Wei Liu
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View article: Stratified dosimetric comparison between high‐definition multileaf collimator‐based D2SRS and robotic radiosurgery in the treatment of brain metastases
Stratified dosimetric comparison between high‐definition multileaf collimator‐based D2SRS and robotic radiosurgery in the treatment of brain metastases Open
Purpose To compare dosimetric characteristics and treatment efficiency between the high‐definition multileaf collimator (HD‐MLC) system and robotic radiosurgery (RRS) for brain metastases, with stratified analysis by lesion count. Methods …
View article: Robotic-assisted and electromagnetic navigation bronchoscopy for multi-focal lung cancers: a narrative review
Robotic-assisted and electromagnetic navigation bronchoscopy for multi-focal lung cancers: a narrative review Open
View article: Ultrasound combined computed tomography angiography for prognosis prediction in free posterior interosseous artery perforator flap surgery
Ultrasound combined computed tomography angiography for prognosis prediction in free posterior interosseous artery perforator flap surgery Open
View article: Clinical Outcomes of Transanal Drainage Tube Placement Following Surgical Repair for Chronic III-IV Perineal Tears
Clinical Outcomes of Transanal Drainage Tube Placement Following Surgical Repair for Chronic III-IV Perineal Tears Open
Transanal drainage tube placement may enhance anal sphincter function when used at the time of anal sphincteroplasty. Maintaining TDT for more than 8 days is associated with higher success rate. Both successful and unsuccessful repairs lea…
View article: The predictive value of a body shape index as a novel obesity metric for cancer risk: a systematic review and meta-analysis
The predictive value of a body shape index as a novel obesity metric for cancer risk: a systematic review and meta-analysis Open
Background The A Body Shape Index (ABSI), a metric assessing visceral adiposity distribution by integrating height, weight, and waist circumference (WC), remains a subject of debate regarding its predictive value for diverse cancer risks. …
View article: Role of Endobronchial Navigation in Lung Cancer Management
Role of Endobronchial Navigation in Lung Cancer Management Open
The landscape of lung cancer management is undergoing a transformative paradigm shift, shifting from the traditional focus on solitary tumors to the recognition and treatment of small, multifocal, ground-glass lesions—a change driven predo…
View article: A meta analysis of subtype-specific prognostic significance of METTL3 expression in non-small cell lung cancer
A meta analysis of subtype-specific prognostic significance of METTL3 expression in non-small cell lung cancer Open
Objective: This study aimed to systematically synthesize evidence regarding the association between METTL3 expression and clinical outcomes in patients with non-small-cell lung cancer (NSCLC). Methods: A comprehensive literature search was…
View article: Enhancing the regulatory effect of LY9 on breast cancer microenvironment through a nanodelivery system
Enhancing the regulatory effect of LY9 on breast cancer microenvironment through a nanodelivery system Open
View article: microRNA-196b-5p expression in cancer tissues is closely associated with clinical and pathological characteristics and prognosis of patients with non-small cell lung cancer
microRNA-196b-5p expression in cancer tissues is closely associated with clinical and pathological characteristics and prognosis of patients with non-small cell lung cancer Open
High miR-196b-5p expression in cancer tissues of NSCLC patients was closely linked to capsule invasion, LNM, maximum tumor diameter, and clinical TNM stage and was an IRF for 3-year postoperative mortality in NSCLC patients.
View article: Robotic-assisted bronchoscopy—advancing lung cancer management
Robotic-assisted bronchoscopy—advancing lung cancer management Open
The incidental discovery of early-stage, multifocal lung cancer is transforming the medical landscape. Diagnosing and treating such lesions are often troublesome due to their small size, subsolid consistency, and multifocal nature. This ha…
View article: 820 | PHASE 2 STUDY OF DZD8586, A NON‐COVALENT BBB PENETRANT LYN/BTK DUAL INHIBITOR, AS MONOTHERAPY IN RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA: TAI‐SHAN9 TRIAL
820 | PHASE 2 STUDY OF DZD8586, A NON‐COVALENT BBB PENETRANT LYN/BTK DUAL INHIBITOR, AS MONOTHERAPY IN RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA: TAI‐SHAN9 TRIAL Open
View article: RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners Open
Oral squamous cell carcinoma (OSCC) progresses from epithelial cell proliferation to malignancy. Given the higher proportion of male patients compared to female patients, the androgen signaling pathway is believed to play a significant rol…
View article: A systematic review and meta-analysis of artificial intelligence software for tuberculosis diagnosis using chest X-ray imaging
A systematic review and meta-analysis of artificial intelligence software for tuberculosis diagnosis using chest X-ray imaging Open
AI software has demonstrated excellent diagnostic performance in assisting the CXR diagnosis of TB and can help clinicians to make rapid and accurate decisions in screening and treating patients with TB.
View article: Instruction multi-constraint molecular generation using a teacher-student large language model
Instruction multi-constraint molecular generation using a teacher-student large language model Open
View article: Unraveling the role of CLOCK gene in fibrotic skin diseases: insights from single-cell RNA sequencing analysis
Unraveling the role of CLOCK gene in fibrotic skin diseases: insights from single-cell RNA sequencing analysis Open
Fibrosis, characterized by excessive extracellular matrix (ECM) accumulation and fibroblast proliferation, significantly contributes to global morbidity and mortality, affecting millions worldwide. Despite its prevalence, the mechanisms un…
View article: OASL as a novel prognostic biomarker associated with immune infiltrates in ccRCC
OASL as a novel prognostic biomarker associated with immune infiltrates in ccRCC Open
View article: Magnetic Bead Ingestion in a Pediatric Patient: Imaging and Management
Magnetic Bead Ingestion in a Pediatric Patient: Imaging and Management Open
View article: Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives
Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives Open
Drug-induced liver injury (DILI) results from the liver toxicity caused by drugs or their metabolites. Gallic acid (GA) is a naturally occurring secondary metabolite found in many fruits, plants, and nuts. Recently, GA has drawn increasing…
View article: Synthesis and Biological Evaluation of Quercetagetin Derivatives as the Inhibitors of Mcl-1 and Bcl-2 Against Leukemia
Synthesis and Biological Evaluation of Quercetagetin Derivatives as the Inhibitors of Mcl-1 and Bcl-2 Against Leukemia Open
B-cell lymphoma-2 (Bcl-2) family proteins are fundamental regulators of intrinsic cell apoptosis, and overexpression of apoptotic proteins (Bcl-2 and Mcl-1) is a characteristic of many haematological malignancies. Thus, it is necessary to …
View article: A Novel Percutaneous Volume Reduction Technique for Giant Emphysematous Bullae: Combined Percutaneous Erythromycin Sclerotherapy With Bronchoscopic Occlusion
A Novel Percutaneous Volume Reduction Technique for Giant Emphysematous Bullae: Combined Percutaneous Erythromycin Sclerotherapy With Bronchoscopic Occlusion Open
The novel percutaneous bulla volume reduction technique represents a safe and effective non-surgical alternative for patients with inoperable GEB, demonstrating sustained therapeutic benefits lasting at least six months. The procedure appe…
View article: Association between a body shape index and colorectal cancer in US population: a cross-sectional study based on NHANES
Association between a body shape index and colorectal cancer in US population: a cross-sectional study based on NHANES Open
Background Colorectal cancer (CRC) is linked to obesity, particularly visceral fat. A more accurate measure of visceral fat accumulation is offered by a body shape index (ABSI). Currently, the direct application of the ABSI to populations …
View article: Bruceine a Abrogates Pancreatic Cancer Metastasis Via Targeting Pfkfb4-Glycolysis-Emt Axis
Bruceine a Abrogates Pancreatic Cancer Metastasis Via Targeting Pfkfb4-Glycolysis-Emt Axis Open
View article: Integrative Machine Learning of Glioma and Coronary Artery Disease Reveals Key Tumour Immunological Links
Integrative Machine Learning of Glioma and Coronary Artery Disease Reveals Key Tumour Immunological Links Open
It is critical to appreciate the role of the tumour‐associated microenvironment (TME) in developing strategies for the effective therapy of cancer, as it is an important factor that determines the evolution and treatment response of tumour…
View article: OVERVIEW OF CLASS-I TRIPARTITE MOTIF (TRIM) PROTEINS SPECIFICALLY TRIM67
OVERVIEW OF CLASS-I TRIPARTITE MOTIF (TRIM) PROTEINS SPECIFICALLY TRIM67 Open
The TRIM family is a group of genes expressed during embryogenesis. This review emphasized data on Class-I TRIM genes, including TRIM1, TRIM9, TRIM36, TRIM46, TRIM67, TRIM18, and TRIM76. This article will discuss the structure and function…
View article: Incomplete Immunity for Varicella and Measles in Pediatric Organ Transplant Candidates. Real World Experience From an Infectious Diseases Pre‐Transplantation Clinic
Incomplete Immunity for Varicella and Measles in Pediatric Organ Transplant Candidates. Real World Experience From an Infectious Diseases Pre‐Transplantation Clinic Open
Background Vaccinating pediatric solid organ transplant candidates against measles and varicella is crucial due to the risk of severe disease in immunosuppressed recipients and general avoidance of live virus vaccines post‐transplantation.…
View article: Optimized Machine Learning Models for Predicting Core Body Temperature in Dairy Cows: Enhancing Accuracy and Interpretability for Practical Livestock Management
Optimized Machine Learning Models for Predicting Core Body Temperature in Dairy Cows: Enhancing Accuracy and Interpretability for Practical Livestock Management Open
Heat stress poses a significant challenge to livestock farming, particularly affecting the health and productivity of high-yield dairy cows. This study develops a machine learning framework aimed at predicting the core body temperature (CB…
View article: Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer Open
View article: Role of mitophagy in head and neck squamous cell carcinoma: Prognosis and immune insights
Role of mitophagy in head and neck squamous cell carcinoma: Prognosis and immune insights Open
Objective: To explore the correlation between mitophagy and the tumor microenvironment (TME) in patients with head and neck squamous cell carcinoma (HNSCC), with an aim to enhance therapeutic efficacy for HNSCC. Methods: A machine learning…
View article: Case report: Primary sarcoma of the mandible with a novel SLMAP-BRAF fusion
Case report: Primary sarcoma of the mandible with a novel SLMAP-BRAF fusion Open
Primary sarcomas of the jaw are very rare tumor with unclear mechanism of tumorigenesis. Identification of genetic alterations contributes to better understanding of tumorigenesis and extension of tumor spectrum, as well as potential thera…
View article: RNA-RBP interactions recognition using multi-label learning and feature attention allocation
RNA-RBP interactions recognition using multi-label learning and feature attention allocation Open
In this study, we present a sophisticated multi-label deep learning framework for the prediction of RNA-RBP (RNA-binding protein) interactions, a critical aspect in understanding RNA functionality modulation and its implications in disease…