of Uridine-Diphosphate Glucuronosyltransferases-1A1 (UGT1A1) Enzyme and Its Genetic Variant Allele Determination Using Polymerase Chain Reaction and Gel Electrophoresis Open
Dolutegravir is an integrase inhibitor that prevents the integration of the viral genome into the host cell’s DNA, thus halting HIV replication. The study aimed to conduct genotyping of immunocompromised patients in some Southern States of…
View article: Correlation Analysis of DNA UGT1A1 Gene Expression in Hyperbilirubinemia and Central Nervous System-Related Adverse Reactions Following Oral Dolutegravir Administration
Correlation Analysis of DNA UGT1A1 Gene Expression in Hyperbilirubinemia and Central Nervous System-Related Adverse Reactions Following Oral Dolutegravir Administration Open
Major pharmaceutical guidelines have identified Dolutegravir (DTG) as a critical medicine in the first-line treatment of HIV/AIDS. The goal of the study was to correlate DNA UGT1A1 gene expression in hyperbilirubinemia and central nervous …
View article: HEAVY METALS QUANTIFICATION AND CORRELATIVE CARCINOGENIC-RISKS EVALUATION IN SELECTED ENERGY DRINKS SOLD IN BAYELSA STATE USING ATOMIC ABSORPTION SPECTROSCOPIC TECHNIQUE
HEAVY METALS QUANTIFICATION AND CORRELATIVE CARCINOGENIC-RISKS EVALUATION IN SELECTED ENERGY DRINKS SOLD IN BAYELSA STATE USING ATOMIC ABSORPTION SPECTROSCOPIC TECHNIQUE Open
Objective: The study aimed to quantify the concentrations and carcinogenic-related health risks assessment of some heavy metals in selected energy drinks frequently utilized in Bayelsa State, Nigeria. Methods: Eleven energy drinks samples …
View article: Atomic Absorption Spectroscopic (AAS) Analysis of Heavy Metals and Health Risks Assessment of some Common Energy Drinks
Atomic Absorption Spectroscopic (AAS) Analysis of Heavy Metals and Health Risks Assessment of some Common Energy Drinks Open
Background and Purpose: Soft drinks are commonly consumed globally. Due to high demand, regulatory protocols may be breached thereby leading to contamination with heavy metals. In this study, we determined the content of five heavy metals …
View article: Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations
Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations Open
In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms as quickly as possible. Gastric contents are acidic; therefore, antacids are usually weak bases with the potential to neutralize excess acid and raise ga…
View article: Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations
Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations Open
In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms as quickly as possible. Gastric contents are acidic; therefore, antacids are usually weak bases with the potential to neutralize excess acid and raise ga…
View article: Spectroscopic Determination of Two Beta-Blockers – Atenolol and Propanolol by Oxidative Derivatization Using Potassium Permanganate in Alkaline Medium
Spectroscopic Determination of Two Beta-Blockers – Atenolol and Propanolol by Oxidative Derivatization Using Potassium Permanganate in Alkaline Medium Open
A simple, rapid, sensitive, cheap and accurate oxidative method for two beta-blockers in pharmaceutical dosage forms was developed and evaluated. The method involved the oxidimetric treatment of atenolol and propanolol with 2 x 10-3 mol L-…
View article: Measurement, reporting and verification of climate-smart agriculture: Change of perspective, change of possibilities?
Measurement, reporting and verification of climate-smart agriculture: Change of perspective, change of possibilities? Open
The World Agroforestry Centre (ICRAF), Unique Forestry and Land Use and Vuna have been working with stakeholders in four countries in eastern and southern Africa (Tanzania, Malawi, Zambia and Zimbabwe) to assess the current state of nation…