Julia Bohlius
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View article: Generative Artificial Intelligence for Data Analysis: A Randomised Controlled Trial in a Public Health Research Institute
Generative Artificial Intelligence for Data Analysis: A Randomised Controlled Trial in a Public Health Research Institute Open
Objective To assess the competence of students and academic staff to use generative artificial intelligence (GenAI) as a tool in epidemiological data analyses in a randomised controlled trial (RCT). Methods We invited postgraduate students…
View article: HIV-1 Viremia and Cancer Risk in 2.8 Million People: The South African HIV Cancer Match Study
HIV-1 Viremia and Cancer Risk in 2.8 Million People: The South African HIV Cancer Match Study Open
Background Most research on human immunodeficiency virus-1 (HIV-1) viremia and cancer risk is from high-income countries. We evaluated the association between HIV-1 viremia and the risk of various cancer types among people with HIV (PWH) i…
View article: Cervical cancer prevention and care in HIV clinics across sub‐Saharan Africa: results of a facility‐based survey
Cervical cancer prevention and care in HIV clinics across sub‐Saharan Africa: results of a facility‐based survey Open
INTRODUCTION To eliminate cervical cancer (CC), access to and quality of prevention and care services must be monitored, particularly for women living with HIV (WLHIV). We assessed implementation practices in HIV clinics across sub‐Saharan…
View article: Breast cancer in women by HIV status: A report from the South African National Cancer Registry
Breast cancer in women by HIV status: A report from the South African National Cancer Registry Open
Background Breast cancer (BC) is the leading cause of cancer-related morbidity and mortality in women living in South Africa, a country with a high HIV burden. However, characteristics of the double burden of HIV and BC in South Africa hav…
View article: Cancer diagnostic service use in people living with HIV in South Africa: A cross-sectional study
Cancer diagnostic service use in people living with HIV in South Africa: A cross-sectional study Open
Objective The objective of this study was to map place of cancer diagnosis in relation to Human Immunodeficiency Virus (HIV) care centre among people living with HIV (PLHIV) within South Africa (SA) using national laboratory database. Desi…
View article: Impact of the 2013 WHO guidelines for screening and treatment of cervical precancerous lesions on women’s screening rates, by HIV-status, in East and Southern Africa: A regression discontinuity design analysis
Impact of the 2013 WHO guidelines for screening and treatment of cervical precancerous lesions on women’s screening rates, by HIV-status, in East and Southern Africa: A regression discontinuity design analysis Open
Introduction In 2013, the World Health Organization (WHO) issued guidelines for cervical pre-cancer screening. It recommended screening women aged 30–49, and younger women once they tested HIV-positive. Subsequent WHO guidelines recommende…
View article: Competencies for Transformational Leadership in Public Health—An International Delphi Consensus Study
Competencies for Transformational Leadership in Public Health—An International Delphi Consensus Study Open
Objectives: This Delphi study intended to develop competencies for transformational leadership in public health, including behavioral descriptions (descriptors) tailored to individuals and their contexts. Methods: The study involved five r…
View article: Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia
Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia Open
Objective This study aimed to provide evidence to improve cervical screening for women living with HIV (WLHIV). We assessed the accuracy of screening tests that can be used in low-resource settings and give results at the same visit. Metho…
View article: Facility-Based Indicators to Manage and Scale Up Cervical Cancer Prevention and Care Services for Women Living With HIV in Sub-Saharan Africa: a Three-Round Online Delphi Consensus Method
Facility-Based Indicators to Manage and Scale Up Cervical Cancer Prevention and Care Services for Women Living With HIV in Sub-Saharan Africa: a Three-Round Online Delphi Consensus Method Open
Background: Of women with cervical cancer (CC) and HIV, 85% live in sub-Saharan Africa, where 21% of all CC cases are attributable to HIV infection. We aimed to generate internationally acceptable facility-based indicators to monitor and g…
View article: State of the science and future directions for research on <scp>HIV</scp> and cancer: Summary of a joint workshop sponsored by <scp>IARC</scp> and <scp>NCI</scp>
State of the science and future directions for research on <span>HIV</span> and cancer: Summary of a joint workshop sponsored by <span>IARC</span> and <span>NCI</span> Open
An estimated 38 million people live with human immunodeficiency virus (HIV) worldwide and are at excess risk for multiple cancer types. Elevated cancer risks in people living with HIV (PLWH) are driven primarily by increased exposure to ca…
View article: Cancer diagnostic service use in people with HIV in South Africa: a cross-sectional study
Cancer diagnostic service use in people with HIV in South Africa: a cross-sectional study Open
Objective The objective of this study was to map place of cancer diagnosis in relation to Human Immunodeficiency Virus (HIV) care centre among people with HIV (PWH) within South Africa (SA) using national laboratory database. Design We lin…
View article: Gynaecologic and breast cancers in women living with HIV in South Africa: A record linkage study
Gynaecologic and breast cancers in women living with HIV in South Africa: A record linkage study Open
Breast and gynaecologic cancers account for approximately half of all cancers diagnosed amongst women in South Africa, many of whom also live with HIV. We aimed to determine the incidence of and risk factors for developing breast and gynae…
View article: High Cancer Burden among Antiretroviral Therapy Users in Malawi: A Record Linkage Study of Observational Human Immunodeficiency Virus Cohorts and Cancer Registry Data
High Cancer Burden among Antiretroviral Therapy Users in Malawi: A Record Linkage Study of Observational Human Immunodeficiency Virus Cohorts and Cancer Registry Data Open
Background: With antiretroviral therapy (ART), AIDS-defining cancer incidence has declined and non-AIDS-defining cancers (NADCs) are now more frequent among human immunodeficiency virus (HIV)-infected populations in high-income countries. …
View article: Cervical cancer prevention and care in HIV clinics across sub-Saharan Africa: results of a facility-based survey
Cervical cancer prevention and care in HIV clinics across sub-Saharan Africa: results of a facility-based survey Open
IntroductionAchieving cervical cancer (CC) elimination requires monitoring access to and quality of prevention and care services, particularly for women at high risk of disease, like women living with HIV (WLHIV).We assessed implementation…
View article: Decreasing incidence of conjunctival squamous cell carcinoma in people with HIV in South Africa
Decreasing incidence of conjunctival squamous cell carcinoma in people with HIV in South Africa Open
Background The main risk factors for squamous cell carcinoma of the conjunctiva (SCCC) are immunodeficiency and exposure to ultraviolet radiation. Little is known about SCCC epidemiology among people with HIV (PWH) in South Africa. Methods…
View article: Accuracy of screening tests for cervical pre-cancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia
Accuracy of screening tests for cervical pre-cancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia Open
Introduction To provide evidence to improve cervical screening for women living with HIV (WLHIV), we assessed the accuracy of screening tests that can be used in low-resource settings and give results at the same visit. Methods We conducte…
View article: Socioeconomic inequalities in cervical precancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia and Zimbabwe: analysis of Population-Based HIV Impact Assessment surveys
Socioeconomic inequalities in cervical precancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia and Zimbabwe: analysis of Population-Based HIV Impact Assessment surveys Open
Objectives We examined age, residence, education and wealth inequalities and their combinations on cervical precancer screening probabilities for women. We hypothesised that inequalities in screening favoured women who were older, lived in…
View article: Non-Specific Effects of Bacillus Calmette-Guérin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Non-Specific Effects of Bacillus Calmette-Guérin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Background: Vaccines induce antigen-specific immunity, which provides long-lived protection from the target pathogen. Trials from areas with high incidence rates for infectious diseases indicated that the tuberculosis vaccine Bacillus Calm…
View article: Age and Cancer Incidence in 5.2 Million People With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study
Age and Cancer Incidence in 5.2 Million People With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study Open
Background Old age is an important risk factor for developing cancer, but few data exist on this association in people with human immunodeficiency virus (HIV, PWH) in sub-Saharan Africa. Methods The South African HIV Cancer Match study is …
View article: Non-specific effects of Bacillus Calmette-Guérin - a systematic review and meta-analysis of randomized controlled trials
Non-specific effects of Bacillus Calmette-Guérin - a systematic review and meta-analysis of randomized controlled trials Open
Vaccines induce antigen-specific immunity which provides long-lived protection from the target pathogen. Trials especially from high infectious disease areas indicated that the tuberculosis vaccine Bacillus Calmette-Guérin (BCG) induces in…
View article: Access to Cervical Cancer Screening for Women Living With HIV: A Record Linkage Study.
Access to Cervical Cancer Screening for Women Living With HIV: A Record Linkage Study. Open
BackgroundAccording to the Global Strategy to Accelerate the Elimination of Cervical Cancer launched by the World Health Organizations (WHO), 70% of all women should undergo cervical cancer (CC) screening by 2030. While integrated HIV care…
View article: Cervical cancer prevention in countries with the highest HIV prevalence: a review of policies
Cervical cancer prevention in countries with the highest HIV prevalence: a review of policies Open
View article: Intravenous iron versus oral iron versus no iron with or without erythropoiesis- stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta-analysis
Intravenous iron versus oral iron versus no iron with or without erythropoiesis- stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta-analysis Open
When considering ESAs with iron as prevention for anaemia, one has to balance between efficacy and safety. Results suggest that treatment with ESA and iron probably decreases number of blood transfusions, but may increase mortality and the…
View article: Indicators and targets for cervical cancer prevention in countries with the highest HIV burden: A scoping review protocol
Indicators and targets for cervical cancer prevention in countries with the highest HIV burden: A scoping review protocol Open
IntroductionInequities and inequalities in cervical cancer (CC) incidence and mortality persist between high-and low-income countries.In several countries with high human Immunodeficiency virus (HIV) prevalence, prevention strategies and p…
View article: Cohort profile: the South African HIV Cancer Match (SAM) Study, a national population-based cohort
Cohort profile: the South African HIV Cancer Match (SAM) Study, a national population-based cohort Open
Purpose The South African HIV Cancer Match (SAM) Study is a national cohort of people living with HIV (PLWH). It was created using probabilistic record linkages of routine laboratory records of PLWH retrieved by National Health Laboratory …
View article: Socioeconomic inequalities in cervical pre-cancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia, and Zimbabwe – Analysis of Population-Based HIV Impact Assessment surveys
Socioeconomic inequalities in cervical pre-cancer screening among women in Ethiopia, Malawi, Rwanda, Tanzania, Zambia, and Zimbabwe – Analysis of Population-Based HIV Impact Assessment surveys Open
Background: Screening for cervical pre-cancerous lesions may be inequitable among women in sub-Saharan African countries. This study examined age, residence, education and wealth inequalities and their combinations on cervical pre-cancer s…
View article: Cervical Cancer Screening Cascade for women living with HIV: A cohort study from Zimbabwe
Cervical Cancer Screening Cascade for women living with HIV: A cohort study from Zimbabwe Open
Countries with high HIV prevalence, predominantly in sub-Sahahran Africa, have the highest cervical cancer rates globally. HIV care cascades successfully facilitated the scale-up of antiretroviral therapy. A cascade approach could similarl…
View article: Cervical cancer in women living in South Africa: a record linkage study of the National Health Laboratory Service and the National Cancer Registry
Cervical cancer in women living in South Africa: a record linkage study of the National Health Laboratory Service and the National Cancer Registry Open
HIV positive women presented a decade earlier with CC compared to HIV negative women. A large proportion of women with CC were unaware of their HIV status with a disproportionate burden of CC in Black women. We recommend women attending CC…
View article: Cancer incidence among people living with <scp>HIV</scp> in Zimbabwe: A record linkage study
Cancer incidence among people living with <span>HIV</span> in Zimbabwe: A record linkage study Open
Background People living with HIV (PLWH) are at increased risk of developing cancer. Cancer diagnoses are often incompletely captured at antiretroviral therapy (ART) clinics. Aim To estimate the incidence and explore risk factors of cancer…
View article: Cancer in HIV-positive and HIV-negative adolescents and young adults in South Africa: a cross-sectional study
Cancer in HIV-positive and HIV-negative adolescents and young adults in South Africa: a cross-sectional study Open
Objective To determine the spectrum of cancers in adolescents and young adults (AYAs) living with and without HIV in South Africa. Design Cross-sectional study with cancer records provided by the National Cancer Registry (NCR) and HIV reco…