Julia Pollmann
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View article: Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients
Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients Open
A large proportion of HIV-coinfected visceral leishmaniasis (VL-HIV) patients exhibit chronic disease with frequent VL recurrence. However, knowledge on immunological determinants underlying the disease course is scarce. We longitudinally …
View article: Persistent T cell unresponsiveness associated with chronic VL disease in VL-HIV patients
Persistent T cell unresponsiveness associated with chronic VL disease in VL-HIV patients Open
Data for "Persistent T cell unresponsiveness associated with chronic VL disease in VL-HIV patients" Data directory Contains processed single-cell RNA and TCR sequencing of two individuals per group. Patient and grouping information is prov…
View article: Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients
Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients Open
A large proportion of HIV-coinfected visceral leishmaniasis (VL) patients exhibit a chronic disease course with frequent recurrence of VL, despite successful viral suppression and initial parasitological cure. Due to a hard-to-reach popula…
View article: Evaluation of C-reactive protein and myxovirus resistance protein A to guide the rational use of antibiotics among acute febrile adult patients in Northwest Ethiopia
Evaluation of C-reactive protein and myxovirus resistance protein A to guide the rational use of antibiotics among acute febrile adult patients in Northwest Ethiopia Open
An over-prescription of antibiotics for febrile patients was observed, even for those with low CRP levels and without a confirmed bacterial infection. The added value of the FebriDx was limited, while the combined use of rapid tests for qC…
View article: The impact of digital contact tracing on the SARS-CoV-2 pandemic - a comprehensive modelling study
The impact of digital contact tracing on the SARS-CoV-2 pandemic - a comprehensive modelling study Open
Contact tracing is one of several strategies employed in many countries to curb the spread of SARS-CoV-2. Digital contact tracing (DCT) uses tools such as cell-phone applications to improve tracing speed and reach. We model the impact of D…
View article: Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis Open
Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymera…
View article: Digital Contact Tracing Service: An improved decentralized design for privacy and effectiveness
Digital Contact Tracing Service: An improved decentralized design for privacy and effectiveness Open
We propose a decentralized digital contact tracing service that preserves the users' privacy by design while complying to the highest security standards. Our approach is based on Bluetooth and measures actual encounters of people, the cont…
View article: Hepatitis C Virus and Human Cytomegalovirus—Natural Killer Cell Subsets in Persistent Viral Infections
Hepatitis C Virus and Human Cytomegalovirus—Natural Killer Cell Subsets in Persistent Viral Infections Open
Hepatitis C virus (HCV) and human cytomegalovirus (HCMV) are prominent examples of RNA and DNA viruses, respectively, that establish a persistent infection in their host. HCV affects over 185 million patients worldwide, who are at high ris…
View article: Of Natural Killer cells and Hepatitis C Virus
Of Natural Killer cells and Hepatitis C Virus Open
Natural Killer (NK) cells are important effector cells in Hepatitis C Virus (HCV) infection, a virus that chronically infects around 2.5% of the world population and is a major cause of liver disease and hepatocellular carcinoma. The exact…
View article: The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells Open
Natural Killer (NK) cells are innate effector cells that are able to recognize and eliminate tumor cells through engagement of their surface receptors. NKp30 is a potent activating NK cell receptor that elicits efficient NK cell-mediated t…