Judith Meek
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View article: Clinical value of cortical bursting in preterm infants with intraventricular haemorrhage
Clinical value of cortical bursting in preterm infants with intraventricular haemorrhage Open
Cortical bursting can index the functional injury after GM-IVH: perturbed burst initiation (rate) and propagation (inter-hemispheric dynamics) likely reflect associated grey matter and white matter damage. Higher cortical burst rate is rea…
View article: Clinical value of cortical bursting in preterm infants with intraventricular haemorrhage
Clinical value of cortical bursting in preterm infants with intraventricular haemorrhage Open
Objective In healthy preterm infants, cortical burst rate and temporal dynamics predict important measures such as brain growth. We hypothesised that in preterm infants with germinal matrix-intraventricular haemorrhage (GM-IVH), cortical b…
View article: Feasibility of smartphone colorimetry of the face as an anaemia screening tool for infants and young children in Ghana
Feasibility of smartphone colorimetry of the face as an anaemia screening tool for infants and young children in Ghana Open
Background Anaemia affects approximately a quarter of the global population. When anaemia occurs during childhood, it can increase susceptibility to infectious diseases and impair cognitive development. This research uses smartphone-based …
View article: 1367 Outcomes of admission of late preterm babies in transitional care
1367 Outcomes of admission of late preterm babies in transitional care Open
Aims BAPM guidance 2017 endorses admission in Transitional Care (TC) of late preterm 34-35 weeks who do not fulfill criteria for intensive or high dependency care, given its potential benefits as facilitation of baby-led feeding, greater p…
View article: Neonatal jaundice in Ghanaian children: Assessing maternal knowledge, attitude, and perceptions
Neonatal jaundice in Ghanaian children: Assessing maternal knowledge, attitude, and perceptions Open
Background Neonatal jaundice (NNJ) is a major cause of preventable childhood mortality and long-term impairment especially in countries with significant prevalence of the inherited condition, glucose-6-phosphate dehydrogenase (G6PD) defect…
View article: Cerebral Near Infrared Spectroscopy Monitoring in Term Infants With Hypoxic Ischemic Encephalopathy—A Systematic Review
Cerebral Near Infrared Spectroscopy Monitoring in Term Infants With Hypoxic Ischemic Encephalopathy—A Systematic Review Open
Background: Neonatal hypoxic ischemic encephalopathy (HIE) remains a significant cause of mortality and morbidity worldwide. Cerebral near infrared spectroscopy (NIRS) can provide cot side continuous information about changes in brain hemo…
View article: Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity
Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity Open
Jaundice is a major cause of mortality and morbidity in the newborn. Globally, early identification and home monitoring are significant challenges in reducing the incidence of jaundice-related neurological damage. Smartphone cameras are pr…
View article: Near-Infrared Spectroscopy Measured Cerebral Blood Flow from Spontaneous Oxygenation Changes in Neonatal Brain Injury
Near-Infrared Spectroscopy Measured Cerebral Blood Flow from Spontaneous Oxygenation Changes in Neonatal Brain Injury Open
Neonates with hypoxic-ischaemic (HI) brain injury were monitored using a broadband near-infrared spectroscopy (NIRS) system in the neonatal intensive care unit. The aim of this work is to use the NIRS cerebral oxygenation data (HbD = oxyge…
View article: Core temperature after birth in babies with neonatal encephalopathy in a sub‐Saharan African hospital setting
Core temperature after birth in babies with neonatal encephalopathy in a sub‐Saharan African hospital setting Open
Key points Therapeutic hypothermia (HT) to 33.0–34.0°C for 72 h provides optimal therapy for infants with neonatal encephalopathy (NE) in high‐resource settings. HT is not universally implemented in low‐ and middle‐income countries as a re…
View article: Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity:<i>neoSCB</i>app pilot study
Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity:<i>neoSCB</i>app pilot study Open
Jaundice is a major cause of mortality and morbidity in the newborn. Globally, early identification and home monitoring are significant challenges in reducing the incidence of jaundice-related neurological damage. Smartphone cameras are pr…
View article: Investigation of the Pattern of the Hemodynamic Response as Measured by Functional Near-Infrared Spectroscopy (fNIRS) Studies in Newborns, Less Than a Month Old: A Systematic Review
Investigation of the Pattern of the Hemodynamic Response as Measured by Functional Near-Infrared Spectroscopy (fNIRS) Studies in Newborns, Less Than a Month Old: A Systematic Review Open
It has been 20 years since functional near-infrared spectroscopy (fNIRS) was first used to investigate the evoked hemodynamic response to a stimulus in newborns. The hemodynamic response to functional activation is well-established in adul…
View article: Oxygen dependency of mitochondrial metabolism indicates outcome of newborn brain injury
Oxygen dependency of mitochondrial metabolism indicates outcome of newborn brain injury Open
There is a need for a method of real-time assessment of brain metabolism during neonatal hypoxic-ischaemic encephalopathy (HIE). We have used broadband near-infrared spectroscopy (NIRS) to monitor cerebral oxygenation and metabolic changes…
View article: Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury
Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury Open
Hypoxic ischemic encephalopathy (HIE) leads to significant morbidity and mortality. Impaired autoregulation after hypoxia-ischaemia has been suggested to contribute further to injury. Thalamic lactate/N-Acetylasperate (Lac/NAA) peak area r…
View article: Changes in Cerebral Oxidative Metabolism during Neonatal Seizures Following Hypoxic–Ischemic Brain Injury
Changes in Cerebral Oxidative Metabolism during Neonatal Seizures Following Hypoxic–Ischemic Brain Injury Open
Seizures are common following hypoxic-ischemic brain injury in newborn infants. Prolonged or recurrent seizures have been shown to exacerbate neuronal damage in the developing brain; however, the precise mechanism is not fully understood. …
View article: In Vivo Measurement of Cerebral Mitochondrial Metabolism Using Broadband Near Infrared Spectroscopy Following Neonatal Stroke
In Vivo Measurement of Cerebral Mitochondrial Metabolism Using Broadband Near Infrared Spectroscopy Following Neonatal Stroke Open
Neonatal stroke presents with features of encephalopathy and can result in significant morbidity and mortality. We investigated the cerebral metabolic and haemodynamic changes following neonatal stroke in a term infant at 24 h of life. Cha…