Ju‐Hee Seo
YOU?
Author Swipe
View article: Trends and Sociodemographic Characteristics of Nontuberculous Mycobacterial Infections in South Korea: A Nationwide NHIS-Based Study (2010–2022)
Trends and Sociodemographic Characteristics of Nontuberculous Mycobacterial Infections in South Korea: A Nationwide NHIS-Based Study (2010–2022) Open
NTM infection is increasing in Korea, with distinct epidemiologic patterns by sex, age, and socioeconomic status. The rising burden, especially among young women and the socioeconomically disadvantaged, warrants targeted public health stra…
View article: Longitudinal Trajectories of Asthma and Allergic Comorbidities in the Korean Childhood Asthma Study
Longitudinal Trajectories of Asthma and Allergic Comorbidities in the Korean Childhood Asthma Study Open
The longitudinal trajectories of asthma and allergic comorbidities in Korean children can be classified into distinct clusters. Most phenotypes exhibited early-onset asthma with a varying prevalence of comorbidities. The persistence of AD,…
View article: Pet Ownership Increases the Exhaled Nitric Oxide and Asthma Severity in Children With Atopic Asthma
Pet Ownership Increases the Exhaled Nitric Oxide and Asthma Severity in Children With Atopic Asthma Open
Exposure to pets can trigger symptoms in asthmatic children sensitized to pets. However, little is known about the association between pet ownership and asthma morbidity in children who are not sensitized to pets. We aimed to investigate t…
View article: Real-time portable muography with Hankuk Atmospheric-muon Wide Landscaping : HAWL
Real-time portable muography with Hankuk Atmospheric-muon Wide Landscaping : HAWL Open
Cosmic ray muons prove valuable across various fields, from particle physics experiments to non-invasive tomography, thanks to their high flux and exceptional penetrating capability. Utilizing a scintillator detector, one can effectively s…
View article: Influences of Health Interest, Sleep Quality, and Intention to Participate in Exercise on Having a Health-promoting Lifestyle in College Students: Based on Smartwatch Users and Non-users
Influences of Health Interest, Sleep Quality, and Intention to Participate in Exercise on Having a Health-promoting Lifestyle in College Students: Based on Smartwatch Users and Non-users Open
본 연구는 대학생을 대상으로 건강관심도, 수면의 질, 운동참여의도 및 건강증진 생활양식의 연관성을 살펴보고, 스마트워치 사용자와 비사용자를 비교하여 스마트워치 사용이 건강증진 생활양식에 미치는 영향을 파악하고자 진행되었다. 연구대상자는 서울에 소재한 4년제 대학교에 재학 중인 대학생으로, 온라인 설문조사를 통해 206명이 참여하였다. 연구결과, 대학생의 건강관심도와 운동참여의도는 건강증진 생활양식과 유의한 정적 상관관계를 보…
View article: Analysis of national surveillance of respiratory pathogen for children and adolescents' community acquired pneumonia
Analysis of national surveillance of respiratory pathogen for children and adolescents' community acquired pneumonia Open
Introduction: Respiratory infection in particular community acquired pneumonia (CAP) in children is a major disease that ranks high in outpatient and inpatient cases. The causes of CAP vary depending on the individual susceptibility, epide…
View article: Atmospheric environment and persistence of pediatric asthma: A population-based cohort study
Atmospheric environment and persistence of pediatric asthma: A population-based cohort study Open
We discovered various independent risk factors for the persistence of childhood asthma. By linking HIRA claims data, we could clarify risk factors for persistence in a well-defined study population.
View article: Fetal growth rather than prematurity determines lung function in children with asthma
Fetal growth rather than prematurity determines lung function in children with asthma Open
Background and Objective Preterm birth or fetal growth has been associated with reduced lung function and asthma during childhood in the general population. We aimed to elucidate whether prematurity or fetal growth has a significant influe…
View article: In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor
In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor Open
Despite genetic perturbations resulting in embryo lethality for most mitotic kinases, loss of the histone H3 mitotic kinase HASPIN reveals no adverse effect in mice models, establishing HASPIN as a promising target for anticancer therapy. …
View article: The association between MTHFR polymorphism, dietary methyl donors, and childhood asthma and atopy
The association between MTHFR polymorphism, dietary methyl donors, and childhood asthma and atopy Open
High intakes of dietary methyl donors were associated with reduced risk of atopy and asthma symptoms. These may have additive effects related to the susceptibility alleles of the MTHFR gene. The clinical implications require evaluation.
View article: Clinical Manifestations and Genotype of Primary Ciliary Dyskinesia Diagnosed in Korea: Multicenter Study
Clinical Manifestations and Genotype of Primary Ciliary Dyskinesia Diagnosed in Korea: Multicenter Study Open
To our knowledge, this is the first multicenter study to report the clinical characteristics, diagnostic methods, and genotypes of PCD in Korea. These results can be used as basic data for further PCD research.
View article: Clinical characteristics of pediatric patients infected with SARS-CoV-2 versus common human coronaviruses: a national multicenter study
Clinical characteristics of pediatric patients infected with SARS-CoV-2 versus common human coronaviruses: a national multicenter study Open
Background: Human coronaviruses (HCoV) cause mild upper respiratory infections; however, in 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged, causing an acute respiratory disease pandemic. Co…
View article: Assessment of variables associated with prolonged admission duration in children with <scp><i>Mycoplasma pneumoniae</i></scp> pneumonia
Assessment of variables associated with prolonged admission duration in children with <span><i>Mycoplasma pneumoniae</i></span> pneumonia Open
Introduction Macrolide‐resistant Mycoplasma pneumoniae (MRMP) has become prevalent in children. This study investigated the clinical and laboratory variables of MRMP and macrolide‐sensitive M. pneumoniae (MSMP) and identified factors assoc…
View article: Usefulness of ultrasonography in diagnosis of intestinal obstruction by a water bead
Usefulness of ultrasonography in diagnosis of intestinal obstruction by a water bead Open
Water beads are dangerous foreign bodies causing intestinal obstruction in young children because the beads absorb water and are radiolucent. Although the features lead to progressive intestinal obstruction, it is difficult to diagnose ing…
View article: Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor
Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor Open
Background: HASPIN, a mitotic kinase for Histone H3, is a promising target for anti-cancer therapy. However, as HASPIN is an atypical kinase with low similarity to eukaryotic protein kinases, development of a HASPIN inhibitor from the conv…
View article: Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor
Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor Open
Summary Background HASPIN, a mitotic kinase for Histone H3, is a promising target for anti-cancer therapy. However, as HASPIN is an atypical kinase with low similarity to eukaryotic protein kinases, development of a HASPIN inhibitor from t…
View article: Clinical manifestations and genotype of primary ciliary dyskinesia diagnosed in Korea: a nationwide, multicenter, retrospective study
Clinical manifestations and genotype of primary ciliary dyskinesia diagnosed in Korea: a nationwide, multicenter, retrospective study Open
Background: Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder that leads to secondary ciliary dysfunction. PCD is a rare disease worldwide, and its data are limited in Korea. This study systematically evaluated the c…
View article: Analysis of national surveillance of respiratory pathogens for community-acquired pneumonia in children and adolescents
Analysis of national surveillance of respiratory pathogens for community-acquired pneumonia in children and adolescents Open
Background Respiratory infections among children, particularly community-acquired pneumonia (CAP), is a major disease with a high frequency among outpatient and inpatient visits. The causes of CAP vary depending on individual susceptibilit…
View article: Clinical Characteristics of Macrolide-Refractory Mycoplasma pneumoniae Pneumonia in Korean Children: A Multicenter Retrospective Study
Clinical Characteristics of Macrolide-Refractory Mycoplasma pneumoniae Pneumonia in Korean Children: A Multicenter Retrospective Study Open
Mycoplasma pneumoniae is a major causative pathogen of community-acquired pneumonia in children, and the treatment of choice is macrolides. There is an increasing trend in reports of refractory clinical responses despite macrolide treatmen…
View article: The incidence and risk factors of extrapulmonary manifestations in<i>Mycoplasma pneumoniae</i>pneumonia
The incidence and risk factors of extrapulmonary manifestations in<i>Mycoplasma pneumoniae</i>pneumonia Open
Purpose\nMycoplasma pneumoniae pneumonia (MP) is a major cause of community-acquired pneumonia (CAP) in children and is associated with extrapulmonary manifestations (EPM). The incidence and risk factors for EPM in children are unknown.\n\…
View article: Serum high-mobility group box 1 protein level correlates with the lowest SaO2 in patients with sleep apnea: a preliminary study
Serum high-mobility group box 1 protein level correlates with the lowest SaO2 in patients with sleep apnea: a preliminary study Open
Introduction: Serum level of high-mobility group box 1 protein is reportedly correlated with the severity of obstructive sleep apnea. Objective: We tried to evaluate the possibility of using the serum high-mobility group box 1 protein leve…
View article: The Incidence and Risk Factors of Extrapulmonary Manifestations in Mycoplasma Pneumoniae Pneumonia
The Incidence and Risk Factors of Extrapulmonary Manifestations in Mycoplasma Pneumoniae Pneumonia Open
Background: Mycoplasma pneumoniae pneumonia (MP) is a major cause of community acquired pneumonia (CAP) in children and it is known to be associated with extrapulmonary manifestations (EPM). The incidence and risk factors of EPM in childre…
View article: Analysis of National Surveillance of Respiratory Pathogen for Children and Adolescents’ Community Acquired Pneumonia
Analysis of National Surveillance of Respiratory Pathogen for Children and Adolescents’ Community Acquired Pneumonia Open
Background : Respiratory infection in particular community acquired pneumonia (CAP) in children is a major disease that ranks high in outpatient and inpatient cases. The causes of CAP vary depending on the individual susceptibility, epidem…
View article: Successful Treatment of Severe Hemolytic Disease of the Newborn Caused by Anti-Jk<sup>b</sup>
Successful Treatment of Severe Hemolytic Disease of the Newborn Caused by Anti-Jk<sup>b</sup> Open
Hemolytic disease of the newborn (HDN) is a condition in which maternal antibodies cross the placenta and cause hemolytic reactions. Anti-RhD was the most common cause, but with the introduction of immunoglobulin, the frequency has decreas…
View article: Heterogeneity of Childhood Asthma in Korea: Cluster Analysis of the Korean Childhood Asthma Study Cohort
Heterogeneity of Childhood Asthma in Korea: Cluster Analysis of the Korean Childhood Asthma Study Cohort Open
The asthma phenotypes among Korean children can be classified into 4 distinct clusters. Long-term follow-up with these phenotypes will be needed to define their prognosis and response to treatment.
View article: Clinical Characteristics and Viral RNA Detection in Children With Coronavirus Disease 2019 in the Republic of Korea
Clinical Characteristics and Viral RNA Detection in Children With Coronavirus Disease 2019 in the Republic of Korea Open
In this case series study, inapparent infections in children may have been associated with silent COVID-19 transmission in the community. Heightened surveillance using laboratory screening will allow detection in children with unrecognized…
View article: Annual and seasonal patterns in etiologies of pediatric community-acquired pneumonia due to respiratory viruses and Mycoplasma pneumoniae requiring hospitalization in South Korea
Annual and seasonal patterns in etiologies of pediatric community-acquired pneumonia due to respiratory viruses and Mycoplasma pneumoniae requiring hospitalization in South Korea Open
Background: Community–acquired pneumonia (CAP) is one of the leading worldwide causes of childhood morbidity and mortality. Its disease burden varies by age and etiology and is time dependent. We aimed to investigate the annual and seasona…
View article: Risk factors for the development of asthma symptoms in children with allergic rhinitis
Risk factors for the development of asthma symptoms in children with allergic rhinitis Open
Purpose: Both allergic rhinitis and asthma are considered one airway disease, which interacts with each other in disease onset and symptom worsening. We evaluated factors developing new or persistent asthma symptoms in elementary school ch…
View article: COVID-19 in children across three Asian cosmopolitan regions
COVID-19 in children across three Asian cosmopolitan regions Open
ABSTRACT As another wave of COVID-19 outbreak has approached in July 2020, a larger scale COVID-19 pediatric Asian cohort summarizing the clinical observations is warranted. Children confirmed with COVID-19 infection from the Republic of K…