Judith Hoffmann
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View article: Adaptations of <i>Pseudoxylaria</i> towards a comb-associated lifestyle in fungus-farming termite colonies
Adaptations of <i>Pseudoxylaria</i> towards a comb-associated lifestyle in fungus-farming termite colonies Open
Characterizing ancient clades of fungal symbionts is necessary for understanding the evolutionary process underlying symbiosis development. In this study, we investigated a distinct subgeneric taxon of Xylaria (Xylariaceae), named Pseudoxy…
View article: Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin**
Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin** Open
Herein, we describe the myxobacterial natural product Corramycin isolated from Corallococcus coralloides . The linear peptide structure contains an unprecedented (2 R ,3 S )‐γ‐ N ‐methyl‐β‐hydroxy‐histidine moiety. Corramycin exhibits anti…
View article: Strukturaufklärung, Totalsynthese, In‐Vivo‐Aktivität und Potentieller Biosyntheseweg des Neuen Myxobakteriellen Antibiotikums Corramycin**
Strukturaufklärung, Totalsynthese, In‐Vivo‐Aktivität und Potentieller Biosyntheseweg des Neuen Myxobakteriellen Antibiotikums Corramycin** Open
Im Folgenden beschreiben wir das aus dem Myxobakterium Corallococcus coralloides isolierte Antibiotikum Corramycin. Die lineare Peptidstruktur enthält eine bislang unbeschriebene (2 R ,3 S )‐γ‐ N ‐Methyl‐β‐hydroxyhistidin‐Einheit. Corramyc…
View article: Structure elucidation, biosynthesis, total synthesis and antibacterial in-vivo efficacy of myxobacterial Corramycin
Structure elucidation, biosynthesis, total synthesis and antibacterial in-vivo efficacy of myxobacterial Corramycin Open
Herein, we describe the myxobacterial natural product Corramycin (1) isolated from Corallococcus coralloides (C. coralloides). Corramycin is a linear peptide containing an unprecedented (2R,3S) N-methyl-β-hydroxy histidine moiety and exh…
View article: Front Cover: Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non‐8‐ene (ChemBioChem 6/2019)
Front Cover: Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non‐8‐ene (ChemBioChem 6/2019) Open
The front cover picture shows the biosynthesis illustration of armeniaspirols, which contain an unusual spiro[4.4]non-8-ene moiety. The lake can be seen as a precursor pool for the biosynthesis of bacterial secondary metabolites. The chlor…
View article: Theater in Bedrängnis
Theater in Bedrängnis Open
Im Zentrum der Arbeit steht die Untersuchung der komplexen und multidimensionalen Rolle der beiden Madrider Volkstheater im ausgehenden 18. Jahrhundert. Unter dem Postulat einer neu eintretenden funktionalen Ausdifferenzierung der Gesellsc…
View article: CCDC 1463242: Experimental Crystal Structure Determination
CCDC 1463242: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Pinensine: Die ersten antimykotischen Lantibiotika
Pinensine: Die ersten antimykotischen Lantibiotika Open
Lantibiotika (Lanthionin enthaltende Antibiotika) aus Gram‐positiven Bakterien wirken üblicherweise antibakteriell auf Gram‐positive Keime. Wir beschreiben hier die Aktivität und Struktur der Pinensine A ( 1 ) und B ( 2 ), der ersten aus e…