Juhana Hakumäki
YOU?
Author Swipe
View article: MRI edema patterns in acute neck infections: A multicenter and multidisciplinary interobserver study
MRI edema patterns in acute neck infections: A multicenter and multidisciplinary interobserver study Open
Physicians reliably detect MRI edema patterns across expertise levels, validating their use for risk stratification in acute neck infections and supporting broader adoption in clinical practice where MRI is available.
View article: Children born small-for-gestational-age exhibit normal body fat but elevated hs-CRP and hepatocellular lipid content
Children born small-for-gestational-age exhibit normal body fat but elevated hs-CRP and hepatocellular lipid content Open
Background/objectives Being born small-for-gestational-age (SGA), is associated with an increased risk of cardiometabolic disease in adulthood. We studied the influence of birth size on hepatocellular lipid (HCL) concentrations in prepuber…
View article: Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1
Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1 Open
Objective Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B ( CSTB ) gene. Despite a progressive course, phenotype severity varies among patients, even within familie…
View article: Brain Ventricle Morphology Markers in Predicting Shunt Surgery Outcome in Idiopathic Normal-Pressure Hydrocephalus
Brain Ventricle Morphology Markers in Predicting Shunt Surgery Outcome in Idiopathic Normal-Pressure Hydrocephalus Open
Background Idiopathic normal pressure hydrocephalus (iNPH) is characterized by a clinical triad of symptoms: abnormal gait, memory problems, and urinary incontinence. Neuroimaging plays a crucial role in diagnosing iNPH. However, current r…
View article: Left ventricular septal convexity in differentiating hypertrophic cardiomyopathy from hypertensive heart disease – a cardiac magnetic resonance study
Left ventricular septal convexity in differentiating hypertrophic cardiomyopathy from hypertensive heart disease – a cardiac magnetic resonance study Open
Both hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD) are characterized by left ventricular hypertrophy. Distinguishing HCM from HHD is a common clinical problem, particularly in subjects with moderate left ventricula…
View article: Fiber orientation‐dependent T<sub>1</sub> angular features in human white matter at 1.5 T, 3 T, and 7 T
Fiber orientation‐dependent T<sub>1</sub> angular features in human white matter at 1.5 T, 3 T, and 7 T Open
Purpose White matter (WM) microstructure influences T 1 in vivo. Here, T 1 angular features were studied in human WM in vivo in quantitative terms at 1.5 T, 3 T and 7 T. Methods MP2RAGE MRI was used to compute absolute T 1 images of the br…
View article: Real‐world brain imaging in a population‐based cohort enables accurate markers for dementia
Real‐world brain imaging in a population‐based cohort enables accurate markers for dementia Open
INTRODUCTION Although a vast amount of magnetic resonance imaging (MRI) data are collected for health care delivery, generating real‐world evidence (RWE) in Alzheimer's disease and related dementias (ADRD) research is substantially limited…
View article: Monoallelic TYROBP deletion is a novel risk factor for Alzheimer’s disease
Monoallelic TYROBP deletion is a novel risk factor for Alzheimer’s disease Open
View article: Comparative Clinical and Imaging‐Based Evaluation of Therapeutic Modalities in CNS Embryonal Tumours With PLAGL Amplification
Comparative Clinical and Imaging‐Based Evaluation of Therapeutic Modalities in CNS Embryonal Tumours With PLAGL Amplification Open
Aims Embryonal tumours with PLAGL1 or PLAGL2 amplification (ET, PLAGL) show substantial heterogeneity regarding their clinical characteristics and have been treated inconsistently, resulting in diverse outcomes. In this study, we aimed to …
View article: Effect of ventricular volume on cerebrospinal fluid Alzheimer's disease biomarkers in patients with idiopathic normal pressure hydrocephalus
Effect of ventricular volume on cerebrospinal fluid Alzheimer's disease biomarkers in patients with idiopathic normal pressure hydrocephalus Open
Background Idiopathic normal pressure hydrocephalus (iNPH) is a common disorder in aging populations. Alzheimer's disease (AD) is a significant comorbidity in iNPH patients, and the presence of AD pathology is associated with worse shuntin…
View article: Real-world brain imaging in a population-based cohort enables accurate markers for dementia
Real-world brain imaging in a population-based cohort enables accurate markers for dementia Open
INTRODUCTION While a vast amount of MRI data are collected for healthcare delivery, generating real-world evidence (RWE) in Alzheimer’s and related diseases (ADRD) research is substantially limited by lack of methods and results showing ho…
View article: Orbitofrontal Atrophy on MRI Appears to Be an Indicator of C9orf72 Repeat Expansion Status in FTD
Orbitofrontal Atrophy on MRI Appears to Be an Indicator of C9orf72 Repeat Expansion Status in FTD Open
View article: Differentiating Parkinson‐Plus Syndromes from Other Neurodegenerative Diseases Using Automated T1 MRI Quantification
Differentiating Parkinson‐Plus Syndromes from Other Neurodegenerative Diseases Using Automated T1 MRI Quantification Open
Background Accurate differential diagnosis of neurodegenerative diseases is challenging, but crucial for the management and treatment, particularly given the development of disease‐modifying drug therapies for Alzheimer’s disease (AD). In …
View article: Increased background parenchymal enhancement on peri-menopausal breast magnetic resonance imaging
Increased background parenchymal enhancement on peri-menopausal breast magnetic resonance imaging Open
Objectives: To examine the background parenchymal enhancement (BPE) levels in peri-menopausal breast MRI compared with pre- and post-menopausal breast MRI. Methods: This study included 562 patients (55.8±12.3 years) who underwent contrast-…
View article: ETMR-28. EVALUATING THERAPEUTIC APPROACHES IN EMBRYONAL TUMORS WITH PLAGL1 AND PLAGL2 AMPLIFICATION AND UNRAVELING MOLECULAR PARALLELS IN EPIGENETICALLY RELATED TUMORS WITH PLAG1-ALTERATIONS
ETMR-28. EVALUATING THERAPEUTIC APPROACHES IN EMBRYONAL TUMORS WITH PLAGL1 AND PLAGL2 AMPLIFICATION AND UNRAVELING MOLECULAR PARALLELS IN EPIGENETICALLY RELATED TUMORS WITH PLAG1-ALTERATIONS Open
BACKGROUND Embryonal tumors with PLAGL1 and PLAGL2 amplification (ET, PLAGL) display substantial clinical heterogeneity regarding applied treatment and outcomes. As a recently-defined entity, the spectrum of tumor-driving PLAG-family alter…
View article: Monoallelic<i>TYROBP</i>deletion is a novel risk factor for Alzheimer’s disease
Monoallelic<i>TYROBP</i>deletion is a novel risk factor for Alzheimer’s disease Open
Biallelic loss-of-function variants in TYROBP and TREM2 cause autosomal recessive presenile dementia with bone cysts known as Nasu-Hakola disease (NHD, alternatively polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopa…
View article: Progressive myoclonic epilepsy type 1 (EPM1) patients present with abnormal 1H MRS brain metabolic profiles associated with cognitive function
Progressive myoclonic epilepsy type 1 (EPM1) patients present with abnormal 1H MRS brain metabolic profiles associated with cognitive function Open
View article: Progressive Myoclonic Epilepsy Type 1 (EPM1) Patients Present with Abnormal 1H MRS Brain Metabolic Profiles Associated with Cognitive Function
Progressive Myoclonic Epilepsy Type 1 (EPM1) Patients Present with Abnormal 1H MRS Brain Metabolic Profiles Associated with Cognitive Function Open
View article: Self-evaluation of computed tomography use in the diagnosis of coronary artery disease
Self-evaluation of computed tomography use in the diagnosis of coronary artery disease Open
Poster: EuroSafe Imaging 2017 / ESI-0044 / Self-evaluation of computed tomography use in the diagnosis of coronary artery disease by: Hakumaki1, J. Vienonen2, M. Hedman2, P. Saari2, H. Matikka2, M. Husso3, R. Vanninen2; 1 KYS, Kuop…
View article: Diffusion-Weighted Imaging in 3.0 Tesla Breast MRI: Diagnostic Performance and Tumor Characterization Using Small Subregions vs. Whole Tumor Regions of Interest
Diffusion-Weighted Imaging in 3.0 Tesla Breast MRI: Diagnostic Performance and Tumor Characterization Using Small Subregions vs. Whole Tumor Regions of Interest Open
ADC values assist in breast tumor characterization. Small ROIs were more accurate than whole-lesion ROIs and more frequently associated with prognostic factors. Cut-off values differed significantly depending on measurement procedure, whic…
View article: Preoperative Axillary Staging with 3.0-T Breast MRI: Clinical Value of Diffusion Imaging and Apparent Diffusion Coefficient
Preoperative Axillary Staging with 3.0-T Breast MRI: Clinical Value of Diffusion Imaging and Apparent Diffusion Coefficient Open
The axillary staging in newly diagnosed breast cancer is under major evolution. The aims of this study were to define the diagnostic performance of 3.0-T diffusion-weighted imaging (DWI) in the detection of axillary metastases in newly dia…