Julia Arebro
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View article: Subacute Mastoiditis Without Verified Nontuberculous Mycobacteria—Still a Clinical Challenge
Subacute Mastoiditis Without Verified Nontuberculous Mycobacteria—Still a Clinical Challenge Open
Objective An indolent form of mastoiditis has gained increased attention lately, challenging clinicians both regarding diagnosis as well as treatment. The etiology behind this assumed infection herein named subacute mastoiditis (SAM) is un…
View article: The complexity of acute mastoiditis in Swedish children
The complexity of acute mastoiditis in Swedish children Open
Chart validity assessment is needed in larger retrospective studies on AM where cases are identified using ICD-10 diagnosis code. The introduction of PCV has decreased the cases of AM in children <2 years.
View article: Nasal production of IL-26 involving T cells in smokers with and without chronic obstructive pulmonary disease
Nasal production of IL-26 involving T cells in smokers with and without chronic obstructive pulmonary disease Open
In the nasal cavity, IL-26 can be produced by local T cells. This IL-26 reflects bronchoalveolar pathology and clinical symptoms, thereby constituting an accessible target with potential for clinically relevant endotyping in COPD.
View article: Bilateral intracochlear hemorrhage: A rare onset of chronic myelogenous leukemia
Bilateral intracochlear hemorrhage: A rare onset of chronic myelogenous leukemia Open
Key Clinical Message Acute onset of vertigo and hearing loss is rare in leukemic disorders. MRI can diagnose intracochlear hemorrhage as the underlying cause. The hearing can improve but if severe hearing loss preserves, cochlear implantat…
View article: Delayed neutrophil shedding of CD62L in patients with chronic rhinosinusitis with nasal polyps and asthma: Implications for <i>Staphylococcus aureus</i> colonization and corticosteroid treatment
Delayed neutrophil shedding of CD62L in patients with chronic rhinosinusitis with nasal polyps and asthma: Implications for <i>Staphylococcus aureus</i> colonization and corticosteroid treatment Open
Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the sinonasal mucosa that is often accompanied by local Staphylococcus aureus colonization,1 as well as comorbid asthma.2 Although both CRSwNP and asthma are a…
View article: Cancer-Associated Fibroblast Heterogeneity in Malignancy with Focus on Oral Squamous Cell Carcinoma
Cancer-Associated Fibroblast Heterogeneity in Malignancy with Focus on Oral Squamous Cell Carcinoma Open
Oral squamous cell carcinoma (OSCC) remains an understudied and significant global cancer killer and dismal survival rates have not changed in decades. A better understanding of the molecular basis of OSCC progression and metastasis is nee…
View article: Cancer‐Associated Fibroblast Heterogeneity in Oral Cancer
Cancer‐Associated Fibroblast Heterogeneity in Oral Cancer Open
Oral squamous cell carcinoma (OSCC) remains an under-studied and significant global cancer killer and dismal survival rates have not changed in decades. A better understanding of the molecular basis of OSCC progression and metastasis is ne…
View article: Extracellular vesicles promote activation of pro-inflammatory cancer-associated fibroblasts in oral cancer
Extracellular vesicles promote activation of pro-inflammatory cancer-associated fibroblasts in oral cancer Open
Introduction: Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancer and has a survival rate of ∼50% over 5 years. New treatment strategies are sorely needed to improve survival rates—and a better understanding…
View article: Postsurgical pyoderma gangrenosum and flap necrosis in a head and neck cancer patient following neck dissection
Postsurgical pyoderma gangrenosum and flap necrosis in a head and neck cancer patient following neck dissection Open
Postsurgical pyoderma gangrenosum (PSPG) develops in the skin after surgery without known cause. Immunosuppression constitutes first‐line therapy and increases the likelihood of successful surgery when needed. PSPG should be considered whe…
View article: The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps
The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps Open
BACKGROUND: Chronic rhinosinusitis (CRS) is a common yet under-recognised chronic inflammatory disease of the nose and paranasal sinuses that is classified according to the presence (CRSwNP) or absence (CRSsNP) of nasal polyps. METHODS: Th…
View article: The GALEN rhinosinusitis cohort: chronic rhinosinusitis with nasal polyps affects health-related quality of life
The GALEN rhinosinusitis cohort: chronic rhinosinusitis with nasal polyps affects health-related quality of life Open
CRSwNP patients have significantly lower HRQoL compared with population norms. The impact is greater in patients with greater disease severity, comorbidities, or refractory disease.
View article: Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps Open
View article: Innate mechanisms in upper airway inflammation with focus on epithelium and neutrophils
Innate mechanisms in upper airway inflammation with focus on epithelium and neutrophils Open
Mucosal inflammation is a key feature in allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP). The traditional idea of the epithelium as a simple barrier and neutrophils as a homogenous cell population, already term…
View article: A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification Open
View article: Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers
Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers Open
View article: Antigen-presenting epithelial cells can play a pivotal role in airway allergy
Antigen-presenting epithelial cells can play a pivotal role in airway allergy Open
View article: The ‘GA²LEN Sinusitis Cohort’: an introduction
The ‘GA²LEN Sinusitis Cohort’: an introduction Open
The Global Allergy and Asthma European Network (GA2LEN) is a network of the leading European allergy clinical and research facilities and the GA2LEN Sinusitis Cohort is a database within this network. The aim of this cohort is to intensify…
View article: Antigen presenting epithelial cells play a pivotal role in airway allergy
Antigen presenting epithelial cells play a pivotal role in airway allergy Open
Epithelial cells are known to express MHC class II, but their ability to process and present allergens thus contributing to the development of upper airway disease is unclear. The aim of this study was to establish antigen presenting nasal…