Julia Elrod
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View article: Provider Survey on Burn Care in India
Provider Survey on Burn Care in India Open
Background: Burns result in approximately 180,000 deaths annually, with the majority occurring in rural regions of Africa and Southeast Asia. This study aimed to assess the available resources, key challenges, and potential solutions in bu…
View article: A call for lifelong follow-up in CDH: Identifying recurrence patterns and the importance of routine monitoring
A call for lifelong follow-up in CDH: Identifying recurrence patterns and the importance of routine monitoring Open
CDH recurrences occur across all ages and often remain asymptomatic. Structured lifelong follow-up facilitates early detection and intervention, preventing severe complications. These findings support routine surveillance and the establish…
View article: Growth challenges and recovery in 1247 children with congenital diaphragmatic hernia: a 10-year follow-up
Growth challenges and recovery in 1247 children with congenital diaphragmatic hernia: a 10-year follow-up Open
Growth abnormalities in children with congenital diaphragmatic hernia (CDH) are a significant concern for long-term developmental outcomes. To explore growth in this population, the evolution of weight, height, body mass index (BMI), and h…
View article: Thoracoscopic hiatoplasty in congenital diaphragmatic hernia is safe and less invasive: a prospective propensity-matched short-term study
Thoracoscopic hiatoplasty in congenital diaphragmatic hernia is safe and less invasive: a prospective propensity-matched short-term study Open
Background Congenital diaphragmatic hernia (CDH) is a condition linked to neonatal morbidity, mortality, and gastroesophageal reflux. Traditional hiatoplasty via laparotomy or laparoscopy is complicated by abdominal adhesions from previous…
View article: Hospital Volume and Outcome in the Treatment of Congenital Diaphragmatic Hernia in Germany – Observational Study Using National Hospital Discharge Data From 2016 to 2023
Hospital Volume and Outcome in the Treatment of Congenital Diaphragmatic Hernia in Germany – Observational Study Using National Hospital Discharge Data From 2016 to 2023 Open
These findings indicate that high-volume centers treat a greater proportion of severe cases and that they may achieve better outcomes for the most critically ill patients, as reflected by lower ECMO-specific mortality.
View article: Availability, effectiveness and safety of cadaveric and fresh allogeneic skin grafts in pediatric burn care—a review
Availability, effectiveness and safety of cadaveric and fresh allogeneic skin grafts in pediatric burn care—a review Open
Burn injuries in children are a critical public health issue with significant mortality and morbidity. Allogeneic skin grafts, both cadaveric and freshly donated, have been utilized in pediatric burn care since many years, yet their effica…
View article: Country economic status is strongly associated with burn survival - validation of the (modified) ABSI
Country economic status is strongly associated with burn survival - validation of the (modified) ABSI Open
Background Predicting burn-related mortality is vital for family counseling, triage, and resource allocation. Several of the burn-specific mortality prediction scores have been developed, including the Abbreviated Burn Severity Index (ABSI…
View article: Assessment of Brain Development in Children With Congenital Diaphragmatic Hernia – an Automated Brain Segmentation Approach
Assessment of Brain Development in Children With Congenital Diaphragmatic Hernia – an Automated Brain Segmentation Approach Open
The study reveals neurodevelopmental differences in children with CDH, particularly in those requiring ECMO therapy. Increased CT, GM, and CSF volumes suggest complex neurodevelopmental challenges.
View article: Long-Term Outcomes of a Cultured Autologous Dermo-Epidermal Skin Substitute in Children: 5-Year Results of a Phase I Clinical Trial
Long-Term Outcomes of a Cultured Autologous Dermo-Epidermal Skin Substitute in Children: 5-Year Results of a Phase I Clinical Trial Open
Limited donor sites and poor long-term outcomes with standard treatment for large skin defects remain a huge problem. An autologous, bilayered, laboratory-grown skin substitute (denovoSkin) was developed to overcome this problem and has sh…
View article: Neutrophil Extracellular Traps: A Crucial Factor in Post-Surgical Abdominal Adhesion Formation
Neutrophil Extracellular Traps: A Crucial Factor in Post-Surgical Abdominal Adhesion Formation Open
Post-surgical abdominal adhesions, although poorly understood, are highly prevalent. The molecular processes underlying their formation remain elusive. This review aims to assess the relationship between neutrophil extracellular traps (NET…
View article: The Dual Role of Neutrophil Extracellular Traps (NETs) in Sepsis and Ischemia-Reperfusion Injury: Comparative Analysis across Murine Models
The Dual Role of Neutrophil Extracellular Traps (NETs) in Sepsis and Ischemia-Reperfusion Injury: Comparative Analysis across Murine Models Open
A better understanding of the function of neutrophil extracellular traps (NETs) may facilitate the development of interventions for sepsis. The study aims to investigate the formation and degradation of NETs in three murine sepsis models a…
View article: Barriers and prospects for skin grafting in burn treatment across African countries
Barriers and prospects for skin grafting in burn treatment across African countries Open
Skin grafting is not performed in a significant number of hospitals treating burns. The majority of the staff believe that more skin grafting would lead to a better outcome. Advocacy and improved infrastructure, human resources coupled wit…
View article: Encephalocele as a rare complication of conservatively managed cranial aplasia cutis in a boy with Adams–Oliver syndrome
Encephalocele as a rare complication of conservatively managed cranial aplasia cutis in a boy with Adams–Oliver syndrome Open
A 7-week-old boy who was born preterm (33 + 6 gestational age) with a large aplasia cutis congenita (ACC) of the skull (Fig. 1A), initially treated conservatively, developed an exophytic protrusion of 2.5 cm above the skin (Fig. 1B) and wa…
View article: DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis
DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis Open
Introduction Neutrophil extracellular traps (NETs) have various beneficial and detrimental effects in the body. It has been reported that some bacteria may evade the immune system when entangled in NETs. Thus, the aim of the current study …
View article: Fetal MRI-Based Mediastinal Shift Angle (MSA) and Percentage Area of Left Ventricle (pALV) as Prognostic Parameters for Congenital Diaphragmatic Hernia
Fetal MRI-Based Mediastinal Shift Angle (MSA) and Percentage Area of Left Ventricle (pALV) as Prognostic Parameters for Congenital Diaphragmatic Hernia Open
Objective: Fetal magnetic resonance imaging (MRI) is broadly used as a method for assessing prognosis in congenital diaphragmatic hernia (CDH). In addition to the extent of lung hypoplasia, determined by measuring the lung volume, cardiac …
View article: Radiomics-Assisted Computed Tomography-Based Analysis to Evaluate Lung Morphology Characteristics after Congenital Diaphragmatic Hernia
Radiomics-Assisted Computed Tomography-Based Analysis to Evaluate Lung Morphology Characteristics after Congenital Diaphragmatic Hernia Open
Purpose: Children with congenital diaphragmatic hernia suffer from long-term morbidity, including lung function impairment. Our study aims to analyze lung morphology characteristics via radiomic-assisted extraction of lung features in pati…
View article: As time goes by – Overlooking 40 years of inpatient burn treatment at a national pediatric burn center in Switzerland
As time goes by – Overlooking 40 years of inpatient burn treatment at a national pediatric burn center in Switzerland Open
The present data show pediatric burns to remain a major health burden in Switzerland, especially small and medium burns in preschool children. Prevention programs should focus on this age population as well as on scald and flame burns as m…
View article: Smoothing Lexis diagrams using kernel functions: A contemporary approach
Smoothing Lexis diagrams using kernel functions: A contemporary approach Open
Lexis diagrams are rectangular arrays of event rates indexed by age and period. Analysis of Lexis diagrams is a cornerstone of cancer surveillance research. Typically, population-based descriptive studies analyze multiple Lexis diagrams de…
View article: Clinical outcome, quality of life, and mental health in long-gap esophageal atresia: comparison of gastric sleeve pull-up and delayed primary anastomosis
Clinical outcome, quality of life, and mental health in long-gap esophageal atresia: comparison of gastric sleeve pull-up and delayed primary anastomosis Open
Introduction Pediatric surgeons have yet to reach a consensus whether a gastric sleeve pull-up or delayed primary anastomosis for the treatment of esophageal atresia (EA), especially of the long-gap type (LGEA) should be performed. Thus, t…
View article: Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns Open
Introduction Severe burns cause unique pathophysiological alterations especially on the immune system. A murine scald model was optimized as a basis for the understanding of immunological reactions in response to heat induced injury. The u…
View article: Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox
Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox Open
Background: Severe infections that culminate in sepsis are associated with high morbidity and mortality. Despite continuous efforts in basis science and clinical research, evidence based-therapy is mostly limited to basic causal and suppor…
View article: Midgut volvulus adds a neutrophil-driven model of murine sepsis to the experimental hyperinflammation toolbox
Midgut volvulus adds a neutrophil-driven model of murine sepsis to the experimental hyperinflammation toolbox Open
Background: Severe infections that culminate in sepsis are associated with high morbidity and mortality. Despite continuous efforts in basis science and clinical research, evidence based-therapy is mostly limited to basic causal and suppor…
View article: cfDNA and DNases: New Biomarkers of Sepsis in Preterm Neonates—A Pilot Study
cfDNA and DNases: New Biomarkers of Sepsis in Preterm Neonates—A Pilot Study Open
Introduction: An early and accurate diagnosis of early onset neonatal sepsis (EONS) and late onset neonatal sepsis (LONS) is essential to improve the outcome of this devastating conditions. Especially, preterm infants are at risk. Reliable…
View article: Fetal-Maternal Surgery for Spina Bifida in a HIV-Infected Mother
Fetal-Maternal Surgery for Spina Bifida in a HIV-Infected Mother Open
Introduction: In select cases, in utero surgery for myelomeningocele (MMC) leads to better outcomes than postnatal repair. However, maternal HIV infection constitutes a formal exclusion criterion due to the potential of vertical HIV transm…