Julia Debik
YOU?
Author Swipe
View article: Sources of variation in the serum metabolome of female participants of the HUNT2 study
Sources of variation in the serum metabolome of female participants of the HUNT2 study Open
The aim of this study was to explore the intricate relationship between serum metabolomics and lifestyle factors, shedding light on their impact on health in the context of breast cancer risk. Detailed metabolic profiles of 2283 female par…
View article: Profiling of serum metabolome of breast cancer: multi-cancer features discriminate between healthy women and patients with breast cancer
Profiling of serum metabolome of breast cancer: multi-cancer features discriminate between healthy women and patients with breast cancer Open
Introduction The progression of solid cancers is manifested at the systemic level as molecular changes in the metabolome of body fluids, an emerging source of cancer biomarkers. Methods We analyzed quantitatively the serum metabolite profi…
View article: Association of serum metabolome profile with the risk of breast cancer in participants of the HUNT2 study
Association of serum metabolome profile with the risk of breast cancer in participants of the HUNT2 study Open
Background The serum metabolome is a potential source of molecular biomarkers associated with the risk of breast cancer. Here we aimed to analyze metabolites present in pre-diagnostic serum samples collected from healthy women participatin…
View article: Effect of Delayed Centrifugation on the Levels of NMR-Measured Lipoproteins and Metabolites in Plasma and Serum Samples
Effect of Delayed Centrifugation on the Levels of NMR-Measured Lipoproteins and Metabolites in Plasma and Serum Samples Open
Metabolic profiling is widely used for large-scale association studies, based on biobank material. The main obstacle to the translation of metabolomic findings into clinical application is the lack of standardization, making validation in …
View article: Lipoprotein and metabolite associations to breast cancer risk in the HUNT2 study
Lipoprotein and metabolite associations to breast cancer risk in the HUNT2 study Open
Background The aim of this study was to investigate if serum lipoprotein and metabolic profiles of healthy women can predict the risk of developing breast cancer in the future, and to gain a better understanding of the etiology of the dise…
View article: Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients
Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients Open
Patients with locally advanced breast cancer have a worse prognosis compared to patients with localized tumors and require neoadjuvant treatment before surgery. The aim of this study was to characterize the systemic metabolic effect of neo…
View article: Serum levels of inflammation‐related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Serum levels of inflammation‐related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers Open
Angiogenesis is necessary for tumor growth and has been targeted in breast cancer; however, it is unclear which patients will respond and benefit from antiangiogenic therapy. We report noninvasive monitoring of patient response to neoadjuv…
View article: Using Ensemble Methods to Improve the Performance of Prediction - Statistical Analysis of a Myocardial Infarction Data Set from the HUNT Study
Using Ensemble Methods to Improve the Performance of Prediction - Statistical Analysis of a Myocardial Infarction Data Set from the HUNT Study Open
The main focus of this thesis is to evaluate the use of ensemble methods to improve the\nperformance of prediction, when applied on a myocardial infarction (MI) data set from the\nHUNT study. The data set comes from a prospective case-cont…