Julia Butt
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View article: The association between human papillomavirus type 16 seropositivity and oropharyngeal cancer among men living with HIV
The association between human papillomavirus type 16 seropositivity and oropharyngeal cancer among men living with HIV Open
Background There are no methods for the early detection of human papillomavirus–driven oropharyngeal squamous cell carcinoma (HPV+OPSCC); however, HPV16 E6 seropositivity has been identified as a promising screening marker. Although people…
View article: Multiplex serology for Streptobacillus moniliformis and other ‘rat bite fever-like’ microorganisms for seroprevalence studies in rodents
Multiplex serology for Streptobacillus moniliformis and other ‘rat bite fever-like’ microorganisms for seroprevalence studies in rodents Open
Rat bite fever (RBF) is a zoonotic disease caused primarily by Streptobacillus ( S .) moniliformis . Norway or brown rats ( Rattus [ R. ] norvegicus ) are the natural host for S. moniliformis and carry the bacterium in the nasopharynx with…
View article: Adverse childhood experiences and adult stress eating
Adverse childhood experiences and adult stress eating Open
Adverse childhood experiences (ACEs) are an indicator of childhood trauma and are associated with worse adult health outcomes. We examined the association of ACEs and adult stress eating in a largely low-income and racially diverse populat…
View article: A Retrospective Study of IV Transmitted Diseases through Blood Products among Blood Donors at AIMTH
A Retrospective Study of IV Transmitted Diseases through Blood Products among Blood Donors at AIMTH Open
Objectives: To assess the Frequency of IV transmitted Diseases through blood products among blood donors at AIMTH, Sialkot. Methodology: An observational retrospective study was conducted in August 2023.The data was collected from June 202…
View article: SARS-CoV-2 antibody and neutralization dynamics among persons with natural- and vaccine-induced exposures
SARS-CoV-2 antibody and neutralization dynamics among persons with natural- and vaccine-induced exposures Open
Previous SARS-CoV-2 research indicates that antibody levels and corresponding neutralization potential increase with additional exposures (comprising vaccination or infection), and that hybrid immunity resulting from combined vaccination a…
View article: Calibrating multiplex serology for Helicobacter pylori
Calibrating multiplex serology for Helicobacter pylori Open
View article: Epstein–Barr Virus Serology Associated With Persistent Oral Human Papillomavirus Infections in Men
Epstein–Barr Virus Serology Associated With Persistent Oral Human Papillomavirus Infections in Men Open
Background Most people acquire Epstein–Barr virus (EBV) and certain human papillomaviruses (HPVs) during their lifetime. HPV‐related oropharyngeal carcinomas have increased in recent decades, particularly among men. The role of coinfection…
View article: Epstein-Barr virus (EBV) serology and its impact on oral human papillomavirus (HPV) infection outcomes in children during early childhood
Epstein-Barr virus (EBV) serology and its impact on oral human papillomavirus (HPV) infection outcomes in children during early childhood Open
Epstein-Barr virus (EBV) and various human papillomaviruses (HPVs) commonly infect the oral mucosa, yet the longitudinal effects of these infections and their potential coinfections remain poorly understood. This study investigated whether…
View article: Murine astrovirus infection course and antibody response in different mouse strains
Murine astrovirus infection course and antibody response in different mouse strains Open
Monitoring the health of mice used in animal experiments constitutes an important instrument toward microbiological standardization, as infections can alter physiological parameters and immune reactions and may therefore have an essential …
View article: Maternal–fetal transfer and longitudinal trends of antibodies to <i>Chlamydia trachomatis</i> and <i>Mycoplasma genitalium</i> in early childhood
Maternal–fetal transfer and longitudinal trends of antibodies to <i>Chlamydia trachomatis</i> and <i>Mycoplasma genitalium</i> in early childhood Open
Introduction Sexually transmitted infections caused by Chlamydia trachomatis and Mycoplasma genitalium can have significant implications during early childhood. This study aimed to assess maternal antibodies to C. trachomatis and M. genita…
View article: Supplementary Table S1 from Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies
Supplementary Table S1 from Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies Open
Supplementary Table S1: Heatmap of HPV16 antibody profiles. HPV16-specific antibody profiles are presented for the subset of participants with seroreactivity against at least one HPV16 E protein.
View article: Data from Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies
Data from Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies Open
Individuals living with human immunodeficiency virus (HIV) are at a higher risk for developing human papillomavirus–driven oropharyngeal squamous cell carcinoma (HPV + OPSCC). There are no methods for early detection; however, HPV16 E6 ant…
View article: Helicobacter pylori multiplex serology and its dynamics within families during a 3-year prospective follow-up
Helicobacter pylori multiplex serology and its dynamics within families during a 3-year prospective follow-up Open
Our results perfectly agree with a recently published register-linkage study from Finland, where Hp and Hp-related co-morbidity are predicted to disappear among the native Finns during the 21st century.
View article: Time course and determinants of the antibody response to SARS-CoV-2 in Costa Rica: the RESPIRA study
Time course and determinants of the antibody response to SARS-CoV-2 in Costa Rica: the RESPIRA study Open
RESPIRA Study ClinicalTrials.gov ID: NCT04537338 (3 September 2020).
View article: Basal T cell activation predicts yellow fever vaccine response independently of cytomegalovirus infection and sex-related immune variations
Basal T cell activation predicts yellow fever vaccine response independently of cytomegalovirus infection and sex-related immune variations Open
View article: Risk factors associated with IgG seropersistence to <i>Chlamydia trachomatis</i> and <i>Mycoplasma genitalium</i>
Risk factors associated with IgG seropersistence to <i>Chlamydia trachomatis</i> and <i>Mycoplasma genitalium</i> Open
Sexually transmitted infections caused by Chlamydia trachomatis (Ct) and Mycoplasma genitalium (Mg) have significant implications both at the individual and societal levels. Our study evaluated various co-factors associated with persistent…
View article: Associations of several common infections with amyloid‐β pathology <i>in vivo</i>: a population‐based study
Associations of several common infections with amyloid‐β pathology <i>in vivo</i>: a population‐based study Open
Background Associations of common infections with Alzheimer’s disease have been reported, but potential mechanisms underlying these relationships are unclear. A hypothesised mechanism is amyloid‐beta (Aβ) aggregation as a defense mechanism…
View article: Association of Antibody Responses to Helicobacter pylori Proteins with Colorectal Adenoma and Colorectal Cancer
Association of Antibody Responses to Helicobacter pylori Proteins with Colorectal Adenoma and Colorectal Cancer Open
Helicobacter pylori (H. pylori) has been implicated in colorectal carcinogenesis. Here, the association of immune responses to bacterial exposure with advancing stages of colorectal neoplasia was assessed by multiplex serology. Immunoglobu…
View article: Herpesvirus Antibody Response and Occurrence of Symptoms in Acute and Post-Acute COVID-19 Disease
Herpesvirus Antibody Response and Occurrence of Symptoms in Acute and Post-Acute COVID-19 Disease Open
Knowledge about the underlying causes of the individual occurrence of symptoms during acute COVID-19 disease and during the post-acute sequelae of COVID-19 is limited. In a German COVID-19 follow-up study, we assessed whether elevated anti…
View article: Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents
Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents Open
Background Helicobacter pylori colonizes the human stomach and may affect the inflammatory response, hormone production related to energy regulation, and gastrointestinal microbiota composition. Previous studies have explored a potential a…
View article: Prospective evaluation of the relevance of Epstein–Barr virus antibodies for early detection of nasopharyngeal carcinoma in Chinese adults
Prospective evaluation of the relevance of Epstein–Barr virus antibodies for early detection of nasopharyngeal carcinoma in Chinese adults Open
Background Epstein–Barr virus (EBV) is a major cause of nasopharyngeal carcinoma (NPC) and measurement of different EBV antibodies in blood may improve early detection of NPC. Prospective studies can help assess the roles of different EBV …
View article: COVID-19 and long-term impact on symptoms and Health-Related Quality of Life in Costa Rica: the RESPIRA cohort study
COVID-19 and long-term impact on symptoms and Health-Related Quality of Life in Costa Rica: the RESPIRA cohort study Open
Background Evidence continues to accumulate regarding the potential long-term health consequences of COVID-19 in the population. To distinguish between COVID-19-related symptoms and health limitations from those caused by other conditions,…
View article: Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis Open
Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise mechanisms for such influences are still unclear. A large-scal…
View article: Advancing <i>Toxoplasma gondii</i> multiplex serology
Advancing <i>Toxoplasma gondii</i> multiplex serology Open
Toxoplasma gondii is a highly prevalent pathogen causing zoonotic infections with significant public health implications. Yet, our understanding of long-term consequences, associated risk factors, and the potential role of co-infections is…
View article: No clear evidence for relationships of Apolipoprotein E genotype with measures of common infections in three UK cohorts
No clear evidence for relationships of Apolipoprotein E genotype with measures of common infections in three UK cohorts Open
APOE genotype is the strongest genetic risk factor for late onset Alzheimer’s disease, with the ε2 and ε4 alleles decreasing and increasing risk relative to the ε3 allele, respectively. Although evidence has been conflicting, several commo…
View article: <i>Helicobacter pylori</i>seropositivity associates with hyperglycemia, but not obesity in Danish children and adolescents
<i>Helicobacter pylori</i>seropositivity associates with hyperglycemia, but not obesity in Danish children and adolescents Open
Helicobacter pylori colonizes the human stomach and may affect the inflammatory response, hormone production related to energy regulation, and gut microbiota composition. Previous studies have demonstrated an inverse correlation between H.…
View article: Common infections and neuroimaging markers of dementia in three UK cohort studies
Common infections and neuroimaging markers of dementia in three UK cohort studies Open
INTRODUCTION We aimed to investigate associations between common infections and neuroimaging markers of dementia risk (brain volume, hippocampal volume, white matter lesions) across three population‐based studies. METHODS We tested associa…
View article: <i>Helicobacter hepaticus</i> and <i>Helicobacter bilis</i> in liver and biliary cancers from ATBC and PLCO
<i>Helicobacter hepaticus</i> and <i>Helicobacter bilis</i> in liver and biliary cancers from ATBC and PLCO Open
Background Helicobacter species (spp.) have been detected in human bile and hepatobiliary tissue Helicobacter spp. promote gallstone formation and hepatobiliary tumors in laboratory studies, though it remains unclear whether Helicobacter s…
View article: Infectious pathogens and risk of esophageal, gastric and duodenal cancers and ulcers in China: A case‐cohort study
Infectious pathogens and risk of esophageal, gastric and duodenal cancers and ulcers in China: A case‐cohort study Open
Infection by certain pathogens is associated with cancer development. We conducted a case‐cohort study of ~2500 incident cases of esophageal, gastric and duodenal cancer, and gastric and duodenal ulcer and a randomly selected subcohort of …
View article: Impact of age at vaccination and cervical HPV infection status on binding and neutralizing antibody titers at 10 years after receiving single or higher doses of quadrivalent HPV vaccine
Impact of age at vaccination and cervical HPV infection status on binding and neutralizing antibody titers at 10 years after receiving single or higher doses of quadrivalent HPV vaccine Open
Long-term follow-up of a cohort of unmarried girls who received one, two, or three doses of quadrivalent HPV vaccine, between 10 and 18 years of age, in an Indian multi-centric study allowed us to compare antibody responses between the you…