Ju Sun Heo
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View article: Breast milk microbiome shapes early-life immunity and protects against neonatal sepsis 3370
Breast milk microbiome shapes early-life immunity and protects against neonatal sepsis 3370 Open
Description The development of the microbiome in neonates is influenced by various factors, including breastfeeding and antibiotic exposure, which have implications for conditions such as necrotizing enterocolitis (NEC) and sepsis. Clinica…
View article: Short-term and long-term effects of vitamin D supplementation for preterm infants: a systematic review and meta-analysis
Short-term and long-term effects of vitamin D supplementation for preterm infants: a systematic review and meta-analysis Open
Meta-analysis conducted to evaluate the effectiveness of high-dose (≥800 IU/day) and low-dose (<800 IU/day) vitamin D supplementation on preterm infants. Study quality was evaluated using the Revised Cochrane risk-of-bias tool 2 for random…
View article: Respiratory severity score-guided postnatal systemic corticosteroid therapy for bronchopulmonary dysplasia in extremely preterm infants
Respiratory severity score-guided postnatal systemic corticosteroid therapy for bronchopulmonary dysplasia in extremely preterm infants Open
Background: Bronchopulmonary dysplasia (BPD) is a major complication in extremely preterm (EP) infants. Postnatal systemic corticosteroids reduce inflammation and may help prevent or treat BPD. However, their use is limited because of conc…
View article: Sex‐Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data
Sex‐Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data Open
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder influenced by genetic, epigenetic, and environmental factors. ASD is characterized by a higher prevalence in males compared to females, highlighting the potential role…
View article: Palivizumab coverage rates among moderate-to-late preterm infants in Korea: a nationwide cross-sectional study
Palivizumab coverage rates among moderate-to-late preterm infants in Korea: a nationwide cross-sectional study Open
OBJECTIVES: Since October 2016, Korea has implemented a national reimbursement program for palivizumab aimed at moderate-to-late preterm (MLPT) infants born between 32 0/7 weels and 35 6/7 weeks of gestation during the respiratory syncytia…
View article: Deep-Learning-Based Multi-Class Classification for Neonatal Respiratory Diseases on Chest Radiographs in Neonatal Intensive Care Units
Deep-Learning-Based Multi-Class Classification for Neonatal Respiratory Diseases on Chest Radiographs in Neonatal Intensive Care Units Open
Introduction: Accurate and timely interpretation of chest radiographs is essential for assessing respiratory distress and guiding clinical management to improve outcomes of critically ill newborns. This study aimed to introduce a deep-lear…
View article: Strategies to support language development in neonatal intensive care unit: a narrative review
Strategies to support language development in neonatal intensive care unit: a narrative review Open
Despite neonatal intensive care advancements and quality improvements, preterm infants often experience delays in speech and language development during early childhood. The etiological pathway of language delays is multifactorial, includi…
View article: Clinical and dental predictors of preterm birth using machine learning methods: the MOHEPI study
Clinical and dental predictors of preterm birth using machine learning methods: the MOHEPI study Open
Preterm birth (PTB) is one of the most common and serious complications of pregnancy, leading to mortality and severe morbidities that can impact lifelong health. PTB could be associated with various maternal medical condition and dental s…
View article: A prospective, observational, multi-center, post-marketing safety surveillance study of the GSK combined vaccine against diphtheria, tetanus, pertussis, poliomyelitis, and <i>Haemophilus influenzae</i> type b invasive infections (DTaP-IPV/Hib) in South Korean infants
A prospective, observational, multi-center, post-marketing safety surveillance study of the GSK combined vaccine against diphtheria, tetanus, pertussis, poliomyelitis, and <i>Haemophilus influenzae</i> type b invasive infections (DTaP-IPV/Hib) in South Korean infants Open
In South Korea, a combined vaccine against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b invasive infections (DTaP-IPV/Hib) is available since 2018 for vaccination of infants from the age of 2 months. Thi…
View article: Differences in maternal subgingival microbiome between preterm and term births: The MOHEPI study
Differences in maternal subgingival microbiome between preterm and term births: The MOHEPI study Open
Aim Periodontitis is a potential risk factor for preterm birth (PTB) in women; however, the causal relationship or the exact mechanism remain unknown. This study aimed to compare the oral microbiome features of mothers with full‐term birth…
View article: Risk factors and outcomes of vitamin D deficiency in very preterm infants
Risk factors and outcomes of vitamin D deficiency in very preterm infants Open
Prolonged PN duration and low breast milk intake significantly increased the risk of VDD in VP infants.
View article: Prepregnancy and prenatal risk factors for the neurodevelopmental delay of offspring: Machine learning analysis using national health insurance claims data
Prepregnancy and prenatal risk factors for the neurodevelopmental delay of offspring: Machine learning analysis using national health insurance claims data Open
Neurodevelopmental disorders (NDD) in offspring are associated with a complex combination of pre-and postnatal factors. This study uses machine learning and population data to evaluate the association between prepregnancy or prenatal predi…
View article: Survival and Risk Factors for Mortality in Infants With Congenital Heart Disease in South Korea
Survival and Risk Factors for Mortality in Infants With Congenital Heart Disease in South Korea Open
The survival of infants with CHD has been favorable in South Korea. Several neonatal conditions are risk factors for childhood mortality. Individualized risk assessment and optimal treatment strategies may help improve their survival rate.
View article: Impact of Palivizumab in Preventing Severe Acute Lower Respiratory Infection in Moderate-to-Late Preterm Infants: A Nationwide Cohort Study
Impact of Palivizumab in Preventing Severe Acute Lower Respiratory Infection in Moderate-to-Late Preterm Infants: A Nationwide Cohort Study Open
The risks of severe ALRI outcomes decreased in Korea following the 2016 insurance implementation of palivizumab prophylaxis for MLPT infants born during the RSV season with older siblings.
View article: Expert opinion on evidence after the 2020 Korean Cardiopulmonary Resuscitation Guidelines: a secondary publication
Expert opinion on evidence after the 2020 Korean Cardiopulmonary Resuscitation Guidelines: a secondary publication Open
Considerable evidence has been published since the 2020 Korean Cardiopulmonary Resuscitation Guidelines were reported. The International Liaison Committee on Resuscitation (ILCOR) also publishes the Consensus on CPR and Emergency Cardiovas…
View article: Epidemiology of Catheter-related Bloodstream Infections in Neonatal Intensive Care Units: A Rapid Systematic Literature Review
Epidemiology of Catheter-related Bloodstream Infections in Neonatal Intensive Care Units: A Rapid Systematic Literature Review Open
Central venous catheters are commonly used to admin-ister medications and parenteral nutrition to vulnerable neonates in neonatal intensive care units (NICUs) [1].A common and serious complication of central venous cath-
View article: COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data
COVID-19 and vaccination during pregnancy: a systematic analysis using Korea National Health Insurance claims data Open
ObjectiveThis study systematically analyzed coronavirus disease 2019 (COVID-19) and vaccination details during pregnancy by using the national health insurance claims data.MethodsPopulation-based retrospective cohort data of 12,399,065 wom…
View article: Survey of Korean pediatrician’s perceptions of barriers to and improvements in breastfeeding
Survey of Korean pediatrician’s perceptions of barriers to and improvements in breastfeeding Open
Background: Although the benefits of breastfeeding are broadly acknowledged with the efforts of the government and several medical societies, the rate of exclusive breastfeeding through 6 months is lower in Korea than in developed countrie…
View article: Survey on the Status of Breastfeeding in Korean Medical Institution Workers
Survey on the Status of Breastfeeding in Korean Medical Institution Workers Open
In medical institutions, it is recommended that environmental improvements in medical institutions, the implementation of supporting policies, and the provision of specialized education on breastfeeding are necessary to promote breastfeedi…
View article: Breastfeeding and vitamin D
Breastfeeding and vitamin D Open
The recent re-emergence of vitamin D deficiency (VDD) and rickets among breastfed infants without adequate sunlight exposure and vitamin D supplementation has been reported worldwide. Breastfed infants are particularly vulnerable to VDD be…
View article: Preventive Intervention Program on the Outcomes of Very Preterm Infants and Caregivers: A Multicenter Randomized Controlled Trial
Preventive Intervention Program on the Outcomes of Very Preterm Infants and Caregivers: A Multicenter Randomized Controlled Trial Open
Increased survival in the very preterm population results in a higher risk of developing neurodevelopmental and behavioral disabilities among survivors. We examined the outcomes of very preterm infants and parents after a preventive interv…
View article: The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis
The Long-Term Effect of Preterm Birth on Renal Function: A Meta-Analysis Open
The preterm-born adult population is ever increasing following improved survival rates of premature births. We conducted a meta-analysis to investigate long-term effects of preterm birth on renal function in preterm-born survivors. We sear…
View article: Trisomy 9 Mosaicism in an Extremely Low Birth Weight Infant
Trisomy 9 Mosaicism in an Extremely Low Birth Weight Infant Open
Trisomy 9 mosaicism is a rare chromosomal abnormality with distinct and recognizable clinical features. In this report, we present an extremely low birth weight (ELBW) infant with trisomy 9 mosaicism. A male preterm infant born at 31+3 wee…