Judy L. Thompson
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View article: Collecting language, speech acoustics, and facial expression to predict psychosis and other clinical outcomes: strategies from the AMP® SCZ initiative
Collecting language, speech acoustics, and facial expression to predict psychosis and other clinical outcomes: strategies from the AMP® SCZ initiative Open
Speech-based detection of early psychosis is progressing at a rapid pace. Within this evolving field, the Accelerating Medicines Partnership® in Schizophrenia (AMP® SCZ) is uniquely positioned to deepen our understanding of how language an…
View article: Bodily Self-Disturbances and Hallucinations in Schizophrenia
Bodily Self-Disturbances and Hallucinations in Schizophrenia Open
Background and Hypothesis Auditory verbal hallucinations experienced by people with schizophrenia are primarily described in terms of unusual perceptual experiences. However, they also involve profound self-disturbances. More specifically,…
View article: Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program
Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program Open
Clinical ascertainment and clinical outcome are key features of any large multisite study. In the ProNET and PRESCIENT research networks, the Accelerating Medicines Partnership® Schizophrenia (AMP®SCZ) Clinical Ascertainment and Outcome Me…
View article: The MR neuroimaging protocol for the Accelerating Medicines Partnership® Schizophrenia Program
The MR neuroimaging protocol for the Accelerating Medicines Partnership® Schizophrenia Program Open
Neuroimaging with MRI has been a frequent component of studies of individuals at clinical high risk (CHR) for developing psychosis, with goals of understanding potential brain regions and systems impacted in the CHR state and identifying p…
View article: Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample
Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample Open
Cognitive impairment occurs at higher rates in individuals at clinical high risk (CHR) for psychosis relative to healthy peers, and it contributes unique variance to multivariate prediction models of transition to psychosis. Such impairmen…
View article: Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program
Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program Open
Background This paper focuses on the baseline clinical characterization of the participants in the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) program. The AMP SCZ program is designed to investigate a wide array of clinical …
View article: Sample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program
Sample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program Open
Background This paper presents the recruitment sources of clinical high-risk (CHR) and community controls (CC) from the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) program, which aims to study various clinical variables and …
View article: Performance on a contour integration task as a function of contour shape in schizophrenia and controls
Performance on a contour integration task as a function of contour shape in schizophrenia and controls Open
Contour Integration (CI) is the ability to integrate elemental features into objects and is a basic visual process essential for object perception and recognition, and for functioning in visual environments. It is now well documented that …
View article: High Spatial Frequency Stimuli Amplify Visual Integration Deficits in Schizophrenia and Bipolar Disorder
High Spatial Frequency Stimuli Amplify Visual Integration Deficits in Schizophrenia and Bipolar Disorder Open
Background. Schizophrenia patients poorly integrate oriented elements into cohesive contours. The deficit worsens as the stimulus is globally scaled down in size (Keane et al., 2016), but it is unknown which stimulus features are driving t…
View article: Retinal Neurodegeneration as a Potential Biomarker of Accelerated Aging in Schizophrenia Spectrum Disorders
Retinal Neurodegeneration as a Potential Biomarker of Accelerated Aging in Schizophrenia Spectrum Disorders Open
Background and Hypotheses Several biological markers are believed to reflect accelerated aging in schizophrenia spectrum disorders; however, retinal neural changes have not yet been explored as potential CNS biomarkers of accelerated aging…
View article: Characterization of training profiles between individuals with schizophrenia and healthy individuals on Contrast Detection and Contour Integration tasks
Characterization of training profiles between individuals with schizophrenia and healthy individuals on Contrast Detection and Contour Integration tasks Open
Schizophrenia is a chronic psychiatric condition that is generally characterized by hallucinations, delusions, and trouble with speech and thinking. In addition, this condition is characterized by alterations in visual perception. As such,…
View article: Performance on a Contour Integration task as a function of Contour Shapes: A comparison study between individuals with schizophrenia and Neurotypical Individuals
Performance on a Contour Integration task as a function of Contour Shapes: A comparison study between individuals with schizophrenia and Neurotypical Individuals Open
Contour Integration (CI) is the ability to integrate elemental features into objects and is a basic visual process required to recognize target objects in a visually noisy environment. The ability to accurately identify contour shapes foll…
View article: Brain network mechanisms of visual perceptual organization in schizophrenia and bipolar disorder
Brain network mechanisms of visual perceptual organization in schizophrenia and bipolar disorder Open
Visual shape completion is a canonical perceptual organization process that integrates spatially distributed edge information into unified representations of objects. People with schizophrenia show difficulty in discriminating completed sh…
View article: Predicting Attention-Shaping Response in People With Schizophrenia
Predicting Attention-Shaping Response in People With Schizophrenia Open
People with schizophrenia often experience attentional impairments that hinder learning during psychological interventions. Attention shaping is a behavioral technique that improves attentiveness in this population. Because reinforcement l…
View article: Discovering Knowledge Through Visual Analysis
Discovering Knowledge Through Visual Analysis Open
This paper describes a vision for the near future in digital content analysis as it relates to the creation, verification, and presentation of knowledge. This paper focuses on how visualization enables humans to gain knowledge. Visualizati…
View article: Development and Evaluation of a Visual Remediation Intervention for People with Schizophrenia
Development and Evaluation of a Visual Remediation Intervention for People with Schizophrenia Open
It is now well documented that schizophrenia is associated with impairments in visual processing at all levels of vision, and that these disturbances are related to deficits in multiple higher-level cognitive and social cognitive functions…
View article: F25. EVALUATION OF A VISUAL REMEDIATION INTERVENTION FOR SCHIZOPHRENIA
F25. EVALUATION OF A VISUAL REMEDIATION INTERVENTION FOR SCHIZOPHRENIA Open
Schizophrenia is associated with visual-processing abnormalities, including impairments in visual acuity, low-contrast stimulus detection, and perceptual organization (i.e., perceiving visual information in an organized “perceptual whole”)…
View article: 7.1 ELECTRORETINOGRAPHIC ANOMALIES IN SCHIZOPHRENIA AND THEIR RELATIONSHIPS WITH RETINAL STRUCTURE, VISUAL FUNCTIONS, CLINICAL SYMPTOMS, AND MEDICAL COMORBIDITIES
7.1 ELECTRORETINOGRAPHIC ANOMALIES IN SCHIZOPHRENIA AND THEIR RELATIONSHIPS WITH RETINAL STRUCTURE, VISUAL FUNCTIONS, CLINICAL SYMPTOMS, AND MEDICAL COMORBIDITIES Open
Although several studies have documented retinal cell dysfunction in schizophrenia (Silverstein & Rosen, Scz Res: Cogn, 2015), the extent to which these abnormalities contribute to, and/or result from, other features of the condition is un…
View article: Evaluation of a cognitive remediation intervention for college students with psychiatric conditions.
Evaluation of a cognitive remediation intervention for college students with psychiatric conditions. Open
FAST may lead to an increase in self-efficacy and cognitive strategy use, as well as a reduction in academic difficulties among students with psychiatric conditions. Future analyses with follow-up data through 12 months will address the po…