Julia Pickert
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View article: Immediate-Type Hypersensitivity to Polyethylene Glycol (PEG) and a PEG-Containing COVID-19 Vaccine Revealed by Intradermal Testing
Immediate-Type Hypersensitivity to Polyethylene Glycol (PEG) and a PEG-Containing COVID-19 Vaccine Revealed by Intradermal Testing Open
Determination of serum parametersConcentrations of mast cell tryptase (2.3µg/mL), total IgE (109kU/L) and allergen-specific IgE topenicilloyl G and V, ampicilloyl, amoxicilloyl, ethylene oxide, the major birch pollen allergen Bet v 1 (4.61…
View article: Long-term impact of hymenoptera venom immunotherapy on clinical course, immune parameters, and psychosocial aspects
Long-term impact of hymenoptera venom immunotherapy on clinical course, immune parameters, and psychosocial aspects Open
VIT leads to long-term tolerance in the majority of HV-allergic patients, however, ~ 1/5 may lose protection over time, arguing for continued follow-up on VIT-treated subjects and keeping them equipped with an emergency kit. Notably, VIT a…
View article: Biologics for atopic diseases: Indication, side effect management, and new developments
Biologics for atopic diseases: Indication, side effect management, and new developments Open
With the advent of biologicals, more and more therapeutics are available that specifically address specific switch points in the pathomechanism of immunologically dominated diseases. Thus, the focus of diagnostics and therapy (precision me…
View article: The global impact of the COVID‐19 pandemic on the management and course of chronic urticaria
The global impact of the COVID‐19 pandemic on the management and course of chronic urticaria Open
Introduction The COVID‐19 pandemic dramatically disrupts health care around the globe. The impact of the pandemic on chronic urticaria (CU) and its management are largely unknown. Aim To understand how CU patients are affected by the COVID…
View article: Healthcare provision for insect venom allergy patients during the COVID-19 pandemic
Healthcare provision for insect venom allergy patients during the COVID-19 pandemic Open
The population prevalence of insect venom allergy ranges between 3–5%, and it can lead to potentially life-threatening allergic reactions. Patients who have experienced a systemic allergic reaction following an insect sting should be refer…
View article: Omalizumab response correlates with reduced <scp>IFN</scp> ‐γ‐, <scp>IL</scp> ‐10‐ and <scp>IL</scp> ‐31‐secreting cells in chronic spontaneous urticaria
Omalizumab response correlates with reduced <span>IFN</span> ‐γ‐, <span>IL</span> ‐10‐ and <span>IL</span> ‐31‐secreting cells in chronic spontaneous urticaria Open
Background The anti‐IgE antibody omalizumab has been approved for the treatment of chronic spontaneous urticaria ( CSU ) in patients insufficiently responding to antihistamines. However, its mode of action in CSU is not clearly understood.…
View article: Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus
Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus Open
Lichen planus (LP) is a common, chronic relapsing inflammatory disorder of the skin and mucous membranes which often poses a major therapeutic challenge due to its refractory course. Novel pathogenesis-based therapies are urgently needed. …
View article: Thymoma-Associated Paraneoplastic Autoimmune Multiorgan Syndrome—From Pemphigus to Lichenoid Dermatitis
Thymoma-Associated Paraneoplastic Autoimmune Multiorgan Syndrome—From Pemphigus to Lichenoid Dermatitis Open
Introduction: Paraneoplastic autoimmune multi-organ syndrome (PAMS) is a rare clinical condition characterized by variable and heterogeneous clinical phenotypes in the presence of neoplasias which largely depend on the activation of humora…