Juan Carlos Rodrı́guez
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View article: Clinical Impact of Implementing a Specific Clinical Pathway for the Management of Clostridioides difficile Infection
Clinical Impact of Implementing a Specific Clinical Pathway for the Management of Clostridioides difficile Infection Open
ClinicalTrials.gov identifier NCT04801862.
View article: Multicenter evaluation of the QuickMIC® rapid AST system in clinical practice: impact on turnaround time compared to routine AST systems
Multicenter evaluation of the QuickMIC® rapid AST system in clinical practice: impact on turnaround time compared to routine AST systems Open
Increased antibiotic resistance highlights the need for new, rapid antibiotic susceptibility tests to guide therapy, especially in critical disease such as bloodstream infections and sepsis. This study investigates a new ultra-rapid AST sy…
View article: Efficacy and safety of dexamethasone compared to placebo in patients with severe influenza infection. (FLUDEX study): a study protocol for a randomised controlled trial in Spain
Efficacy and safety of dexamethasone compared to placebo in patients with severe influenza infection. (FLUDEX study): a study protocol for a randomised controlled trial in Spain Open
Introduction The combination with corticosteroids as immunomodulators has been the subject of debate in different infectious syndromes. The main objective of this study is to evaluate the efficacy (the percentage of patients hospitalised w…
View article: Impact of the initial administration of an antiretroviral drug with latency reversal properties on the HIV reservoir size
Impact of the initial administration of an antiretroviral drug with latency reversal properties on the HIV reservoir size Open
The elimination of the latent viral reservoir remains the main barrier in the quest for a cure for people with HIV (PWH). The administration of latency reversal agents (LRA) at antiretroviral treatment (ART) initiation could improve the ef…
View article: Detección de Salmonella spp. y enterobacterias en huevo para consumo proveniente de sistemas libres de jaula
Detección de Salmonella spp. y enterobacterias en huevo para consumo proveniente de sistemas libres de jaula Open
Se estudió la presencia de Salmonella spp. y el recuento de Enterobacterias en huevos de gallinas alojadas en sistemas libres de jaula en 30 granjas de la provincia de Buenos Aires y sur de Santa Fe. Los análisis realizados con el fin de d…
View article: In-Vitro Cytotoxicity and Biological Potential of Mn-Doped Ag₂S Nanoparticles in Breast Cancer Cell Lines
In-Vitro Cytotoxicity and Biological Potential of Mn-Doped Ag₂S Nanoparticles in Breast Cancer Cell Lines Open
The integration of manganese (Mn) into silver sulfide (Ag₂S) nanoparticles offers a promising avenue for enhancing their physicochemical properties and biological activity for breast cancer applications. This study investigates the synthes…
View article: Effectiveness of immunization strategies for preventing severe acute respiratory infection during the 2023/2024 season in a Spanish health department
Effectiveness of immunization strategies for preventing severe acute respiratory infection during the 2023/2024 season in a Spanish health department Open
The observed EIS was likely due to RSV immunization in infants' high coverage with good effectiveness and low influenza B circulation.
View article: Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020
Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020 Open
View article: Effectiveness of immunization strategies for preventing severe acute respiratory infection during the 2023/2024 season in a Spanish health department
Effectiveness of immunization strategies for preventing severe acute respiratory infection during the 2023/2024 season in a Spanish health department Open
View article: Effectiveness of oral step-down therapy and early oral switch for bloodstream infections caused by Enterobacterales: A post hoc emulation trial of the SIMPLIFY trial
Effectiveness of oral step-down therapy and early oral switch for bloodstream infections caused by Enterobacterales: A post hoc emulation trial of the SIMPLIFY trial Open
View article: Author Correction: The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain
Author Correction: The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain Open
View article: Effects of Ozone and Biological Degradation on the Removal and Transformation of Highly Hydrophilic DOC in a Conventional Water Treatment Process
Effects of Ozone and Biological Degradation on the Removal and Transformation of Highly Hydrophilic DOC in a Conventional Water Treatment Process Open
View article: In‐Hospital Death and Risk Factors in Adults With Influenza in Spain (2016–2022): A Cross‐Sectional Study With Focus on Older Patients
In‐Hospital Death and Risk Factors in Adults With Influenza in Spain (2016–2022): A Cross‐Sectional Study With Focus on Older Patients Open
Background and Aims Influenza mortality rates varying across different populations. This study aims to assess influenza lethality in hospitalized adults (≥ 15 years) and identify key risk factors according to age. Methods We designed a ret…
View article: A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021)
A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021) Open
Objectives The study aimed to analyze in-hospital mortality (IHM) among all COVID-19 patients hospitalized in Spain between March 1, 2020, and December 31, 2021, and to compare two distinct periods: the prevaccination period (March 1, 2020…
View article: Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studies
Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studies Open
View article: The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document
The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document Open
View article: Long-term effectiveness and tolerability of dolutegravir/lamivudine in treatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks
Long-term effectiveness and tolerability of dolutegravir/lamivudine in treatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks Open
Objectives To evaluate the long-term effectiveness, persistence and tolerability of dolutegravir (DTG)/lamivudine (3TC), compared with the most frequently prescribed first-line treatment regimens, among antiretroviral-naive people with HIV…
View article: Double sticker over knife to assess myotomy and mucosectomy length during Zenker’s peroral endoscopic myotomy for Zenker’s diverticulum
Double sticker over knife to assess myotomy and mucosectomy length during Zenker’s peroral endoscopic myotomy for Zenker’s diverticulum Open
View article: Comparison of Precision, Agreement, and Accuracy of Two Swept-Source Optical Coherence Tomography Biometers
Comparison of Precision, Agreement, and Accuracy of Two Swept-Source Optical Coherence Tomography Biometers Open
Background/Objectives: This study’s aim was to compare the precision, agreement, and accuracy in axial length (AL) measurements of Argos® (Alcon Healthcare, US) and Eyestar 900® (Haag-Streit, Switzerland) swept-source optical coherence tom…
View article: Identification of Antimicrobial-Resistant Zoonotic Bacteria in Swine Production: Implications from the One Health Perspective
Identification of Antimicrobial-Resistant Zoonotic Bacteria in Swine Production: Implications from the One Health Perspective Open
Antimicrobial resistance poses a major threat to global health and food security and is primarily driven by antimicrobial use in human and veterinary medicine. Understanding its epidemiology at farm level is crucial for effective control m…
View article: Valproic acid could help in the fight against COVID-19: A case–control study
Valproic acid could help in the fight against COVID-19: A case–control study Open
Patients with VPA within the therapeutic range had a reduction of SARS-Cov-2 infection incidence greater than 75%. There is a downward trend in the risk of COVID-19 admission by SARS-CoV-2 in patients on VPA therapy. These findings warrant…
View article: Evaluation of the quickmic system in the rapid diagnosis of Gram-negative bacilli bacteremia
Evaluation of the quickmic system in the rapid diagnosis of Gram-negative bacilli bacteremia Open
Rapid microbiological diagnosis of the antibiotic susceptibility of Gram-negative bacilli is a priority in clinical microbiology, especially in cases of bacteremia. The rapid advancement of antimicrobial resistance proposes a challenge for…
View article: Genomic Analysis of Antimicrobial Resistance in Pseudomonas aeruginosa from a “One Health” Perspective
Genomic Analysis of Antimicrobial Resistance in Pseudomonas aeruginosa from a “One Health” Perspective Open
The “One Health” approach provides a comprehensive framework for understanding antimicrobial resistance. This perspective is of particular importance in the study of Pseudomonas aeruginosa, as it is not only a pathogen that affects humans …
View article: Are SARS-CoV-2 antigen tests useful in routine emergency department care?
Are SARS-CoV-2 antigen tests useful in routine emergency department care? Open
View article: Comparison of Different Methods for Assaying the In Vitro Activity of Cefiderocol against Carbapenem-Resistant Pseudomonas aeruginosa Strains: Influence of Bacterial Inoculum
Comparison of Different Methods for Assaying the In Vitro Activity of Cefiderocol against Carbapenem-Resistant Pseudomonas aeruginosa Strains: Influence of Bacterial Inoculum Open
Carbapenem-resistant Pseudomonas aeruginosa infections represent a critical public health concern, highlighting the need for the development of effective antibiotics. Cefiderocol demonstrated potent in vitro activity against Pseudomonas ae…
View article: Swine farm environmental microbiome: exploring microbial ecology and functionality across farms with high and low sanitary status
Swine farm environmental microbiome: exploring microbial ecology and functionality across farms with high and low sanitary status Open
Introduction Stringent regulations in pig farming, such as antibiotic control and the ban on certain additives and disinfectants, complicate disease control efforts. Despite the evolution of microbial communities inside the house environme…
View article: Impact of influenza related hospitalization in Spain: characteristics and risk factor of mortality during five influenza seasons (2016 to 2021)
Impact of influenza related hospitalization in Spain: characteristics and risk factor of mortality during five influenza seasons (2016 to 2021) Open
Background Estimating the global influenza burden in terms of hospitalization and death is important for optimizing prevention policies. Identifying risk factors for mortality allows for the design of strategies tailored to groups at the h…
View article: Service-learning to improve training, knowledge transfer, and awareness in forest fire management
Service-learning to improve training, knowledge transfer, and awareness in forest fire management Open
View article: [Positioning proposal on the recommendations for the use of masks in health centers after the cessation of the mandatory use in Spain].
[Positioning proposal on the recommendations for the use of masks in health centers after the cessation of the mandatory use in Spain]. Open
Since the beginning of the COVID-19 pandemic in March 2020, the use of masks has been a fundamental pillar for controlling the transmission of SARS-CoV-2 in different areas. Its mandatory nature has been regulated by different regulations,…
View article: Different Transmission Patterns between Third Generation Cephalosporin and Carbapenem Resistance in Klebsiella Pneumoniae
Different Transmission Patterns between Third Generation Cephalosporin and Carbapenem Resistance in Klebsiella Pneumoniae Open