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View article: Predictors of response to omalizumab for chronic spontaneous urticaria: a retrospective audit on a rural and regional patient cohort in Darwin, Australia
Predictors of response to omalizumab for chronic spontaneous urticaria: a retrospective audit on a rural and regional patient cohort in Darwin, Australia Open
This review of omalizumab use in chronic spontaneous urticaria (CSU) over a 9‐year period in a rural setting identified that a ‘complete response’ to 3 months of omalizumab treatment was associated with an elevated IgE level, absence of ot…
View article: Corrigendum to “Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea” [Bioact. Mater. 2023 (8) 29 265–278]
Corrigendum to “Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea” [Bioact. Mater. 2023 (8) 29 265–278] Open
[This corrects the article DOI: 10.1016/j.bioactmat.2023.07.005.].
View article: In Vivo Synthesis of Metabolically Degradable π‑Conjugated Conductive Polymers Enabling Seamless Neural Interface Integration and Tissue Repair
In Vivo Synthesis of Metabolically Degradable π‑Conjugated Conductive Polymers Enabling Seamless Neural Interface Integration and Tissue Repair Open
The seamless integration of bioelectronics with neural tissues is essential for regulating biological signal transmission and understanding complex physiological functions. However, conventional bioelectronic materials face significant lim…
View article: Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction Open
Post‐myocardial infarction (MI), the rapid decrease in pH triggers myocardial cell acidosis, which compromises the therapeutic efficacy of exosomes in MI. The groundbreaking research in the human cardiac organoid MI model suggests that exo…
View article: An Improved Crayfish Algorithm‐Based Neural Network Method for Modeling Microstrip Patch Antennas
An Improved Crayfish Algorithm‐Based Neural Network Method for Modeling Microstrip Patch Antennas Open
Artificial neural networks (ANNs) have shown remarkable advantages in antenna modeling and optimization as surrogate models. However, in single‐objective modeling, the convergence accuracy of ANN‐based antenna models is often insufficient.…
View article: A rare case of appendiceal haemorrhage causing life-threatening haematochezia
A rare case of appendiceal haemorrhage causing life-threatening haematochezia Open
Our case involved a 28-year-old man who presented with life-threatening haematochezia. Computed tomography angiogram revealed contrast extravasation from the appendix pooling in the caecum. Management via laparoscopic stapled partial caece…
View article: OR08-01 Serum Testosterone, Age, Waist Circumference and Glycaemia and Risk of Incident Type 2 Diabetes in an Urban Community of Middle Aged and Older Men.
OR08-01 Serum Testosterone, Age, Waist Circumference and Glycaemia and Risk of Incident Type 2 Diabetes in an Urban Community of Middle Aged and Older Men. Open
M. Umapathysivam: None. A. Vincent: None. J. Tan: None. A. Ashagre: None. D. Jesudason: None. G. Wittert: Consulting Fee; Self; I-Nova. Grant Recipient; Self; Bayer, Inc., Eli Lilly & Company, Weight Watchers, Lawley Pharmaceutical. Speake…
View article: Author response: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Author response: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states Open
Full text Figures and data Peer review Side by side Abstract eLife assessment Introduction Results Discussion Materials and methods Appendix 1 Data availability References Article and author information Metrics Abstract While accumulated p…
View article: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Author Response: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Author Response: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Reviewer #2 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Reviewer #2 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Author Response: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Author Response: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Reviewer #1 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Reviewer #1 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators into acellular blood vessels
Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators into acellular blood vessels Open
Small-diameter tissue-engineered vascular grafts (sdTEVGs) have garnered significant attention as a potential treatment modality for vascular bypass grafting and replacement therapy. However, the intimal hyperplasia and thrombosis are two …
View article: Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission
Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission Open
M6A modification is an RNA-important processing event mediated by methyltransferases METTL3 and METTL14 and the demethylases. M6A dynamic changes after myocardial infarction (MI), involved in the massive loss of cardiomyocytes due to hypox…
View article: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
Summary While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our gen…
View article: Author Response: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Author Response: Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Reviewer #1 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Reviewer #1 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Reviewer #2 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Reviewer #2 (Public Review): Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury Open
While accumulated publications support the existence of neurogenesis in the adult human hippocampus, the homeostasis and developmental potentials of neural stem cells (NSCs) under different contexts remain unclear. Based on our generated s…
View article: Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea
Preclinical evaluation of the safety and effectiveness of a new bioartificial cornea Open
Cross-linking agents are frequently used to restore corneal properties after decellularization, and it is especially important to select an appropriate method to avoid excessive cross-linking. In addition, how to promote wound healing and …
View article: Orbital Exenteration and Reconstruction Using a Free Radial Forearm Flap in Conjunctival Melanoma: Old but Gold
Orbital Exenteration and Reconstruction Using a Free Radial Forearm Flap in Conjunctival Melanoma: Old but Gold Open
Conjunctival melanoma is a rare and potentially deadly tumor. Therefore, adequate oncological resection is essential, commonly leading to total orbital exenteration, which causes patients' extensive functional and cosmetic impairment. As a…
View article: Genome editing of pseudorabies virus in the CRISPR/Cas9 era: a mini-review
Genome editing of pseudorabies virus in the CRISPR/Cas9 era: a mini-review Open
Pseudorabies virus (PRV) is an important swine virus that has a significant impact on the global swine industry. PRV is a member of the herpesvirus family, specifically the alphaherpesvirus subfamily, and has been extensively utilized as a…