Explanipedia

Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7 Open

Zhichao Wu, Srinivas R. Sadda, Thomas Ach, Barbara A. Blodi, Ferdinando Bottoni , et al. · 2025

Prediction for 2-Year Vision Outcomes Using Early Morphologic and Functional Responses in the Comparison of Age-related Macular Degeneration Treatments Trials Open

Katie Xue, Peiying Hua, Maureen G. Maguire, Ebenezer Daniel, Glenn J. Jaffe , et al. · 2023

Thiazolidinedione use and retinal fluid in the comparison of age-related macular degeneration treatments trials Open

Jason Q. Core, Peiying Hua, Ebenezer Daniel, Juan E. Grunwald, Glenn J. Jaffe , et al. · 2022

Background Thiazolidinediones, commonly used antidiabetic medications, have been associated with an increased risk of development of diabetic macular oedema and increased vascular endothelial cell permeability. Macular neovascularisation i…

Predominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials Open

Jason Q. Core, Maxwell Pistilli, Peiying Hua, Ebenezer Daniel, Juan E. Grunwald , et al. · 2022

Predominantly Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials Open

Jason Q. Core, Maxwell Pistilli, Ebenezer Daniel, Juan E. Grunwald, Cynthia A. Toth , et al. · 2021

SYSTEMIC MEDICATION USE AND THE INCIDENCE AND GROWTH OF GEOGRAPHIC ATROPHY IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS Open

Delu Song, Peiying Hua, Brian L. VanderBeek, Joshua L. Dunaief, Juan E. Grunwald , et al. · 2020

Purpose: To determine associations of systemic medications with the incidence and growth of geographic atrophy (GA) in participants of the comparison of age-related macular degeneration treatments trials. Methods: Participants of compariso…

Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials Open

Avni P. Finn, Maxwell Pistilli, Vincent Tai, Ebenezer Daniel, Gui‐Shuang Ying , et al. · 2020

Progression of retinopathy and incidence of cardiovascular disease: findings from the Chronic Renal Insufficiency Cohort Study Open

Juan E. Grunwald, Maxwell Pistilli, Gui‐Shuang Ying, Maureen G. Maguire, Ebenezer Daniel , et al. · 2020

Purpose Chronic kidney disease (CKD) patients often develop cardiovascular disease (CVD) and retinopathy. The purpose of this study was to assess the association between progression of retinopathy and concurrent incidence of CVD events in …

BETA-PERIPAPILLARY ATROPHY AND GEOGRAPHIC ATROPHY IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS Open

Anton M. Kolomeyer, Eli Smith, Ebenezer Daniel, Gui‐Shuang Ying, Wei Pan , et al. · 2020

Purpose: To determine associations between beta-peripapillary atrophy (B-PPA) and incidence and growth of geographic atrophy (GA) in eyes treated with anti–vascular endothelial growth factor agents in the Comparison of Age-Related Macular …

Orally Administered Alpha Lipoic Acid as a Treatment for Geographic Atrophy Open

Benjamin J. Kim, Allan A. Hunter, Alexander J. Brucker, Paul Hahn, Karen M. Gehrs , et al. · 2020

Incidence and Progression of Nongeographic Atrophy in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Clinical Trial Open

Ebenezer Daniel, Maureen G. Maguire, Juan E. Grunwald, Cynthia A. Toth, Glenn J. Jaffe , et al. · 2020

ClinicalTrials.gov Identifier: NCT00593450.

Characteristics of Eyes With Good Visual Acuity at 5 Years After Initiation of Treatment for Age-Related Macular Degeneration but Not Receiving Treatment From Years 3 to 5 Open

Drew Scoles, Gui‐Shuang Ying, Wei Pan, Peiying Hua, Juan E. Grunwald , et al. · 2020

ClinicalTrials.gov Identifier: NCT00593450.

Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration Open

Robyn H. Guymer, Philip J. Rosenfeld, Christine A. Curcio, Frank G. Holz, Giovanni Staurenghi , et al. · 2019

Association Between Cilioretinal Arteries and Advanced Age-Related Macular Degeneration Open

J. Clay Bavinger, Gui‐Shuang Ying, Ebenezer Daniel, Juan E. Grunwald, Maureen G. Maguire · 2019

ClinicalTrials.gov identifier: NCT00593450.

Incidence and Features of Geographic Atrophy in Fellow Eyes in the Comparison of Age-related Macular Degeneration Treatment Trials (CATT) Open

Delu Song, Gui‐Shuang Ying, Juan E. Grunwald, Ebenezer Daniel, Maureen G. Maguire , et al. · 2019

Association Between Progression of Retinopathy and Concurrent Progression of Kidney Disease Open

Juan E. Grunwald, Maxwell Pistilli, Gui‐Shuang Ying, Ebenezer Daniel, Maureen G. Maguire , et al. · 2019

Progression of retinopathy appears to be associated with progression of CKD on univariable analysis but not on multivariable analysis suggesting that similar risk factors may be affecting the progression of both retinal and chronic kidney …

Distribution of OCT Features within Areas of Macular Atrophy or Scar after 2 Years of Anti-VEGF Treatment for Neovascular AMD in CATT Open

Cynthia A. Toth, Vincent Tai, Maxwell Pistilli, Stephanie J. Chiu, Katrina Winter , et al. · 2018

Five-Year Follow-up of Nonfibrotic Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials Open

Ebenezer Daniel, Gui‐Shuang Ying, Benjamin J. Kim, Cynthia A. Toth, Frederick L. Ferris , et al. · 2018

Macular Morphology and Visual Acuity in Year Five of the Comparison of Age-related Macular Degeneration Treatments Trials Open

Glenn J. Jaffe, Gui‐Shuang Ying, Cynthia A. Toth, Ebenezer Daniel, Juan E. Grunwald , et al. · 2018

ASSOCIATION BETWEEN ORAL IRON SUPPLEMENTATION AND RETINAL OR SUBRETINAL HEMORRHAGE IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENT TRIALS Open

Delu Song, Gui‐Shuang Ying, Joshua L. Dunaief, Rupak Bhuyan, Yafeng Li , et al. · 2018

Purpose: Because patients often take iron supplements without medical indication, and iron can accumulate in vascular endothelial cells, the authors evaluated the association of oral iron supplementation with retinal/subretinal hemorrhage …

Association between Oral Iron Supplementation and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials Open

Delu Song, Gui‐Shuang Ying, Joshua L. Dunaief, Rupak Bhuyan, Yafeng Li , et al. · 2018

Association of Pulse Wave Velocity With Chronic Kidney Disease Progression and Mortality Open

Raymond R. Townsend, Amanda H. Anderson, Julio A. Chirinos, Harold I. Feldman, Juan E. Grunwald , et al. · 2018

Patients with chronic kidney diseases (CKDs) are at risk for further loss of kidney function and death, which occur despite reasonable blood pressure treatment. To determine whether arterial stiffness influences CKD progression and death, …

Development and Course of Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials Open

Ebenezer Daniel, Wei Pan, Gui‐Shuang Ying, Benjamin J. Kim, Juan E. Grunwald , et al. · 2018

Baseline Predictors for Five-Year Visual Acuity Outcomes in the Comparison of AMD Treatment Trials Open

Gui‐Shuang Ying, Maureen G. Maguire, Wei Pan, Juan E. Grunwald, Ebenezer Daniel , et al. · 2017

Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT Open

Srinivas R. Sadda, Robyn H. Guymer, Frank G. Holz, Steffen Schmitz-Valckenberg, Christine A. Curcio , et al. · 2017

Linking optical coherence tomographic, angiographic and photographic lesion components in neovascular age-related macular degeneration in the Comparison of Age-related Macular Degeneration Treatments Trials Open

Vincent Tai, Stephanie J. Chiu, Katrina Winter, Ebenezer Daniel, Juan E. Grunwald , et al. · 2017

Baseline Predictors of Five-Year Visual Acuity in the Comparison of AMD Treatment Trials (CATT) Open

Gui‐Shuang Ying, Maureen G. Maguire, Wei Pan, Juan E. Grunwald, Ebenezer Daniel , et al. · 2017

Incidence and risk factors for neovascular AMD in the fellow eye in the Comparison of AMD Treatment Trials (CATT) Follow-up Study Open

Maureen G. Maguire, Wei Pan, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe , et al. · 2017

Distribution of optical coherence tomographic morphologic components within areas appearing as atrophic or scarred after two years of anti-VEGF treatment for neovascular age-related macular degeneration in the Comparison of Age-related Macular Degeneration Treatments Trials Open

Cynthia A. Toth, Vincent Tai, Maxwell Pistilli, Stephanie J. Chiu, Katrina Winter , et al. · 2017

Association between pseudodrusen and delayed patchy choroidal filling in the comparison of age‐related macular degeneration treatments trials Open

Qiang Zhou, Ebenezer Daniel, Juan E. Grunwald, Maureen G. Maguire, Dina Y. Gewaily , et al. · 2017

Pseudodrusen have been identified as a strong risk factor for development of late age-related macular degeneration (AMD; Alten & Eter 2015; Chang et al. 2016; Zhou et al. 2016) and macular atrophy (Munk et al. 2016). However, the pathophys…

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