Juan M. Guerrero
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View article: Cell-Free DNA Levels During the First Hours After Liver Transplantation: A Key Biomarker for Patient Survival and Outcomes
Cell-Free DNA Levels During the First Hours After Liver Transplantation: A Key Biomarker for Patient Survival and Outcomes Open
(1) Background: We propose that cfDNA levels may serve as a valuable biomarker for monitoring the progress of liver transplant recipients, reflecting the quality of the donated organ, and predicting patient prognosis and survival. Thus, we…
View article: Reconstruction Using Pedicled Inguinal Flap Type Mc Gregor in the Right Hand First Digit, Secondary to Necrosis Due to Loxosceles Spider Bite: Case Report
Reconstruction Using Pedicled Inguinal Flap Type Mc Gregor in the Right Hand First Digit, Secondary to Necrosis Due to Loxosceles Spider Bite: Case Report Open
Loxosceles spider bite represents a relevant health problem in endemic regions, mainly due to its cutaneous manifestations characterized by progressive necrosis that is difficult to manage. We present the case of a 13-year-old female patie…
View article: Epiphrenic Diverticulum and Zenker's Diverticulum: Simultaneous Double Surgical Approach: Case Report
Epiphrenic Diverticulum and Zenker's Diverticulum: Simultaneous Double Surgical Approach: Case Report Open
Esophageal diverticula are a rare condition, with an incidence of 0.06 to 4% and can present as pharyngoesophageal (Zenker), mid-esophageal (epibronchial), and/or distal diverticula, the latter also called epiphrenic, representing 15% of a…
View article: Impacto de un programa propioceptivo en el equilibrio dinámico y la prevención de lesiones de tobillo en jugadores profesionales de baloncesto
Impacto de un programa propioceptivo en el equilibrio dinámico y la prevención de lesiones de tobillo en jugadores profesionales de baloncesto Open
Las lesiones de tobillo representan hasta el 45% de todas las lesiones en jugadores de baloncesto, siendo una de las causas más comunes de ausentismo deportivo. En este contexto, el presente estudio tuvo como objetivo evaluar el impacto de…
View article: Pleural Fluid Biomarkers of Pediatric Parapneumonic Effusion
Pleural Fluid Biomarkers of Pediatric Parapneumonic Effusion Open
Background/Objectives: Parapneumonic pleural effusion (PPE) secondary to community-acquired pneumonia is the most common cause of pediatric pleural effusion. This study aimed to evaluate the pleural fluid characteristics of pediatric patie…
View article: Quality of life and clinical data in hemodialysis patients with different degrees of pruritus
Quality of life and clinical data in hemodialysis patients with different degrees of pruritus Open
Chronic kidney disease-associated pruritus (CKD-aP), a persistent itching sensation, is prevalent among hemodialysis patients. This study aims to understand its prevalence, its possible association with selected solutes, and impact on qual…
View article: Características y desenlaces de los pacientes ventilados por neumonía por SARS-CoV-2 en un hospital chileno
Características y desenlaces de los pacientes ventilados por neumonía por SARS-CoV-2 en un hospital chileno Open
Características y desenlaces de los pacientes ventilados por neumonía por SARS-CoV-2 en un hospital chileno
View article: Donor-Specific Cell-Free DNA qPCR Quantification as a Noninvasive Accurate Biomarker for Early Rejection Detection in Liver Transplantation
Donor-Specific Cell-Free DNA qPCR Quantification as a Noninvasive Accurate Biomarker for Early Rejection Detection in Liver Transplantation Open
(1) Background: Graft-cell-free DNA (cfDNA) in the circulation of liver transplant recipients has been proposed as a noninvasive biomarker of organ rejection. The aim of this study was to detect donor-specific cfDNA (ds-cfDNA) in the recip…
View article: GPX3 Overexpression in Cumulus Cells Entails a Poor Prognosis for Uterine Implantation of Morphotype A Embryos
GPX3 Overexpression in Cumulus Cells Entails a Poor Prognosis for Uterine Implantation of Morphotype A Embryos Open
Morphological embryo quality is an accurate prognostic tool for the success of assisted reproduction implantation, although complete certainty cannot be guaranteed. The transcriptome of the cumulus cells could be monitored as a faithful re…
View article: Production, quality and profitability of three ecotypes of aguaymanto (Physalis peruviana L.)
Production, quality and profitability of three ecotypes of aguaymanto (Physalis peruviana L.) Open
El aguaymanto (Physalis peruviana) es un cultivo alternativo, debido a que posee gran diversidad genética, con demanda creciente en los mercados nacional e internacional; pero, el insipiente conocimiento de ecotipos es una gran limitante. …
View article: Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE−/− Mice
Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE−/− Mice Open
Metabolic-associated fatty liver disease (MAFLD) is the most important cause of liver disease worldwide. It is characterized by the accumulation of fat in the liver and is closely associated with abdominal obesity. In addition, oxidative s…
View article: Genotype–phenotype correlation of 17 cases of Pompe disease in Spanish patients and identification of 4 novel GAA variants
Genotype–phenotype correlation of 17 cases of Pompe disease in Spanish patients and identification of 4 novel GAA variants Open
View article: Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial)
Safety and Efficacy of a Beverage Containing Lupine Protein Hydrolysates on the Immune, Oxidative and Lipid Status in Healthy Subjects: An Intervention Study (the Lupine‐1 Trial) Open
Scope We have previously demonstrated the anti‐inflammatory and antioxidant properties of in vitro administered Lupinus angustifolius protein hydrolysates (LPHs) on human peripheral blood mononuclear cells (PBMCs). This study aims to evalu…
View article: Rapid decline of anti-SARS-CoV-2 antibodies in patients on haemodialysis: the COVID-FRIAT study
Rapid decline of anti-SARS-CoV-2 antibodies in patients on haemodialysis: the COVID-FRIAT study Open
Background Coronavirus disease 2019 (COVID-19) patients on haemodialysis (HD) have high mortality. We investigated the value of reverse transcription polymerase chain reaction (RT-PCR) and the dynamic changes of antibodies (enzyme-linked i…
View article: Author response for "Accuracy diagnosis improvement of Fabry disease from dried blood spots: enzyme activity, lyso-Gb3 accumulation and GLA gene sequencing"
Author response for "Accuracy diagnosis improvement of Fabry disease from dried blood spots: enzyme activity, lyso-Gb3 accumulation and GLA gene sequencing" Open
View article: Data regarding: Melatonin induces neuroprotection in experimental autoimmune encephalomyelitis by impairing T cell priming and reactivation in the central nervous system
Data regarding: Melatonin induces neuroprotection in experimental autoimmune encephalomyelitis by impairing T cell priming and reactivation in the central nervous system Open
Experimental autoimmune encephalomyelitis (EAE), the pre-clinical animal model of human multiple sclerosis, is triggered by myelin-specific T effector cells that are primed in peripheral lymph nodes and migrate to the central nervous syste…
View article: Author response for "Accuracy diagnosis improvement of Fabry disease from dried blood spots: enzyme activity, lyso-Gb3 accumulation and GLA gene sequencing"
Author response for "Accuracy diagnosis improvement of Fabry disease from dried blood spots: enzyme activity, lyso-Gb3 accumulation and GLA gene sequencing" Open
View article: Genotype-Phenotype correlation of 17 cases of Pompe Disease in Spanish Patients and Identification of 4 Novel Mutations
Genotype-Phenotype correlation of 17 cases of Pompe Disease in Spanish Patients and Identification of 4 Novel Mutations Open
Background: Pompe disease (PD) is an autosomal recessive metabolic disorder caused by mutations in the acid α-glucosidase gene ( GAA ) that produces defects in the lysosomal acid α-1,4-glucosidase. We aimed to identify genetic variations a…
View article: Anxiolytic-Like Effects of Lupinus angustifolious Protein Hydrolysates in Alzheimer Model Mice
Anxiolytic-Like Effects of Lupinus angustifolious Protein Hydrolysates in Alzheimer Model Mice Open
Alzheimer’s disease (AD), which is characterized by a devastating and progressive loss of memory, is the principal neurodegenerative disease in the elderly population worldwide. As a consequence, AD patients present neuropsychiatric sympto…
View article: Intra-Axial Frontal Cyst with Ependymoma-Like Proliferation: Neuroectodermal or Neurenteric?
Intra-Axial Frontal Cyst with Ependymoma-Like Proliferation: Neuroectodermal or Neurenteric? Open
To the Editor:Intracranial cysts are classified into 3 main categories based on their embryologic origin: ectodermal (such as epidermoid and dermoid cysts), neuroectodermal (including arachnoid, choroid plexus, and ependymal/glioependymal …
View article: Immunomodulatory and Antioxidant Properties of Wheat Gluten Protein Hydrolysates in Human Peripheral Blood Mononuclear Cells
Immunomodulatory and Antioxidant Properties of Wheat Gluten Protein Hydrolysates in Human Peripheral Blood Mononuclear Cells Open
Peptides from several plant food proteins not only maintain the nutritional values of the original protein and decrease the environmental impact of animal agriculture, but also exert biological activities with significant health-beneficial…
View article: Lupine protein hydrolysates decrease the inflammatory response and improve the oxidative status in human peripheral lymphocytes
Lupine protein hydrolysates decrease the inflammatory response and improve the oxidative status in human peripheral lymphocytes Open
View article: Temporal expression patterns of the melatoninergic system in the human thymus of children
Temporal expression patterns of the melatoninergic system in the human thymus of children Open
View article: Peripheral CD39-expressing T regulatory cells are increased and associated with relapsing-remitting multiple sclerosis in relapsing patients
Peripheral CD39-expressing T regulatory cells are increased and associated with relapsing-remitting multiple sclerosis in relapsing patients Open
View article: Family study of a novel mutation of mucopolysaccharidosis type VI with a severe phenotype and good response to enzymatic replacement therapy
Family study of a novel mutation of mucopolysaccharidosis type VI with a severe phenotype and good response to enzymatic replacement therapy Open
Rationale: Mucopolysaccharidosis type VI (MPS VI) or Maroteaux-Lamy syndrome is produced by the deficiency of the enzyme arylsulfatase B, responsible for the hydrolysis of N-acetyl-D-galactosamine, chondroitin sulfate, and dermatan sulfate…
View article: Effects of immediate‐release niacin and dietary fatty acids on acute insulin and lipid status in individuals with metabolic syndrome
Effects of immediate‐release niacin and dietary fatty acids on acute insulin and lipid status in individuals with metabolic syndrome Open
BACKGROUND The nature of dietary fats profoundly affects postprandial hypertriglyceridemia and glucose homeostasis. Niacin is a potent lipid‐lowering agent. However, limited data exist on postprandial triglycerides and glycemic control fol…
View article: Medicaments administration into the subtenon eye space in treatment of anterior ischemic neuropathy.
Medicaments administration into the subtenon eye space in treatment of anterior ischemic neuropathy. Open
In spite of treatment provided in anterior ischemic neuropathy, a prognosis for visual functions is poor and depends on severity of affection of vascular system of the body. We have studied the exposure to cortexin and diprospan in subteno…
View article: Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis
Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis Open
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View article: Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis
Circulating cell-free DNA is a predictor of short-term neurological outcome in stroke patients treated with intravenous thrombolysis Open
Circulating cell-free DNA (cfDNA) has been described as a prognostic marker for several diseases. Its prognostic value for short-term outcome in stroke patients treated with intravenous thrombolysis remains unexplored. cfDNA was measured o…
View article: The utility of C-reactive protein and procalcitonin for sepsis diagnosis in critically burned patients: A preliminary study
The utility of C-reactive protein and procalcitonin for sepsis diagnosis in critically burned patients: A preliminary study Open
Objective To assess the utility of C-reactive protein (CRP) and procalcitonin (PCT) as biomarkers of infection in patients with severe burn injury. Methods The present study included severe burn injury patients consecutively admitted to th…