Lijuan Zhu
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View article: Itaconate-functionalized tetrahedral framework nucleic acids break the dry eye vicious cycle through dual antioxidant and anti-inflammatory actions
Itaconate-functionalized tetrahedral framework nucleic acids break the dry eye vicious cycle through dual antioxidant and anti-inflammatory actions Open
Dry eye disease (DED) is a prevalent ocular surface disorder characterized by chronic inflammation and oxidative stress, significantly impacting vision and quality of life. Although reactive oxygen species (ROS) serve as a key upstream reg…
View article: Protein disulfide isomerases regulate androgen receptor stability and promote prostate cancer cell growth and survival
Protein disulfide isomerases regulate androgen receptor stability and promote prostate cancer cell growth and survival Open
Cancer cells exhibit accelerated protein production to accommodate their high rates of growth and proliferation. Elevated protein synthesis creates a dependency on endoplasmic reticulum (ER)-resident proteins and chaperones, which are requ…
View article: PbrNAC34a- PbrMYB3/65- PbrACO2 cascade plays a role in citrate difference between the pericarp and cortex tissues of pear (P. bretschneideri Rehd.) fruit
PbrNAC34a- PbrMYB3/65- PbrACO2 cascade plays a role in citrate difference between the pericarp and cortex tissues of pear (P. bretschneideri Rehd.) fruit Open
Citrate is critical to the flavor of horticultural fruit and governed by ACO. However, the specific ACO and its upstream regulators involved in citrate metabolism during pear ( Pyrus spp.) fruit development remained uncharacterized. This s…
View article: Unraveling the Effect of Retained Austenite on the Very High Cycle Fatigue Crack Initiation Mechanism of Carbide‐Free Bainitic Steel
Unraveling the Effect of Retained Austenite on the Very High Cycle Fatigue Crack Initiation Mechanism of Carbide‐Free Bainitic Steel Open
The very high cycle fatigue behaviors of a carbide‐free bainitic steel were investigated to unravel the mechanisms of two types of non‐inclusion induced crack initiation characteristic areas with different morphologies and to explore the r…
View article: Deep learning image reconstruction and adaptive statistical iterative reconstruction on coronary artery calcium scoring in high risk population for coronary heart disease
Deep learning image reconstruction and adaptive statistical iterative reconstruction on coronary artery calcium scoring in high risk population for coronary heart disease Open
View article: A Biodegradable 2D Metallic MoS<sub>2</sub> Genesheet for Synergistic NIR‐II Photothermal Immunotherapy
A Biodegradable 2D Metallic MoS<sub>2</sub> Genesheet for Synergistic NIR‐II Photothermal Immunotherapy Open
Developing promising biodegradable second near‐infrared (NIR‐II) immune agonists to overcome the insufficient immunogenicity of tumor cells and the poor immune response remains challenging. In this work, a biodegradable “2D genesheet” is e…
View article: The effect of sulphur-bearing ash on the high-temperature corrosion in CO2–H2O gas for Fe–9Cr alloy with FeCoCrNi high-entropy alloys coating fabricated via selective laser melting
The effect of sulphur-bearing ash on the high-temperature corrosion in CO2–H2O gas for Fe–9Cr alloy with FeCoCrNi high-entropy alloys coating fabricated via selective laser melting Open
In oxyfuel combustion, CO2–H2O gas is highly corrosive to the furnace tubes materials in power plants. Sulphur is a general impurity in oxyfuel combustion, and its presence in ash deposit has altered the high temperature corrosion of Fe–Cr…
View article: Preparation and Properties of <scp>3D</scp>‐Printed Hydrogel‐Embedded <scp>PLA</scp> Composite Scaffolds
Preparation and Properties of <span>3D</span>‐Printed Hydrogel‐Embedded <span>PLA</span> Composite Scaffolds Open
This study presents the development of a biodegradable composite scaffold designed to address the limitations associated with conventional bone repair materials. 3D‐printing filaments were developed using fish scale powder (FSP) or fish sc…
View article: GalNAc End‐Capped Poly(β‐amino ester)s with Screened Side Chains for Efficient Gene Delivery
GalNAc End‐Capped Poly(β‐amino ester)s with Screened Side Chains for Efficient Gene Delivery Open
Plasmids are widely used gene vectors in gene therapy, yet their efficient delivery remains a major challenge for achieving optimal therapeutic outcomes. Recently, poly(β‐amino esters) (PBAEs) have emerged as promising carriers for non‐vir…
View article: Antimicrobial peptide AMP-17 induces protection against systemic candidiasis and interacts synergistically with fluconazole against Candida albicans biofilm
Antimicrobial peptide AMP-17 induces protection against systemic candidiasis and interacts synergistically with fluconazole against Candida albicans biofilm Open
Candida albicans , a common commensal and opportunistic fungal pathogen in humans, can occasionally progress to disseminated candidiasis which is a serious condition with a high morbidity and fatality rate. The emergence of drug-resistant …
View article: Mechanistic role of vanadium microalloying in improving corrosion resistance of low carbon bainitic steel
Mechanistic role of vanadium microalloying in improving corrosion resistance of low carbon bainitic steel Open
We here investigated the effect of vanadium microalloying on the microstructure, mechanical properties, especially corrosion performances of low carbon bainitic steels. The corrosion behaviors of the steels with different vanadium contents…
View article: The effect of social isolation on the cognitive ability of the oldest old in Chinese nursing homes in post-COVID-19: a moderated chain mediation model
The effect of social isolation on the cognitive ability of the oldest old in Chinese nursing homes in post-COVID-19: a moderated chain mediation model Open
Background Both pre-or post-COVID-19, older adults residing in nursing homes are at significant risk for social isolation, which is negatively associated with cognitive ability. Currently, the elderly aged 80 years and older are the fastes…
View article: Intrinsic capacity loss rates and protective factors among individuals aged 80 years and older in Chinese nursing homes: A latent class analysis
Intrinsic capacity loss rates and protective factors among individuals aged 80 years and older in Chinese nursing homes: A latent class analysis Open
Prior to this cross-sectional study, the intrinsic capacity (IC) loss rates and protective factors in nursing homes for individuals aged 80 and older remained unexplored. Analysing 434 participants, this study found 86.9 % of individuals e…
View article: Development and preliminary validation of a questionnaire on the care needs of family carers of older individuals with disabilities in China: a mixed methods study
Development and preliminary validation of a questionnaire on the care needs of family carers of older individuals with disabilities in China: a mixed methods study Open
View article: Palladium-catalyzed Suzuki-Miyaura cross-couplings of stable glycal boronates for robust synthesis of C-1 glycals
Palladium-catalyzed Suzuki-Miyaura cross-couplings of stable glycal boronates for robust synthesis of C-1 glycals Open
C- 1 Glycals serve as pivotal intermediates in synthesizing diverse C -glycosyl compounds and natural products, necessitating the development of concise, efficient and user-friendly methods to obtain C- 1 glycosides is essential. The Suzuk…
View article: Microbial adaption to stoichiometric imbalances regulated the size of soil mineral-associated organic carbon pool under continuous organic amendments
Microbial adaption to stoichiometric imbalances regulated the size of soil mineral-associated organic carbon pool under continuous organic amendments Open
Soil microorganisms play a key role in regulating soil organic carbon (SOC) accrual. Organic amendments with distinct stoichiometry may lead to imbalanced supply of carbon (C), nitrogen (N), and phosphorus (P) to the microbiome, causing ch…
View article: PbrWRKY62-PbrADC1 module involves in superficial scald development of Pyrus bretschneideri Rehd.fruit via regulating putrescine biosynthesis
PbrWRKY62-PbrADC1 module involves in superficial scald development of Pyrus bretschneideri Rehd.fruit via regulating putrescine biosynthesis Open
Putrescine plays a role in superficial scald development during the cold storage of pear fruit. However, the molecular mechanism behind this phenomenon has not been un-fully clarified until recently. In this study, a conjoint analysis of m…
View article: CSPP1 stabilizes microtubules by capping both plus and minus ends
CSPP1 stabilizes microtubules by capping both plus and minus ends Open
Although the dynamic instability of microtubules (MTs) is fundamental to many cellular functions, quiescent MTs with unattached free distal ends are commonly present and play important roles in various events to power cellular dynamics. Ho…
View article: Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty
Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty Open
BACKGROUND With the continuous growth of the modern elderly population, the risk of fracture increases. Hip fracture is a common type of fracture in older people. Total hip arthroplasty (THA) has significant advantages in relieving chronic…
View article: Fracture Failure Analysis of a 5-7/8” Drill Pipe Pin Joint in an Ultra-deep Gas Well
Fracture Failure Analysis of a 5-7/8” Drill Pipe Pin Joint in an Ultra-deep Gas Well Open
In recent years, the frequency of drill pipe failure accidents has increased during ultra-deep well drilling process. The fracture failure of pin joint of a 5-7/8” drill pipe happened in an ultra-deep gas well after thirty-five hours’ serv…
View article: Polymer Composite Thermoforming: Ultrasonic-Assisted Optimization for Enhanced Adhesive Performance in Automotive Interior Components
Polymer Composite Thermoforming: Ultrasonic-Assisted Optimization for Enhanced Adhesive Performance in Automotive Interior Components Open
Dual-component epoxy resins are widely used for bonding different materials in automotive interior processing. However, due to the complexity and variability of automotive interior parts, uneven temperature distribution on curved surfaces …
View article: The Characteristics of Refractory Steel and Its Development and Application in Petroleum and Other Fields
The Characteristics of Refractory Steel and Its Development and Application in Petroleum and Other Fields Open
Because the strength of structural steel decreases sharply at high temperature, it must be sprayed with fire-resistant coating or fire-resistant materials for composite use. The strength of refractory steel can be reduced by no more than 1…
View article: Research on Traditional Image Segmentation Method Based on Oil Drilling Pipe Defects
Research on Traditional Image Segmentation Method Based on Oil Drilling Pipe Defects Open
This study explores the feasibility and efficacy of conventional image seg-mentation technology in diagnosing failures in oil drilling pipe images. Simultaneously, it envisions an intelligent approach to diagnose defects in oil drilling pi…
View article: Research on Failure Cause and Mechanism of High Temperature Protective Coatings
Research on Failure Cause and Mechanism of High Temperature Protective Coatings Open
In the aerospace industry, engines are exposed to extreme stress during long-term operation in high-temperature oxidation atmospheres and gas-corrosive environments. To extend the engine’s service life, it is often necessary to apply high-…
View article: The erosion-corrosion behaviors of the full-scale Ni-P and Ni-Cu-NiW internal coating tubing
The erosion-corrosion behaviors of the full-scale Ni-P and Ni-Cu-NiW internal coating tubing Open
In the present work, a self-built device called the “full scale tubular goods erosion-corrosion test system” was used to investigate the erosion-corrosion behavior of Ni-P and Ni-Cu-NiW internal coating tubing in a simulated operating cond…
View article: Fracture failure analysis of the main shaft of a large sewage treatment equipment
Fracture failure analysis of the main shaft of a large sewage treatment equipment Open
In view of the main shaft fracture failure accident occurred in the service process of a sewage treatment equipment, this paper carried out the fracture macro analysis, chemical composition analysis, material mechanical properties testing,…
View article: Fracture failure of internal thread joint on back redressing stabilizer
Fracture failure of internal thread joint on back redressing stabilizer Open
Stabilizers have been one of the most critical components in the drilling string, due to their great function to prevent the unintentional sidetracking and vibrations in whole drilling assembly. In recent years, with the increasing of the …
View article: Performance Research of Natural Mica Modified with Zirconium-Based Metal–Organic Frameworks for an Epoxy Resin Anti-Corrosion Coating
Performance Research of Natural Mica Modified with Zirconium-Based Metal–Organic Frameworks for an Epoxy Resin Anti-Corrosion Coating Open
A new composite material made from mica and a metal–organic framework (MOF) has been developed to improve the anticorrosive capabilities of epoxy resin coatings. The layered mica was loaded with denser and more uniform UIO-66 nanoparticles…
View article: Development and Preliminary Validation of Questionnaire on Care Needs of Family Caregivers of Disabled Elderly People in China:a mixed methods study
Development and Preliminary Validation of Questionnaire on Care Needs of Family Caregivers of Disabled Elderly People in China:a mixed methods study Open
Background Ensuring the wellness of disabled elderly individuals requires prioritizing the care needs of their caregivers. However, current practice lacks validated tools to measure the needs of caregivers in a home environment. Thus, this…
View article: A High−Performance Anti−Corrosive Epoxy Coating Based on Ultra−Thin Hydroxyapatite Nanosheets with pH−Responsive Functions
A High−Performance Anti−Corrosive Epoxy Coating Based on Ultra−Thin Hydroxyapatite Nanosheets with pH−Responsive Functions Open
The changes in the working environment have necessitated greater requirements in terms of the long−term anti−corrosion ability of metal anti−corrosion coatings, and the emergence of intelligent coatings has met this demand. A nanocontainer…