Julia List
YOU?
Author Swipe
View article: Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses Open
Despite major therapeutic advances in the treatment of acute lymphoblastic leukemia (ALL), resistances and long-term toxicities still pose significant challenges. Cyclins and their associated cyclin-dependent kinases are one focus of cance…
View article: Boosting the anti-tumor activity of natural killer cells by caripe 8 – A Carapichea ipecacuanha isolated cyclotide
Boosting the anti-tumor activity of natural killer cells by caripe 8 – A Carapichea ipecacuanha isolated cyclotide Open
Cyclotides are head-to-tail cyclized peptides with a unique cystine-knot motif. Their structure provides exceptional resistance against enzymatic, chemical, or thermal degradation compared to other peptides. Peptide-based therapeutics prom…
View article: A lineage-specific <i>STAT5B</i> N642H mouse model to study NK-cell leukemia
A lineage-specific <i>STAT5B</i> N642H mouse model to study NK-cell leukemia Open
Patients with T- and natural killer (NK)-cell neoplasms frequently have somatic STAT5B gain-of-function mutations. The most frequent STAT5B mutation is STAT5BN642H, which is known to drive murine T-cell leukemia, although its role in NK-ce…
View article: A lineage-specific<i>STAT5B</i><sup>N642H</sup>mouse model to study NK-cell leukemia
A lineage-specific<i>STAT5B</i><sup>N642H</sup>mouse model to study NK-cell leukemia Open
Patients with T- and NK-cell neoplasms frequently have somatic STAT5B gain-of-function mutations. The most frequent STAT5B mutation is STAT5B N642H , which is known to drive murine T-cell leukemia although its role in NK-cell malignancies …
View article: Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer
Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer Open
Background Tumor-associated macrophages (TAM) constitute the most abundant immune cells in the tumor stroma initiating pro-inflammatory (M1) or immunosuppressive (M2) responses depending on their polarization status. Advances in tumor immu…
View article: Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2
Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2 Open
NK cells are innate lymphocytes responsible for lysis of pathogen‐infected and transformed cells. One of the major activating receptors required for target cell recognition is the NK group 2D (NKG2D) receptor. Numerous reports show the nec…